AutismKB 2.0

Annotation Detail for LRPAP1


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Basic Information Top
Gene Symbol:LRPAP1 ( A2MRAP,A2RAP,HBP44,MGC138272,MRAP,RAP )
Gene Full Name: low density lipoprotein receptor-related protein associated protein 1
Band: 4p16.3
Quick LinksEntrez ID:4043; OMIM: 104225; Uniprot ID:AMRP_HUMAN; ENSEMBL ID: ENSG00000163956; HGNC ID: 6701
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
268N-linked (GlcNAc...).
287N6-acetyllysine.
357Prevents secretion from ER (Potential).
Location(AA) Modifications Resource
268N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
8PhosphoserineHMM predict
45Phosphoserine(CDC2)HMM predict
45PhosphoserineHMM predict
50Phosphoserine(PKA)HMM predict
50Phosphoserine(PKG)HMM predict
134Phosphothreonine(PKC)HMM predict
139Phosphoserine(CK1)HMM predict
242Phosphoserine(PKA)HMM predict
242Phosphoserine(PKG)HMM predict
246Phosphotyrosine(Syk)HMM predict
268N-linkedHMM predict
270Phosphothreonine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002337
  • Location:chr4 3484092-3503941
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 3503539 3504564 1025 110
CTCF G2GSE9613 3506923 3507596 673 3318
CTCF G2GSE9613 3507952 3508271 319 4170
CTCF G2GSE9613 3511923 3512141 218 8091
CTCF G2GSE9613 3516791 3517010 219 12959
CTCF G2GSE9613 3520483 3521131 648 16866
CTCF G2GSE9613 3522993 3523635 642 19373
ETS1 JurkatGSE17954 3503651 3504425 774 97
P300 T0-glioblastomaGSE21026 3503810 3504226 416 77
P300 T30-glioblastomaGSE21026 3503686 3504323 637 63
PHF8 Hs68minusFBSGSE20725 3503585 3504346 761 24
hScc1 BcellGSE12603 3511923 3512141 218 8091
hScc1 G2GSE9613 3520402 3521058 656 16789
p130 shRbSenescentGSE19898 3504114 3504296 182 264
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 3476512 3477270 758 7202
CTCF G2GSE9613 3480377 3481449 1072 3180
CTCF G2GSE9613 3482105 3482511 406 1785
CTCF G2GSE9613 3483203 3484688 1485 147
Oct1 HelaGSE14283 3481370 3481403 33 2706
hScc1 BcellGSE12603 3476717 3477308 591 7080
hScc1 BcellGSE12603 3482105 3482434 329 1823
hScc1 BcellGSE12603 3483014 3483550 536 811
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 3485290 3487494 2204 0
CTCF G2GSE9613 3487738 3490844 3106 0
CTCF G2GSE9613 3491290 3491463 173 0
CTCF G2GSE9613 3492248 3493346 1098 0
CTCF G2GSE9613 3493663 3496771 3108 0
CTCF G2GSE9613 3498194 3498862 668 0
CTCF G2GSE9613 3499653 3500552 899 0
CTCF G2GSE9613 3500888 3502738 1850 0
H3K4me3 colorectalcancer 3503204 3503443 239 0
H3ac HepG2E 3501365 3502136 771 0
NFkBII GM15510GSE19485 3502945 3504548 1603 0
Oct1 HelaGSE14283 3494662 3494703 41 0
PHF8 HeLaGSE20725 3503310 3504497 1187 0
PHF8 Hs68plusFBSGSE20725 3503272 3504382 1110 0
Pol2 GM12878GSE19551 3503715 3504026 311 0
Rb GrowingGSE19898 3503858 3503972 114 0
Rb SenescentGSE19898 3503631 3504107 476 0
Rb shRbQuiescentGSE19898 3490783 3491090 307 0
Rb shRbQuiescentGSE19898 3500438 3500595 157 0
TFAP2C MCF7GSE21234 3501977 3502810 833 0
hScc1 BcellGSE12603 3487242 3488503 1261 0
hScc1 BcellGSE12603 3488838 3490668 1830 0
hScc1 BcellGSE12603 3498596 3498969 373 0
hScc1 BcellGSE12603 3499877 3500224 347 0
hScc1 BcellGSE12603 3503204 3503961 757 0
hScc1 G2GSE9613 3486000 3486914 914 0
hScc1 G2GSE9613 3493992 3494693 701 0
p130 QuiescentGSE19898 3503720 3503975 255 0
p130 SenescentGSE19898 3503719 3504014 295 0
p130 shRbSenescentGSE19898 3503750 3504058 308 0
p63 keratinocytesGSE17611 3502815 3503766 951 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-23a hsa-mir-23a 19 20553585
hsa-miR-23a hsa-mir-23a 19 20553585
hsa-miR-23a* hsa-mir-23a 19 20553585
hsa-miR-23a* hsa-mir-23a 19 20553585
hsa-miR-27a hsa-mir-27a 19 20553585
hsa-miR-27a hsa-mir-27a 19 20553585
hsa-miR-27a* hsa-mir-27a 19 20553585
hsa-miR-27a* hsa-mir-27a 19 20553585
hsa-miR-29b hsa-mir-29b-1 7 19509302
hsa-miR-29b hsa-mir-29b-2 1 19509302
hsa-miR-29b hsa-mir-29b-1 7 19509302
hsa-miR-29b hsa-mir-29b-2 1 19509302
hsa-miR-539 hsa-mir-539 14 16973894
hsa-miR-539 hsa-mir-539 14 16973894
hsa-miR-802 hsa-mir-802 21 16973894
hsa-miR-802 hsa-mir-802 21 16973894
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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