AutismKB 2.0

Annotation Detail for LRP4


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Basic Information Top
Gene Symbol:LRP4 ( CLSS,KIAA0816,LRP-4,LRP10,MEGF7 )
Gene Full Name: low density lipoprotein receptor-related protein 4
Band: 11p11.2
Quick LinksEntrez ID:4038; OMIM: 604270; Uniprot ID:LRP4_HUMAN; ENSEMBL ID: ENSG00000134569; HGNC ID: 6696
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
264N-linked (GlcNAc...) (Potential).
498N-linked (GlcNAc...) (Potential).
719N-linked (GlcNAc...) (Potential).
901N-linked (GlcNAc...) (Potential).
1077N-linked (GlcNAc...) (Potential).
1415N-linked (GlcNAc...) (Potential).
1467N-linked (GlcNAc...) (Potential).
1769Endocytosis signal (Potential).
1887Phosphoserine (By similarity).
Location(AA) Modifications Resource
309N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
543N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
764N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
946N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1122N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1460N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1512N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
31Phosphoserine(CK1)HMM predict
31Phosphoserine(PKB)HMM predict
31Phosphoserine(IKK)HMM predict
37Phosphoserine(CDC2)HMM predict
37Phosphoserine(CDK)HMM predict
39O-linkedHMM predict
39Phosphoserine(ATM)HMM predict
43O-linkedHMM predict
60MethylarginineHMM predict
229O-linkedHMM predict
268Phosphoserine(CK2)HMM predict
309N-linkedHMM predict
451Phosphoserine(ATM)HMM predict
543N-linkedHMM predict
546N-linkedHMM predict
621Phosphothreonine(MAPK)HMM predict
764N-linkedHMM predict
766O-linkedHMM predict
801Phosphoserine(PKG)HMM predict
801Phosphoserine(CAMK2)HMM predict
808Phosphoserine(ATM)HMM predict
917Phosphotyrosine(Jak)HMM predict
926Phosphoserine(CDC2)HMM predict
946N-linkedHMM predict
951N-linkedHMM predict
1067N-linkedHMM predict
1122N-linkedHMM predict
1127N-linkedHMM predict
1158Phosphoserine(ATM)HMM predict
1158Phosphoserine(CK2)HMM predict
1377O-linkedHMM predict
1413Phosphoserine(PKG)HMM predict
1413Phosphoserine(CAMK2)HMM predict
1417Phosphoserine(ATM)HMM predict
1460N-linkedHMM predict
1462Phosphoserine(CK2)HMM predict
1463N-linkedHMM predict
1512N-linkedHMM predict
1513N-linkedHMM predict
1529Phosphotyrosine(Jak)HMM predict
1707Phosphothreonine(PKC)HMM predict
1713Phosphoserine(IKK)HMM predict
1713Phosphoserine(CDK)HMM predict
1719Phosphothreonine(MAPK)HMM predict
1719O-linkedHMM predict
1719PhosphothreonineHMM predict
1723O-linkedHMM predict
1734Phosphoserine(PKG)HMM predict
1806N-linkedHMM predict
1809Phosphotyrosine(INSR)HMM predict
1811N-linkedHMM predict
1846N-linkedHMM predict
1847Phosphotyrosine(Syk)HMM predict
1901Phosphoserine(IKK)HMM predict
1916Phosphoserine(CK2)HMM predict
1916Phosphoserine(IKK)HMM predict
1920Phosphoserine(CK1)HMM predict
1926Phosphothreonine(CDK)HMM predict
1926Phosphothreonine(CDC2)HMM predict
1926Phosphothreonine(MAPK)HMM predict
1932Phosphoserine(PKC)HMM predict
1932Phosphoserine(IKK)HMM predict
1932Phosphoserine(CK1)HMM predict
1932Phosphoserine(PKB)HMM predict
1945Phosphoserine(CK2)HMM predict
1945Phosphoserine(CK1)HMM predict
1945Phosphoserine(PKA)HMM predict
1945Phosphoserine(PKG)HMM predict
1946Phosphoserine(PKG)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002334
  • Location:chr11 46834994-46896748
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 46897964 46898285 321 1376
CTCF CD4SISSRdata 46897964 46898285 321 1376
FOXA1 MCF7GSE15244 46897171 46897364 193 519
P300 T30-glioblastomaGSE21026 46898536 46899587 1051 2313
hScc1 BcellGSE12603 46897996 46898352 356 1426
hScc1 CdLSGSE12603 46897927 46898352 425 1391
hScc1 G2GSE9613 46897964 46898352 388 1410
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 46867755 46868018 263 0
CTCF CD4SISSRdata 46867755 46868018 263 0
ER E2-MCF7GSE14664 46843515 46843547 32 0
ER E2-MCF7GSE14664 46846576 46846608 32 0
H3ac HepG2E 46894605 46895943 1338 0
Myc K562GSE19551 46864227 46864754 527 0
NRSF pAbJurkat 46859499 46859694 195 0
Oct1 H2O2-HelaGSE14283 46839397 46839438 41 0
Oct1 HelaGSE14283 46839404 46839432 28 0
Oct1 HelaGSE14283 46857162 46857198 36 0
STAT1 IFNSISSRdata 46867792 46868123 331 0
hScc1 BcellGSE12603 46867493 46868401 908 0
hScc1 BcellGSE12603 46873172 46873536 364 0
hScc1 BcellGSE12603 46876614 46877038 424 0
hScc1 BcellGSE12603 46889564 46889862 298 0
hScc1 BcellGSE12603 46896019 46896914 895 0
hScc1 CdLSGSE12603 46867112 46868327 1215 0
hScc1 CdLSGSE12603 46896087 46896653 566 0
hScc1 G2GSE9613 46867493 46868563 1070 0
hScc1 G2GSE9613 46896124 46896653 529 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
4389 HTC chr11 46824553 46852518 354 mRNA LRP4 chr11 46834994 46896749Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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