AutismKB 2.0

Annotation Detail for SPRED3


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Basic Information Top
Gene Symbol:SPRED3 ( Eve-3 )
Gene Full Name: sprouty-related, EVH1 domain containing 3
Band: 19q13
Quick LinksEntrez ID:399473; OMIM: 609293; Uniprot ID:SPRE3_HUMAN; ENSEMBL ID: ENSG00000188766; HGNC ID: 31041
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
14Phosphoserine(CK1)HMM predict
119Phosphothreonine(MAPK)HMM predict
127Phosphoserine(CK1)HMM predict
128PhosphoserineHMM predict
128Phosphoserine(CDC2)HMM predict
130Phosphoserine(ATM)HMM predict
130Phosphoserine(CK1)HMM predict
133O-linkedHMM predict
136Phosphothreonine(MAPK)HMM predict
136PhosphothreonineHMM predict
148Phosphoserine(CK1)HMM predict
149Phosphoserine(CK1)HMM predict
151Phosphoserine(CK1)HMM predict
157PhosphothreonineHMM predict
157Phosphothreonine(CDK)HMM predict
157Phosphothreonine(MAPK)HMM predict
160O-linkedHMM predict
168O-linkedHMM predict
173O-linkedHMM predict
178O-linkedHMM predict
179Phosphothreonine(MAPK)HMM predict
186Phosphoserine(PKG)HMM predict
186Phosphoserine(PKA)HMM predict
186Phosphoserine(PKB)HMM predict
187Phosphoserine(PKG)HMM predict
187Phosphoserine(PKA)HMM predict
187Phosphoserine(PKA)HMM predict
190Phosphoserine(PKA)HMM predict
204O-linkedHMM predict
281O-linkedHMM predict
331S-palmitoylHMM predict
340Phosphotyrosine(INSR)HMM predict
379S-palmitoylHMM predict
382S-palmitoylHMM predict
401S-palmitoylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001039616
  • Location:chr19 43572778-43576955
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K27me3 colorectalcancer 43573184 43574497 1313 0
H3K27me3 colorectalcancer 43576100 43576776 676 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018