AutismKB 2.0

Annotation Detail for LSS


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Basic Information Top
Gene Symbol:LSS ( FLJ25486,FLJ35015,FLJ39450,FLJ46393,OSC )
Gene Full Name: lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
Band: 21q22.3
Quick LinksEntrez ID:4047; OMIM: 600909; Uniprot ID:ERG7_HUMAN; ENSEMBL ID: ENSG00000160285; HGNC ID: 6708
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
16Phosphothreonine(PKC)HMM predict
249Phosphoserine(PKG)HMM predict
382N-linkedHMM predict
421Phosphoserine(ATM)HMM predict
433Phosphotyrosine(Syk)HMM predict
516N-linkedHMM predict
576Phosphoserine(IKK)HMM predict
635Phosphoserine(CK2)HMM predict
718ArginineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001001438
  • Location:chr21 46432788-46473118
  • strand:-
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 46432713 46433570 857 0
Fos K562GSE19551 46432547 46433323 776 0
RARA MCF7GSE15244 46432676 46433747 1071 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018