AutismKB 2.0

Annotation Detail for LTBP2


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Basic Information Top
Gene Symbol:LTBP2 ( C14orf141,GLC3D,LTBP3,MSTP031 )
Gene Full Name: latent transforming growth factor beta binding protein 2
Band: 14q24.3
Quick LinksEntrez ID:4053; OMIM: 602091; Uniprot ID:LTBP2_HUMAN; ENSEMBL ID: ENSG00000119681; HGNC ID: 6715
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
181N-linked (GlcNAc...) (Potential).
343N-linked (GlcNAc...) (Potential).
377Cell attachment site (Potential).
421N-linked (GlcNAc...) (Potential).
506Phosphoserine (By similarity).
616N-linked (GlcNAc...) (Potential).
811N-linked (GlcNAc...) (Potential).
1170N-linked (GlcNAc...) (Potential).
1309N-linked (GlcNAc...) (Potential).
1430N-linked (GlcNAc...) (Potential).
1568N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
181N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
343N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
421N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
616N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
811N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1170N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1309N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1430N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1568N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
9PhosphoserineHMM predict
9Phosphoserine(CDC2)HMM predict
94Phosphoserine(CDC2)HMM predict
99Phosphothreonine(PKA)HMM predict
99Phosphothreonine(PKC)HMM predict
107Phosphoserine(PKA)HMM predict
107PhosphoserineHMM predict
112O-linkedHMM predict
121Phosphothreonine(PKC)HMM predict
121O-linkedHMM predict
125Phosphothreonine(PKA)HMM predict
125Phosphothreonine(CDK)HMM predict
147Phosphothreonine(MAPK)HMM predict
147Phosphothreonine(CDK)HMM predict
151O-linkedHMM predict
157Phosphothreonine(CDK)HMM predict
157Phosphothreonine(CDC2)HMM predict
157Phosphothreonine(MAPK)HMM predict
160MethylarginineHMM predict
162MethylarginineHMM predict
181N-linkedHMM predict
184N-linkedHMM predict
250Phosphoserine(PKG)HMM predict
267Phosphoserine(IKK)HMM predict
273Phosphoserine(IKK)HMM predict
283Phosphoserine(ATM)HMM predict
288Phosphoserine(ATM)HMM predict
303O-linkedHMM predict
305O-linkedHMM predict
308Phosphoserine(IKK)HMM predict
308O-linkedHMM predict
308Phosphoserine(ATM)HMM predict
312Phosphoserine(IKK)HMM predict
404S-palmitoylHMM predict
421N-linkedHMM predict
470N-linkedHMM predict
518Phosphoserine(CDK)HMM predict
518Phosphoserine(CDC2)HMM predict
589S-palmitoylHMM predict
598Phosphoserine(CDC2)HMM predict
598Phosphoserine(MAPK)HMM predict
616N-linkedHMM predict
697S-palmitoylHMM predict
698S-palmitoylHMM predict
730Phosphotyrosine(Abl)HMM predict
798O-linkedHMM predict
800O-linkedHMM predict
811N-linkedHMM predict
873Phosphoserine(MAPK)HMM predict
881Phosphoserine(ATM)HMM predict
918O-linkedHMM predict
921O-linkedHMM predict
988Phosphoserine(MAPK)HMM predict
988Phosphoserine(CDC2)HMM predict
992Phosphotyrosine(INSR)HMM predict
1007Phosphoserine(IKK)HMM predict
1040Phosphotyrosine(Syk)HMM predict
1043Phosphothreonine(CK2)HMM predict
1060O-linkedHMM predict
1105O-linkedHMM predict
1144Phosphoserine(IKK)HMM predict
1170N-linkedHMM predict
1203S-palmitoylHMM predict
1266Phosphotyrosine(INSR)HMM predict
1266SulfotyrosineHMM predict
1289S-palmitoylHMM predict
1309N-linkedHMM predict
1379Phosphotyrosine(Syk)HMM predict
1379SulfotyrosineHMM predict
1397Phosphoserine(IKK)HMM predict
1430N-linkedHMM predict
1469Phosphotyrosine(Jak)HMM predict
1469Phosphotyrosine(INSR)HMM predict
1568N-linkedHMM predict
1572PhosphoserineHMM predict
1657SulfotyrosineHMM predict
1702Phosphothreonine(MAPK)HMM predict
1707Phosphoserine(CDC2)HMM predict
1804S-farnesylHMM predict
1807GlycineHMM predict
1820LysineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000428
  • Location:chr14 74034641-74148786
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 74148952 74149339 387 359
CTCF G2GSE9613 74153602 74153823 221 4926
CTCF G2GSE9613 74160839 74160973 134 12120
CTCF G2GSE9613 74167793 74168073 280 19147
Fos K562GSE19551 74152893 74153431 538 4376
Gata2 K562GSE18868 74156925 74157615 690 8484
KLF4 hESGSE17917 74167677 74168116 439 19110
NFkBII GM12878GSE19485 74150774 74152221 1447 2711
P300 T30-glioblastomaGSE21026 74155745 74157969 2224 8071
RARG MCF7GSE15244 74151159 74151962 803 2774
TFAP2C MCF7GSE21234 74151132 74151760 628 2660
hScc1 BcellGSE12603 74148952 74149339 387 359
hScc1 BcellGSE12603 74152118 74152592 474 3569
hScc1 BcellGSE12603 74167015 74167161 146 18302
hScc1 CdLSGSE12603 74148553 74149339 786 160
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 74107902 74109896 1994 0
CTCF CD4GSE12889 74038668 74038878 210 0
CTCF CD4GSE12889 74145392 74145924 532 0
CTCF CD4SISSRdata 74038668 74038878 210 0
CTCF CD4SISSRdata 74145392 74145924 532 0
CTCF G2GSE9613 74037138 74037959 821 0
CTCF G2GSE9613 74038481 74039295 814 0
CTCF G2GSE9613 74042363 74042557 194 0
CTCF G2GSE9613 74045119 74045334 215 0
CTCF G2GSE9613 74046217 74046531 314 0
CTCF G2GSE9613 74046925 74047838 913 0
CTCF G2GSE9613 74052635 74053063 428 0
CTCF G2GSE9613 74068825 74069099 274 0
CTCF G2GSE9613 74078815 74079066 251 0
CTCF G2GSE9613 74083254 74083464 210 0
CTCF G2GSE9613 74085566 74085736 170 0
CTCF G2GSE9613 74086129 74086265 136 0
CTCF G2GSE9613 74103310 74103708 398 0
CTCF G2GSE9613 74114455 74115270 815 0
CTCF G2GSE9613 74126043 74126334 291 0
CTCF G2GSE9613 74132851 74133569 718 0
CTCF G2GSE9613 74145499 74146029 530 0
CTCF G2GSE9613 74147945 74148375 430 0
NRSF JurkatGSE13047 74083808 74084628 820 0
NRSF-mono JurkatQuESTdata 74083807 74084556 749 0
NRSF-poly JurkatQuESTdata 74083942 74084492 550 0
Oct1 H2O2-HelaGSE14283 74057181 74057223 42 0
Oct1 H2O2-HelaGSE14283 74136319 74136348 29 0
Oct1 HelaGSE14283 74052125 74052159 34 0
Oct1 HelaGSE14283 74057179 74057223 44 0
P300 T0-glioblastomaGSE21026 74051293 74051722 429 0
P300 T30-glioblastomaGSE21026 74107827 74109904 2077 0
RARA MCF7GSE15244 74037284 74037619 335 0
TFAP2C MCF7GSE21234 74102719 74103812 1093 0
hScc1 BcellGSE12603 74085388 74085667 279 0
hScc1 BcellGSE12603 74120903 74121239 336 0
hScc1 BcellGSE12603 74145249 74145989 740 0
hScc1 BcellGSE12603 74147156 74147508 352 0
hScc1 CdLSGSE12603 74145249 74145872 623 0
p130 QuiescentGSE19898 74108301 74109063 762 0
p63 keratinocytesGSE17611 74054353 74055422 1069 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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