AutismKB 2.0

Annotation Detail for LCP1


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Basic Information Top
Gene Symbol:LCP1 ( CP64,DKFZp781A23186,FLJ25423,FLJ26114,FLJ39956,L-PLASTIN,LC64P,LPL,PLS2 )
Gene Full Name: lymphocyte cytosolic protein 1 (L-plastin)
Band: 13q14.13
Quick LinksEntrez ID:3936; OMIM: 153430; Uniprot ID:PLSL_HUMAN; ENSEMBL ID: ENSG00000136167; HGNC ID: 6528
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
5Phosphoserine.
7Phosphoserine.
28Phosphotyrosine.
30Phosphoserine.
76N6-acetyllysine.
88N6-acetyllysine.
124Phosphotyrosine.
276Phosphotyrosine.
294N6-acetyllysine.
297N6-acetyllysine.
361N6-acetyllysine.
472N6-acetyllysine.
542N6-acetyllysine.
579N6-acetyllysine.
Location(AA) Modifications Resource
2N-acetylalanine.Swiss-Prot 53.0
4Phosphoserine (PKA
5Phosphoserine (By similarity).Swiss-Prot 53.0
6Phosphoserine (PKA
7Phosphoserine (By similarity).Swiss-Prot 53.0
124Phosphotyrosine.Swiss-Prot 53.0
Location(AA) Modification Resource
7PhosphoserineHMM predict
28Phosphotyrosine(INSR)HMM predict
28Phosphotyrosine(EGFR)HMM predict
111O-linkedHMM predict
111Phosphoserine(CK1)HMM predict
119Phosphoserine(CK2)HMM predict
119Phosphoserine(CK1)HMM predict
124Phosphotyrosine(SRC)HMM predict
168N-linkedHMM predict
462Phosphotyrosine(Syk)HMM predict
487N-linkedHMM predict
503Phosphothreonine(PKA)HMM predict
526N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002298
  • Location:chr13 45598059-45654394
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 45656512 45656833 321 2278
CTCF CD4SISSRdata 45656512 45656833 321 2278
CTCF G2GSE9613 45656146 45656781 635 2069
Oct1 HelaGSE14283 45667736 45667810 74 13379
Pol2 GM12878GSE19551 45653859 45655022 1163 46
hScc1 BcellGSE12603 45656291 45656863 572 2183
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER MCF7GSE19013 45592147 45593108 961 5432
Fos K562GSE19551 45592169 45592848 679 5551
RARA MCF7GSE15244 45592356 45592923 567 5420
RARG MCF7GSE15244 45592356 45592923 567 5420
RARG MCF7GSE15244 45593702 45594437 735 3990
TFAP2C MCF7GSE21234 45593777 45594388 611 3977
VDR GM10855-UnstimGSE22484 45594922 45601184 6262 7
VDR GM10855-stimGSE22484 45595233 45600105 4872 391
VDR GM10861-UnstimGSE22484 45595158 45600391 5233 285
VDR GM10861-stimGSE22484 45594805 45600553 5748 381
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 45618046 45618483 437 0
CTCF CD4GSE12889 45632676 45632924 248 0
CTCF CD4SISSRdata 45632676 45632924 248 0
CTCF G2GSE9613 45598727 45599275 548 0
CTCF G2GSE9613 45632592 45632954 362 0
FOXA1 MCF7GSE15244 45614908 45615554 646 0
FoxA1 MCF7MACSdata 45615265 45615634 369 0
NFkBII GM12878GSE19485 45637114 45641756 4642 0
NFkBII GM12892GSE19485 45636654 45639708 3054 0
NFkBII GM18526GSE19485 45637205 45639364 2159 0
Oct1 H2O2-HelaGSE14283 45614764 45614795 31 0
Oct1 HelaGSE14283 45601631 45601669 38 0
Oct1 HelaGSE14283 45614763 45614798 35 0
Oct1 HelaGSE14283 45644627 45644705 78 0
RARA MCF7GSE15244 45607283 45607858 575 0
RARA MCF7GSE15244 45615122 45615554 432 0
RARG MCF7GSE15244 45598727 45599239 512 0
RARG MCF7GSE15244 45607283 45608590 1307 0
RARG MCF7GSE15244 45615048 45615554 506 0
STAT1 HeLaGSE12783 45632214 45633296 1082 0
STAT1 IFNSISSRdata 45632198 45633064 866 0
TAF k562GSE8489 45653224 45654888 1664 0
TFAP2C MCF7GSE21234 45607245 45607860 615 0
TFAP2C MCF7GSE21234 45640472 45640839 367 0
hScc1 BcellGSE12603 45598833 45599037 204 0
hScc1 CdLSGSE12603 45597946 45599588 1642 0
hScc1 CdLSGSE12603 45632556 45633027 471 0
hScc1 G2GSE9613 45598869 45599207 338 0
hScc1 G2GSE9613 45632556 45633027 471 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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