AutismKB 2.0

Annotation Detail for LUM


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Basic Information Top
Gene Symbol:LUM ( LDC,SLRR2D )
Gene Full Name: lumican
Band: 12q21.33
Quick LinksEntrez ID:4060; OMIM: 600616; Uniprot ID:LUM_HUMAN; ENSEMBL ID: ENSG00000139329; HGNC ID: 6724
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
19Pyrrolidone carboxylic acid.
20Sulfotyrosine (By similarity).
21Sulfotyrosine (By similarity).
23Sulfotyrosine (By similarity).
30Sulfotyrosine (By similarity).
88N-linked (GlcNAc...) (keratan sulfate).
127N-linked (GlcNAc...) (keratan sulfate)
160N-linked (GlcNAc...) (keratan sulfate).
252N-linked (GlcNAc...) (keratan sulfate)
Location(AA) Modifications Resource
88N-linked (GlcNAc...) (keratan sulfate).Swiss-Prot 53.0
127N-linked (GlcNAc...) (keratan sulfate)(Potential).Swiss-Prot 53.0
160N-linked (GlcNAc...) (keratan sulfate).Swiss-Prot 53.0
252N-linked (GlcNAc...) (keratan sulfate)(Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
20SulfotyrosineHMM predict
23SulfotyrosineHMM predict
70Phosphotyrosine(Jak)HMM predict
88N-linkedHMM predict
127N-linkedHMM predict
160N-linkedHMM predict
188Phosphotyrosine(INSR)HMM predict
224Phosphotyrosine(Jak)HMM predict
279SulfotyrosineHMM predict
280Phosphotyrosine(Syk)HMM predict
335ValineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002345
  • Location:chr12 90021363-90029672
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 90044656 90044729 73 15020
p63 keratinocytesGSE17611 90036764 90037743 979 7581
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 90016843 90017086 243 4399
P300 T30-glioblastomaGSE21026 90016633 90017509 876 4293
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 90027071 90027271 200 0
CTCF CD4SISSRdata 90027071 90027271 200 0
CTCF JurkatGSE12889 90026953 90027247 294 0
hScc1 BcellGSE12603 90026897 90027317 420 0
hScc1 CdLSGSE12603 90026831 90027430 599 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018