Annotation Detail for LCK
Basic Information Top
| Gene Symbol: | LCK ( LSK,YT16,p56lck,pp58lck ) |
|---|---|
| Gene Full Name: | lymphocyte-specific protein tyrosine kinase |
| Band: | 1p35.2 |
| Quick Links | Entrez ID:3932; OMIM: 153390; Uniprot ID:LCK_HUMAN; ENSEMBL ID: ENSG00000182866; HGNC ID: 6524 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 102 | Phosphoserine. | |
| 159 | Phosphothreonine. | |
| 162 | Phosphoserine. | |
| 179 | N6-acetyllysine. | |
| 192 | Phosphotyrosine. | |
| 194 | Phosphoserine. | |
| 213 | Phosphoserine. | |
| 394 | Phosphotyrosine; by autocatalysis. | |
| 501 | Phosphothreonine. | |
| 505 | Phosphotyrosine. | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 2 | N-myristoyl glycine (By similarity). | Swiss-Prot 53.0 |
| 3 | S-palmitoyl cysteine (By similarity). | Swiss-Prot 53.0 |
| 5 | S-palmitoyl cysteine (By similarity). | Swiss-Prot 53.0 |
| 41 | Phosphoserine (MAPK1;MAPK3) | Phospho.ELM 6.0 |
| 157 | Phosphoserine | Phospho.ELM 6.0 |
| 162 | Phosphoserine. | Swiss-Prot 53.0 |
| 191 | Phosphotyrosine | Phospho.ELM 6.0 |
| 192 | Phosphotyrosine. | Swiss-Prot 53.0 |
| 193 | Phosphoserine | Phospho.ELM 6.0 |
| 213 | Phosphoserine. | Swiss-Prot 53.0 |
| 393 | Phosphotyrosine (Lck) | Phospho.ELM 6.0 |
| 394 | Phosphotyrosine (by autocatalysis). | Swiss-Prot 53.0 |
| 501 | Phosphothreonine. | Swiss-Prot 53.0 |
| 504 | Phosphotyrosine (Lck) | Phospho.ELM 6.0 |
| 505 | Phosphotyrosine. | Swiss-Prot 53.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 40 | N-linked | HMM predict |
| 59 | Phosphoserine(MAPK) | HMM predict |
| 130 | Methyllysine | HMM predict |
| 135 | Methyllysine | HMM predict |
| 158 | Phosphoserine(IKK) | HMM predict |
| 162 | Phosphoserine(IKK) | HMM predict |
| 192 | Phosphotyrosine(INSR) | HMM predict |
| 194 | Phosphoserine(CDC2) | HMM predict |
| 211 | N-linked | HMM predict |
| 313 | Phosphotyrosine(EGFR) | HMM predict |
| 313 | Phosphotyrosine(Jak) | HMM predict |
| 321 | N-linked | HMM predict |
| 394 | Phosphotyrosine(Syk) | HMM predict |
| 394 | Phosphotyrosine(Jak) | HMM predict |
| 394 | Phosphotyrosine(INSR) | HMM predict |
| 394 | Phosphotyrosine | HMM predict |
| 470 | Phosphotyrosine(SRC) | HMM predict |
| 489 | Phosphotyrosine(Jak) | HMM predict |
| 505 | Phosphotyrosine(SRC) | HMM predict |
| 505 | Phosphotyrosine | HMM predict |
- RefSeq ID: NM_005356
- Location:chr1 32489426-32524351
- strand:+
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| H3ac | HepG2 | E | 32488602 | 32489191 | 589 | 530 |
| hScc1 | CdLS | GSE12603 | 32488083 | 32488744 | 661 | 1013 |
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| H3ac | HepG2 | E | 32490749 | 32491091 | 342 | 0 |
| p130 | shRbQuiescent | GSE19898 | 32505001 | 32505529 | 528 | 0 |
| Micro RNA Name | Stem Loop Name | The chromosome that miRNA located | Publication |
|---|---|---|---|
| hsa-miR-337-5p | hsa-mir-337 | 14 | 19290526 |
| No data |
Cis-Nats regulation