Annotation Detail for MBNL1

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Basic Information Top

Gene Symbol:	MBNL1 ( DKFZp686P06174,EXP,EXP35,EXP40,EXP42,KIAA0428,MBNL )
Gene Full Name:	muscleblind-like (Drosophila)
Band:	3q25.1-q25.2
Quick Links	Entrez ID:4154; OMIM: 606516; Uniprot ID:MBNL1_HUMAN; ENSEMBL ID: ENSG00000152601; HGNC ID: 6923
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

No data

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CBP	T30-glioblastoma	GSE21026	153458538	153459765	1227	9367
FOXA1	MCF7	GSE15244	153458966	153459290	324	9391
H3K4me2	HCT116	GSE10453	153467259	153468633	1374	573
H3K4me3	colorectal	cancer	153467804	153468670	866	282
Oct1	Hela	GSE14283	153465573	153465604	31	2930
P300	T30-glioblastoma	GSE21026	153458461	153459944	1483	9316
RARA	MCF7	GSE15244	153458930	153459359	429	9374
RARG	MCF7	GSE15244	153458930	153459250	320	9429
RARG	MCF7	GSE15244	153467360	153468925	1565	376
p63	keratinocytes	GSE17611	153458795	153459560	765	9341

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	G2	GSE9613	153468925	153469347	422
CTCF	G2	GSE9613	153469632	153469937	305
FOXA1	MCF7	GSE15244	153498863	153499528	665
Fos	K562	GSE19551	153499189	153499936	747
H3K4me2	HCT116	GSE10453	153498805	153499492	687
H3K4me3	colorectal	cancer	153470291	153471231	940
H3ac	HepG2	E	153469725	153471298	1573
H3ac	HepG2	E	153498805	153499662	857
NRSF	mAb	Jurkat	153496058	153497704	1646
Oct1	H2O2-Hela	GSE14283	153478199	153478227	28
Pol2	GM12878	GSE19551	153468817	153470339	1522
RARA	MCF7	GSE15244	153498770	153500333	1563
RARG	MCF7	GSE15244	153498841	153499630	789
TAF	k562	GSE8489	153470046	153472261	2215
USF2	HepG2	E	153498863	153499662	799
hScc1	Bcell	GSE12603	153468854	153470150	1296
hScc1	CdLS	GSE12603	153468854	153470964	2110
hScc1	G2	GSE9613	153469632	153470010	378

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7b	hsa-let-7b	22	18668040
hsa-let-7b*	hsa-let-7b	22	18668040
hsa-miR-1	hsa-mir-1-2	18	18668040
hsa-miR-1	hsa-mir-1-1	20	18668040
hsa-miR-155	hsa-mir-155	21	18668040
hsa-miR-155*	hsa-mir-155	21	18668040
hsa-miR-16	hsa-mir-16-1	13	18668040
hsa-miR-16	hsa-mir-16-2	3	18668040
hsa-miR-30a	hsa-mir-30a	6	18668040
hsa-miR-30a*	hsa-mir-30a	6	18668040
hsa-miR-30b	hsa-mir-30b	8	18668040
hsa-miR-30b*	hsa-mir-30b	8	18668040
hsa-miR-30c	hsa-mir-30c-2	6	18668040
hsa-miR-30c	hsa-mir-30c-1	1	18668040
hsa-miR-30c-1*	hsa-mir-30c-1	1	18668040
hsa-miR-30c-2*	hsa-mir-30c-2	6	18668040
hsa-miR-30d	hsa-mir-30d	8	18668040
hsa-miR-30d*	hsa-mir-30d	8	18668040
hsa-miR-30e	hsa-mir-30e	1	18668040
hsa-miR-30e*	hsa-mir-30e	1	18668040

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
1245	Unknown	pSILAC	miR-30	MBNL1	down 50-25%	18668040
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000152601		n_a	n_a	n_a	"epithelium, lymphoblast, lymphocyte, muscle cell"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
18864	mRNA	MBNL1	chr3	153468526	153666266	369	EST	MBNL1	chr3	153468526	153468895	Sense/Antisense (SA) pairs

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018