Annotation Detail for LGALS2

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Basic Information Top

Gene Symbol:	LGALS2 ( HL14,MGC75071 )
Gene Full Name:	lectin, galactoside-binding, soluble, 2
Band:	22q13.1
Quick Links	Entrez ID:3957; OMIM: 150571; Uniprot ID:LEG2_HUMAN; ENSEMBL ID: ENSG00000100079; HGNC ID: 6562
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:0 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:3 results

No data

Location(AA)	Modification	Resource
59	Phosphoserine(IKK)	HMM predict
77	Phosphoserine(CDC2)	HMM predict
124	N-linked	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_006498
Location:chr22 36296199-36305969
strand:-

Upstream the gene:8 results
Downstream the gene:0 results
Inside the gene:4 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	36318529	36318778	249	12684
CTCF	CD4	SISSRdata	36318529	36318778	249	12684
CTCF	G2	GSE9613	36318626	36318886	260	12787
NFkBII	GM12878	GSE19485	36314403	36317251	2848	9858
NFkBII	GM12892	GSE19485	36314451	36315486	1035	8999
NFkBII	GM12892	GSE19485	36315915	36316875	960	10426
hScc1	Bcell	GSE12603	36318626	36318886	260	12787
hScc1	CdLS	GSE12603	36318626	36318886	260	12787

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ER	Breast-Cancer	GSE22609	36295909	36296704	795	0
ER	MCF7	GSE19013	36295823	36296758	935	0
RARA	MCF7	GSE15244	36295985	36297476	1491	0
RARG	MCF7	GSE15244	36295985	36297440	1455	0

Validated miRNA targets

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
17447	mRNA		chr22	36292420	36301911	136	mRNA	LGALS2	chr22	36290753	36300524	Sense/Antisense (SA) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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