AutismKB 2.0

Annotation Detail for MBP


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Basic Information Top
Gene Symbol:MBP ( MGC99675 )
Gene Full Name: myelin basic protein
Band: 18q23
Quick LinksEntrez ID:4155; OMIM: 159430; Uniprot ID:MBP_HUMAN; ENSEMBL ID: ENSG00000197971; HGNC ID: 6925
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
96Phosphoserine.
141Phosphoserine (By similarity).
146Phosphoserine (By similarity).
159Citrulline; in form C8.
165Citrulline; in form C8.
169Phosphothreonine (By similarity).
174Phosphoserine (By similarity).
203Phosphotyrosine (By similarity).
205Phosphoserine (By similarity).
229Phosphothreonine (By similarity).
232Phosphothreonine (By similarity).
237Deamidated glutamine (By similarity).
241Omega-N-methylarginine; alternate.
241Symmetric dimethylarginine; alternate.
249Phosphoserine (By similarity).
256Citrulline; in form C8.
264Citrulline; in form C8.
281Deamidated glutamine (By similarity).
293Citrulline; in form C8.
295Phosphoserine (By similarity).
299Phosphoserine (By similarity).
304Citrulline; in form C8.
Location(AA) Modifications Resource
96Phosphoserine.Swiss-Prot 53.0
96PhosphoserinePhospho.ELM 6.0
121O-linkedOGlycBase6.0
124O-linkedOGlycBase6.0
141Phosphoserine (By similarity).Swiss-Prot 53.0
146Phosphoserine (By similarity).Swiss-Prot 53.0
159Citrulline; in form C8.Swiss-Prot 53.0
165Citrulline; in form C8.Swiss-Prot 53.0
169Phosphothreonine (By similarity).Swiss-Prot 53.0
174Phosphoserine (By similarity).Swiss-Prot 53.0
205Phosphoserine (By similarity).Swiss-Prot 53.0
229Phosphothreonine (By similarity).Swiss-Prot 53.0
232Phosphothreonine (MAPK1;MAPK3)Phospho.ELM 6.0
232Phosphothreonine (By similarity).Swiss-Prot 53.0
237Deamidated glutamine (By similarity).Swiss-Prot 53.0
241Symmetric dimethylarginine; alternate.Swiss-Prot 53.0
241Omega-N-methylarginine; alternate.Swiss-Prot 53.0
249Phosphoserine (By similarity).Swiss-Prot 53.0
256Citrulline; in form C8.Swiss-Prot 53.0
264Citrulline; in form C8.Swiss-Prot 53.0
281Deamidated glutamine (By similarity).Swiss-Prot 53.0
293Citrulline; in form C8.Swiss-Prot 53.0
295Phosphoserine (By similarity).Swiss-Prot 53.0
299Phosphoserine (By similarity).Swiss-Prot 53.0
299Phosphoserine (KIS)Phospho.ELM 6.0
304Citrulline; in form C8.Swiss-Prot 53.0
Location(AA) Modification Resource
40Phosphoserine(PKB)HMM predict
40Phosphoserine(CAMK2)HMM predict
55N-linkedHMM predict
59Phosphoserine(ATM)HMM predict
62O-linkedHMM predict
112Phosphoserine(CK2)HMM predict
112Phosphoserine(CK1)HMM predict
141Phosphoserine(ATM)HMM predict
141PhosphoserineHMM predict
146Phosphoserine(PKA)HMM predict
169Phosphothreonine(PKA)HMM predict
183MethylarginineHMM predict
190Phosphoserine(PKC)HMM predict
214Phosphothreonine(CK2)HMM predict
232PhosphothreonineHMM predict
232Phosphothreonine(CDK)HMM predict
232Phosphothreonine(MAPK)HMM predict
236Phosphoserine(ATM)HMM predict
244Phosphoserine(PKA)HMM predict
249Phosphoserine(PKA)HMM predict
283Phosphothreonine(PKC)HMM predict
295Phosphoserine(PKA)HMM predict
297Phosphoserine(IKK)HMM predict
299PhosphoserineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001025081
  • Location:chr18 72819777-72858042
  • strand:-
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 72824169 72824590 421 0
CTCF CD4GSE12889 72841372 72841659 287 0
CTCF CD4SISSRdata 72824169 72824590 421 0
CTCF CD4SISSRdata 72841372 72841659 287 0
CTCF G2GSE9613 72824261 72824610 349 0
CTCF G2GSE9613 72847116 72847603 487 0
ER Breast-CancerGSE22609 72839301 72839801 500 0
NRSF JurkatSISSRdata 72857904 72858094 190 0
hScc1 BcellGSE12603 72822197 72823177 980 0
hScc1 BcellGSE12603 72824055 72825970 1915 0
hScc1 BcellGSE12603 72829126 72829386 260 0
hScc1 BcellGSE12603 72841056 72842231 1175 0
hScc1 BcellGSE12603 72847090 72847728 638 0
hScc1 BcellGSE12603 72849348 72850095 747 0
hScc1 CdLSGSE12603 72824055 72824646 591 0
hScc1 CdLSGSE12603 72841056 72841937 881 0
p63 keratinocytesGSE17611 72853434 72854402 968 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
12362 EST chr18 72820788 72821418 351 mRNA MBP chr18 72820710 72857962Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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