AutismKB 2.0

Annotation Detail for LGALS3BP


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Basic Information Top
Gene Symbol:LGALS3BP ( 90K,BTBD17B,MAC-2-BP )
Gene Full Name: lectin, galactoside-binding, soluble, 3 binding protein
Band: 17q25
Quick LinksEntrez ID:3959; OMIM: 600626; Uniprot ID:LG3BP_HUMAN; ENSEMBL ID: ENSG00000108679; HGNC ID: 6564
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
69N-linked (GlcNAc...).
125N-linked (GlcNAc...).
192N-linked (GlcNAc...).
362N-linked (GlcNAc...).
398N-linked (GlcNAc...).
551N-linked (GlcNAc...).
580N-linked (GlcNAc...).
Location(AA) Modifications Resource
69N-linked (GlcNAc...).Swiss-Prot 53.0
125N-linked (GlcNAc...).Swiss-Prot 53.0
192N-linked (GlcNAc...).Swiss-Prot 53.0
362N-linked (GlcNAc...).Swiss-Prot 53.0
398N-linked (GlcNAc...).Swiss-Prot 53.0
551N-linked (GlcNAc...).Swiss-Prot 53.0
580N-linked (GlcNAc...).Swiss-Prot 53.0
Location(AA) Modification Resource
69N-linkedHMM predict
125N-linkedHMM predict
130Phosphothreonine(PKA)HMM predict
191Phosphoserine(IKK)HMM predict
192N-linkedHMM predict
398N-linkedHMM predict
409Phosphotyrosine(INSR)HMM predict
411Phosphoserine(CDC2)HMM predict
419O-linkedHMM predict
428Phosphoserine(PKG)HMM predict
455SulfotyrosineHMM predict
456SulfotyrosineHMM predict
463Phosphothreonine(CDC2)HMM predict
551N-linkedHMM predict
556O-linkedHMM predict
558O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005567
  • Location:chr17 74478932-74487655
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 74487790 74488247 457 363
STAT1 IFNSISSRdata 74487257 74488483 1226 215
p130 QuiescentGSE19898 74487734 74488042 308 233
p130 SenescentGSE19898 74487883 74488181 298 377
p130 shRbQuiescentGSE19898 74487694 74488448 754 416
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 74461426 74461576 150 17432
CTCF G2GSE9613 74475212 74475550 338 3552
Oct1 H2O2-HelaGSE14283 74461812 74461846 34 17104
Oct1 H2O2-HelaGSE14283 74478875 74478905 30 43
Oct1 HelaGSE14283 74461812 74461846 34 17104
Oct1 HelaGSE14283 74478875 74478905 30 43
TFAP2C MCF7GSE21234 74463937 74464487 550 14721
TFAP2C MCF7GSE21234 74469963 74470497 534 8703
p130 QuiescentGSE19898 74459477 74459816 339 19286
p130 SenescentGSE19898 74459725 74460208 483 18966
p130 shRbQuiescentGSE19898 74459713 74460406 693 18873
p130 shRbSenescentGSE19898 74459515 74460138 623 19106
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 74479043 74479380 337 0
CTCF CD4SISSRdata 74479043 74479380 337 0
CTCF G2GSE9613 74478622 74480794 2172 0
H3ac HepG2E 74485446 74485982 536 0
STAT1 HeLaGSE12783 74484781 74489154 4373 0
TFAP2C MCF7GSE21234 74484479 74485457 978 0
USF1 HepG2E 74487469 74487823 354 0
hScc1 BcellGSE12603 74478622 74479564 942 0
hScc1 BcellGSE12603 74483501 74483862 361 0
hScc1 CdLSGSE12603 74478622 74479455 833 0
hScc1 G2GSE9613 74478659 74479666 1007 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018