AutismKB 2.0

Annotation Detail for LLGL2


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Basic Information Top
Gene Symbol:LLGL2 ( HGL,LGL2 )
Gene Full Name: lethal giant larvae homolog 2 (Drosophila)
Band: 17q25.1
Quick LinksEntrez ID:3993; OMIM: NA; Uniprot ID:L2GL2_HUMAN; ENSEMBL ID: ENSG00000073350; HGNC ID: 6629
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
653Phosphoserine.
1015Phosphoserine.
Location(AA) Modifications Resource
664Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
24N-linkedHMM predict
96Phosphoserine(CK1)HMM predict
128O-linkedHMM predict
250Phosphoserine(CK1)HMM predict
427O-linkedHMM predict
429O-linkedHMM predict
478N-linkedHMM predict
499Phosphotyrosine(Syk)HMM predict
499PhosphotyrosineHMM predict
518Phosphotyrosine(Syk)HMM predict
660Phosphoserine(PKG)HMM predict
823Phosphothreonine(PKC)HMM predict
847Phosphoserine(PKG)HMM predict
914Phosphoserine(MAPK)HMM predict
961Phosphoserine(PKG)HMM predict
961Phosphoserine(IKK)HMM predict
961O-linkedHMM predict
965Phosphoserine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001015002
  • Location:chr17 71033377-71072398
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 BcellGSE12603 71032564 71033495 931 348
hScc1 CdLSGSE12603 71032614 71033495 881 323
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 71033160 71033807 647 0
CTCF G2GSE9613 71043075 71043228 153 0
CTCF G2GSE9613 71066282 71066490 208 0
ER E2-MCF7GSE14664 71050057 71050091 34 0
ER Fulvestrant-MCF7GSE14664 71036374 71036416 42 0
ER Fulvestrant-MCF7GSE14664 71050054 71050088 34 0
ER MCF7GSE19013 71056385 71058159 1774 0
ER MCF7GSE19013 71064623 71065712 1089 0
Fos K562GSE19551 71064696 71065201 505 0
Oct1 H2O2-HelaGSE14283 71069184 71069213 29 0
Oct1 HelaGSE14283 71036373 71036423 50 0
Oct1 HelaGSE14283 71050053 71050088 35 0
Oct1 HelaGSE14283 71069141 71069213 72 0
RARA MCF7GSE15244 71064864 71065866 1002 0
RARG MCF7GSE15244 71064864 71065650 786 0
TFAP2C MCF7GSE21234 71056478 71058276 1798 0
TFAP2C MCF7GSE21234 71064510 71066574 2064 0
hScc1 BcellGSE12603 71048086 71048684 598 0
hScc1 BcellGSE12603 71066132 71066490 358 0
hScc1 BcellGSE12603 71070766 71071079 313 0
p63 keratinocytesGSE17611 71047995 71048751 756 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018