AutismKB 2.0

Annotation Detail for LIG3


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Basic Information Top
Gene Symbol:LIG3 ( LIG2 )
Gene Full Name: ligase III, DNA, ATP-dependent
Band: 17q12
Quick LinksEntrez ID:3980; OMIM: 600940; Uniprot ID:DNLI3_HUMAN; ENSEMBL ID: ENSG00000005156; HGNC ID: 6600
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
209Phosphothreonine (By similarity).
210Phosphoserine.
227Phosphoserine.
242Phosphoserine.
316N6-acetyllysine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002311
  • Location:chr17 30331650-30354278
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FoxA1 MCF7MACSdata 30330893 30331066 173 671
H3K4me2 HCT116GSE10453 30330475 30331078 603 874
H3ac HepG2E 30330475 30331409 934 709
PHF8 Hs68plusFBSGSE20725 30330464 30332734 2270 52
RNAII Tamoxifen-MCF7GSE14664 30331193 30331292 99 408
TAF HelaGSE8489 30330584 30331300 716 709
TAF k562GSE8489 30330475 30331530 1055 648
USF1 HepG2E 30330548 30331448 900 653
hScc1 BcellGSE12603 30331372 30331713 341 108
p130 shRbSenescentGSE19898 30331321 30331812 491 84
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 30349344 30349683 339 0
CTCF CD4SISSRdata 30349344 30349683 339 0
CTCF JurkatGSE12889 30349395 30349541 146 0
CTCF G2GSE9613 30332029 30332567 538 0
CTCF G2GSE9613 30349296 30350572 1276 0
H3ac HepG2E 30332384 30333350 966 0
Myc K562GSE19551 30331218 30332639 1421 0
Myc hESGSE17917 30331672 30331875 203 0
Oct1 HelaGSE14283 30340326 30340355 29 0
Oct1 HelaGSE14283 30341318 30341347 29 0
PHF8 293TGSE20725 30331122 30332411 1289 0
PHF8 HeLaGSE20725 30331127 30332489 1362 0
PHF8 Hs68minusFBSGSE20725 30330981 30332647 1666 0
Rb SenescentGSE19898 30332021 30332258 237 0
USF2 HepG2E 30337756 30338057 301 0
hScc1 BcellGSE12603 30332199 30332526 327 0
hScc1 BcellGSE12603 30349263 30349904 641 0
hScc1 BcellGSE12603 30350380 30350572 192 0
hScc1 CdLSGSE12603 30349186 30349940 754 0
hScc1 G2GSE9613 30349296 30350572 1276 0
p130 QuiescentGSE19898 30331979 30332540 561 0
p130 SenescentGSE19898 30331953 30332532 579 0
p130 shRbQuiescentGSE19898 30332061 30332683 622 0
p130 shRbSenescentGSE19898 30332031 30332733 702 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018