Annotation Detail for MDM2
Basic Information Top
| Gene Symbol: | MDM2 ( HDMX,MGC5370,MGC71221,hdm2 ) |
|---|---|
| Gene Full Name: | Mdm2 p53 binding protein homolog (mouse) |
| Band: | 12q15 |
| Quick Links | Entrez ID:4193; OMIM: 164785; Uniprot ID:MDM2_HUMAN; ENSEMBL ID: ENSG00000135679; HGNC ID: 6973 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 166 | Phosphoserine. | |
| 185 | Nuclear localization signal (Potential). | |
| 202 | Nuclear export signal. | |
| 473 | Nucleolar localization signal | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 157 | Phosphoserine | Phospho.ELM 6.0 |
| 166 | Phosphoserine (DAPK3;PKB | |
| 186 | Phosphoserine (PKB | |
| 188 | Phosphoserine (PKB | |
| 240 | Phosphoserine | Phospho.ELM 6.0 |
| 242 | Phosphoserine | Phospho.ELM 6.0 |
| 246 | Phosphoserine | Phospho.ELM 6.0 |
| 260 | Phosphoserine | Phospho.ELM 6.0 |
| 262 | Phosphoserine | Phospho.ELM 6.0 |
| 269 | Phosphoserine | Phospho.ELM 6.0 |
| 394 | Phosphotyrosine (Abl) | Phospho.ELM 6.0 |
| 395 | Phosphoserine (ATM) | Phospho.ELM 6.0 |
| 407 | Phosphoserine (ATR) | Phospho.ELM 6.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 22 | O-linked | HMM predict |
| 48 | Phosphotyrosine(Jak) | HMM predict |
| 116 | Phosphoserine(CK1) | HMM predict |
| 118 | Phosphoserine(CK1) | HMM predict |
| 118 | Phosphoserine(IKK) | HMM predict |
| 148 | Phosphoserine(CK1) | HMM predict |
| 158 | Phosphothreonine(PKC) | HMM predict |
| 159 | Phosphoserine(CDC2) | HMM predict |
| 166 | Phosphoserine(PKB) | HMM predict |
| 166 | Phosphoserine(PKG) | HMM predict |
| 166 | Phosphoserine(CAMK2) | HMM predict |
| 176 | Phosphoserine(CK1) | HMM predict |
| 186 | Phosphoserine(PKB) | HMM predict |
| 188 | Phosphoserine(CK1) | HMM predict |
| 192 | Phosphoserine(CK2) | HMM predict |
| 212 | Phosphoserine(IKK) | HMM predict |
| 212 | Phosphoserine(CK1) | HMM predict |
| 212 | O-linked | HMM predict |
| 213 | O-linked | HMM predict |
| 213 | Phosphoserine(CK1) | HMM predict |
| 213 | O-linked | HMM predict |
| 216 | O-linked | HMM predict |
| 218 | Phosphothreonine(CDC2) | HMM predict |
| 232 | Phosphoserine(CK1) | HMM predict |
| 240 | Phosphoserine(IKK) | HMM predict |
| 240 | Phosphoserine(CK1) | HMM predict |
| 256 | Phosphoserine | HMM predict |
| 259 | Sulfotyrosine | HMM predict |
| 259 | Phosphotyrosine(INSR) | HMM predict |
| 260 | Phosphoserine(CK1) | HMM predict |
| 262 | Phosphoserine(CK1) | HMM predict |
| 269 | Phosphoserine(ATM) | HMM predict |
| 269 | Phosphoserine(CK2) | HMM predict |
| 269 | Phosphoserine(CK2) | HMM predict |
| 276 | Phosphotyrosine(Syk) | HMM predict |
| 290 | Phosphoserine(CK2) | HMM predict |
| 290 | Phosphoserine(IKK) | HMM predict |
| 349 | N-linked | HMM predict |
| 368 | N-linked | HMM predict |
| 388 | Phosphoserine(ATM) | HMM predict |
| 394 | Phosphotyrosine(INSR) | HMM predict |
| 394 | Phosphotyrosine(Syk) | HMM predict |
| 394 | Phosphotyrosine(Abl) | HMM predict |
| 394 | Phosphotyrosine | HMM predict |
| 394 | Sulfotyrosine | HMM predict |
| 395 | Phosphoserine(IKK) | HMM predict |
| 395 | Phosphoserine(ATM) | HMM predict |
| 395 | Phosphoserine(CK1) | HMM predict |
| 399 | O-linked | HMM predict |
| 400 | Phosphoserine(CK1) | HMM predict |
| 406 | Phosphoserine(CK2) | HMM predict |
| 425 | Phosphoserine | HMM predict |
| 425 | Phosphoserine(CK2) | HMM predict |
| 425 | Phosphoserine(CK1) | HMM predict |
| 429 | Phosphoserine(IKK) | HMM predict |
| 464 | S-palmitoyl | HMM predict |
| 475 | S-farnesyl | HMM predict |
| 478 | S-farnesyl | HMM predict |
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq| Micro RNA Name | Stem Loop Name | The chromosome that miRNA located | Publication |
|---|---|---|---|
| hsa-miR-1 | hsa-mir-1-2 | 18 | 19229884 |
| hsa-miR-1 | hsa-mir-1-1 | 20 | 19229884 |
| hsa-miR-125a-3p | hsa-mir-125a | 19 | 20542030 |
| hsa-miR-125a-5p | hsa-mir-125a | 19 | 20542030 |
| hsa-miR-125b | hsa-mir-125b-1 | 11 | 20542030 |
| hsa-miR-125b | hsa-mir-125b-2 | 21 | 20542030 |
| hsa-miR-142-3p | hsa-mir-142 | 17 | 19229884 |
| hsa-miR-191 | hsa-mir-191 | 3 | 21084273 |
| hsa-miR-191* | hsa-mir-191 | 3 | 21084273 |
| hsa-miR-192 | hsa-mir-192 | 11 | 20951946 |
| hsa-miR-192* | hsa-mir-192 | 11 | 20951946 |
| hsa-miR-194 | hsa-mir-194-1 | 1 | 20951946 |
| hsa-miR-215 | hsa-mir-215 | 1 | 20951946 |
| hsa-miR-221 | hsa-mir-221 | X | 20576614 |
| hsa-miR-221* | hsa-mir-221 | X | 20576614 |
| hsa-miR-331-3p | hsa-mir-331 | 12 | 19229884 |
| hsa-miR-331-5p | hsa-mir-331 | 12 | 19229884 |
| hsa-miR-34a | hsa-mir-34a | 1 | 21217645 |
| hsa-miR-34a | hsa-mir-34a | 1 | 20606648 |
| hsa-miR-34a | hsa-mir-34a | 1 | 20581456 |
| hsa-miR-34a | hsa-mir-34a | 1 | 20089965 |
| hsa-miR-34a | hsa-mir-34a | 1 | 18711402 |
| hsa-miR-34a | hsa-mir-34a | 1 | 18677110 |
| hsa-miR-34a | hsa-mir-34a | 1 | 19461653 |
| hsa-miR-34a* | hsa-mir-34a | 1 | 21217645 |
| hsa-miR-34a* | hsa-mir-34a | 1 | 20606648 |
| hsa-miR-34a* | hsa-mir-34a | 1 | 20581456 |
| hsa-miR-34a* | hsa-mir-34a | 1 | 20089965 |
| hsa-miR-34a* | hsa-mir-34a | 1 | 18711402 |
| hsa-miR-34a* | hsa-mir-34a | 1 | 18677110 |
| hsa-miR-34a* | hsa-mir-34a | 1 | 19461653 |
| hsa-miR-34b | hsa-mir-34b | 11 | 20581456 |
| hsa-miR-34b | hsa-mir-34b | 11 | 19461653 |
| hsa-miR-34b* | hsa-mir-34b | 11 | 20581456 |
| hsa-miR-34b* | hsa-mir-34b | 11 | 19461653 |
| hsa-miR-34c-3p | hsa-mir-34c | 11 | 20581456 |
| hsa-miR-34c-3p | hsa-mir-34c | 11 | 19461653 |
| hsa-miR-34c-5p | hsa-mir-34c | 11 | 20581456 |
| hsa-miR-34c-5p | hsa-mir-34c | 11 | 19461653 |
| hsa-miR-605 | hsa-mir-605 | 10 | 21217645 |
| No data |