AutismKB 2.0

Annotation Detail for LGALS3


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Basic Information Top
Gene Symbol:LGALS3 ( CBP35,GAL3,GALBP,GALIG,L31,LGALS2,MAC2 )
Gene Full Name: lectin, galactoside-binding, soluble, 3
Band: 14q22.3
Quick LinksEntrez ID:3958; OMIM: 153619; Uniprot ID:LEG3_HUMAN; ENSEMBL ID: ENSG00000131981; HGNC ID: 6563
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine (By similarity).
6Phosphoserine.
12Phosphoserine.
241Nuclear export signal (By similarity).
Location(AA) Modifications Resource
2N-acetylalanine (By similarity).Swiss-Prot 53.0
5Phosphoserine (CK1 alpha)Phospho.ELM 6.0
6Phosphoserine.Swiss-Prot 53.0
11Phosphoserine (CK1 alpha)Phospho.ELM 6.0
12Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
6Phosphoserine(CK1)HMM predict
12Phosphoserine(CK1)HMM predict
91O-linkedHMM predict
92O-linkedHMM predict
92Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002306
  • Location:chr14 54665624-54681899
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
RARA MCF7GSE15244 54658320 54659920 1600 6505
RARG MCF7GSE15244 54658576 54659920 1344 6377
RARG MCF7GSE15244 54664175 54664515 340 1280
Rb shRbSenescenceGSE19898 54659485 54659783 298 5991
p130 shRbSenescentGSE19898 54659694 54659914 220 5821
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 54665526 54665991 465 0
H3K4me3 colorectalcancer 54666435 54666992 557 0
RARA MCF7GSE15244 54666497 54666992 495 0
RARG MCF7GSE15244 54666459 54666992 533 0
RARG MCF7GSE15244 54667650 54668330 680 0
hScc1 BcellGSE12603 54665526 54666286 760 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-122 hsa-mir-122 18 20960104
hsa-miR-122 hsa-mir-122 18 20960104
hsa-miR-122* hsa-mir-122 18 20960104
hsa-miR-122* hsa-mir-122 18 20960104
hsa-miR-424 hsa-mir-424 X 17889671
hsa-miR-424 hsa-mir-424 X 17889671
hsa-miR-424* hsa-mir-424 X 17889671
hsa-miR-424* hsa-mir-424 X 17889671
hsa-miR-493 hsa-mir-493 14 20960104
hsa-miR-493 hsa-mir-493 14 20960104
hsa-miR-493* hsa-mir-493 14 20960104
hsa-miR-493* hsa-mir-493 14 20960104
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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