AutismKB 2.0

Annotation Detail for ARHGAP5


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Basic Information Top
Gene Symbol:ARHGAP5 ( GFI2,RhoGAP5,p190-B,p190BRhoGAP )
Gene Full Name: Rho GTPase activating protein 5
Band: 14q12
Quick LinksEntrez ID:394; OMIM: 602680; Uniprot ID:RHG05_HUMAN; ENSEMBL ID: ENSG00000100852; HGNC ID: 675
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
550Nitrated tyrosine.
765Phosphoserine.
968Phosphoserine.
1109Phosphotyrosine.
1115Phosphoserine.
1124Phosphoserine.
1129Phosphothreonine.
1138Phosphoserine.
1173Phosphoserine.
1176Phosphoserine.
1195Phosphoserine.
1202Phosphoserine.
1218Phosphoserine.
Location(AA) Modifications Resource
306Phosphotyrosine (InsR)Phospho.ELM 6.0
550Nitrated tyrosine.Swiss-Prot 53.0
Location(AA) Modification Resource
50SulfotyrosineHMM predict
50Phosphotyrosine(EGFR)HMM predict
55Phosphoserine(IKK)HMM predict
264Phosphothreonine(PKC)HMM predict
282Phosphothreonine(PKC)HMM predict
303SulfotyrosineHMM predict
306Phosphotyrosine(Syk)HMM predict
306SulfotyrosineHMM predict
306Phosphotyrosine(INSR)HMM predict
341Phosphothreonine(PKC)HMM predict
463Phosphotyrosine(Syk)HMM predict
465SulfotyrosineHMM predict
502SulfotyrosineHMM predict
507N-linkedHMM predict
528Phosphotyrosine(SRC)HMM predict
562N-linkedHMM predict
736Phosphothreonine(PKC)HMM predict
742N-linkedHMM predict
862Phosphoserine(CAMK2)HMM predict
887Phosphoserine(ATM)HMM predict
922Phosphoserine(ATM)HMM predict
928Phosphothreonine(PKA)HMM predict
981Phosphoserine(CK2)HMM predict
1074Phosphothreonine(PKC)HMM predict
1074Phosphothreonine(PKA)HMM predict
1090Phosphotyrosine(Syk)HMM predict
1090SulfotyrosineHMM predict
1090Phosphotyrosine(Abl)HMM predict
1090Phosphotyrosine(INSR)HMM predict
1103Phosphotyrosine(INSR)HMM predict
1108Phosphotyrosine(Syk)HMM predict
1108Phosphotyrosine(Jak)HMM predict
1108Phosphotyrosine(INSR)HMM predict
1108SulfotyrosineHMM predict
1123Phosphoserine(PKA)HMM predict
1126N-linkedHMM predict
1127N-linkedHMM predict
1201Phosphoserine(CDC2)HMM predict
1201Phosphoserine(MAPK)HMM predict
1216Phosphothreonine(CK2)HMM predict
1298N-linkedHMM predict
1304N-linkedHMM predict
1464O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001030055
  • Location:chr14 31616245-31698682
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me3 colorectalcancer 31614718 31615232 514 1271
H3ac HepG2E 31614682 31615569 887 1120
Oct1 HelaGSE14283 31601983 31602014 31 14247
hScc1 BcellGSE12603 31612531 31612891 360 3535
hScc1 CdLSGSE12603 31612458 31613032 574 3501
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 31707695 31707738 43 9034
Oct1 HelaGSE14283 31715307 31715338 31 16640
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 31692152 31692694 542 0
CTCF G2GSE9613 31616052 31616820 768 0
FoxA1 MCF7MACSdata 31673574 31674060 486 0
H3K4me3 colorectalcancer 31616667 31617981 1314 0
H3ac HepG2E 31616667 31619089 2422 0
Oct1 H2O2-HelaGSE14283 31673068 31673098 30 0
Oct1 H2O2-HelaGSE14283 31683302 31683360 58 0
Oct1 HelaGSE14283 31666356 31666395 39 0
Oct1 HelaGSE14283 31683299 31683365 66 0
Oct1 HelaGSE14283 31694952 31695034 82 0
RARA MCF7GSE15244 31641266 31641810 544 0
RARG MCF7GSE15244 31641266 31641674 408 0
p63 keratinocytesGSE17611 31624746 31625549 803 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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