AutismKB 2.0

Annotation Detail for LIG1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:LIG1 ( MGC117397,MGC130025 )
Gene Full Name: ligase I, DNA, ATP-dependent
Band: 19q13.33
Quick LinksEntrez ID:3978; OMIM: 126391; Uniprot ID:DNLI1_HUMAN; ENSEMBL ID: ENSG00000105486; HGNC ID: 6598
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
49Phosphoserine.
51Phosphoserine.
66Phosphoserine.
76Phosphoserine.
141Phosphoserine.
195Phosphothreonine.
201Phosphoserine.
229Phosphoserine.
230Phosphoserine.
233Phosphothreonine.
911Phosphoserine.
913Phosphoserine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000234
  • Location:chr19 53310514-53365371
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
LIN9 G0GSE7516 53364990 53366024 1034 136
P300 T30-glioblastomaGSE21026 53364984 53366037 1053 139
Rb GrowingGSE19898 53365281 53365789 508 164
Rb QuiescentGSE19898 53365220 53365810 590 144
Rb SenescentGSE19898 53365021 53365863 842 71
Rb shRbQuiescentGSE19898 53365441 53365686 245 192
Rb shRbSenescenceGSE19898 53365288 53365769 481 157
p130 QuiescentGSE19898 53365185 53365821 636 132
p130 SenescentGSE19898 53364900 53365858 958 8
p130 shRbQuiescentGSE19898 53364915 53366030 1115 101
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 53347547 53347907 360 0
CTCF CD4SISSRdata 53347547 53347907 360 0
CTCF HelaGSE12889 53347649 53347809 160 0
CTCF G2GSE9613 53365025 53365390 365 0
H3ac HepG2E 53364565 53364770 205 0
Oct1 H2O2-HelaGSE14283 53318908 53318935 27 0
Oct1 H2O2-HelaGSE14283 53327015 53327041 26 0
Oct1 H2O2-HelaGSE14283 53327821 53327849 28 0
Oct1 HelaGSE14283 53318907 53318938 31 0
Oct1 HelaGSE14283 53327013 53327044 31 0
Oct1 HelaGSE14283 53337250 53337290 40 0
P300 T30-glioblastomaGSE21026 53318737 53319501 764 0
TFAP2C MCF7GSE21234 53330419 53331602 1183 0
hScc1 BcellGSE12603 53322219 53322490 271 0
hScc1 BcellGSE12603 53325286 53325479 193 0
hScc1 BcellGSE12603 53334536 53334870 334 0
hScc1 BcellGSE12603 53364639 53365487 848 0
p130 shRbSenescentGSE19898 53364834 53365809 975 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
13415 EST chr19 53313515 53322682 162 mRNA LIG1 chr19 53310514 53365372Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved