AutismKB 2.0

Annotation Detail for MGMT


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Basic Information Top
Gene Symbol:MGMT ( - )
Gene Full Name: O-6-methylguanine-DNA methyltransferase
Band: 10q26.3
Quick LinksEntrez ID:4255; OMIM: 156569; Uniprot ID:B4DEE8_HUMAN; ENSEMBL ID: ENSG00000170430; HGNC ID: 7059
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002412
  • Location:chr10 131155455-131455355
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K27me3 colorectalcancer 131150391 131150786 395 4867
PHF8 HeLaGSE20725 131154526 131156038 1512 174
PHF8 Hs68minusFBSGSE20725 131154957 131155818 861 68
PHF8 Hs68plusFBSGSE20725 131154627 131155705 1078 290
Pol2 GM12878GSE19551 131154971 131155325 354 308
RARA MCF7GSE15244 131153875 131154283 408 1377
RARG MCF7GSE15244 131153875 131154179 304 1429
USF2 HepG2E 131150201 131150930 729 4890
hScc1 BcellGSE12603 131154737 131155674 937 250
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 BcellGSE12603 131467517 131467689 172 12248
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 131220525 131222117 1592 0
CBP JurkatGSE17954 131256559 131258390 1831 0
CBP JurkatGSE17954 131268255 131271026 2771 0
CBP T30-glioblastomaGSE21026 131220056 131220587 531 0
ER MCF7GSE19013 131453609 131454027 418 0
FOXA1 MCF7GSE15244 131267509 131268163 654 0
FoxA1 MCF7MACSdata 131267673 131267956 283 0
H3ac HepG2E 131157156 131157497 341 0
KLF4 hESGSE17917 131219796 131220105 309 0
NFkBII GM12878GSE19485 131289385 131290906 1521 0
NRSF JurkatGSE13047 131256891 131257297 406 0
NRSF JurkatSISSRdata 131256906 131257160 254 0
NRSF-mono JurkatQuESTdata 131256917 131257202 285 0
NRSF-mono JurkatQuESTdata 131303462 131303776 314 0
NRSF-poly JurkatQuESTdata 131256888 131257210 322 0
Nanog ESGSE20650 131325207 131325637 430 0
Nanog hESGSE18292 131325070 131325725 655 0
Nanog hESGSE18292 131418998 131419219 221 0
P300 T30-glioblastomaGSE21026 131219811 131220863 1052 0
P300 T30-glioblastomaGSE21026 131233296 131234089 793 0
RARA MCF7GSE15244 131377897 131379462 1565 0
TFAP2C MCF7GSE21234 131210343 131211049 706 0
TFAP2C MCF7GSE21234 131267589 131267974 385 0
TFAP2C MCF7GSE21234 131397979 131398626 647 0
USF1 HepG2E 131210236 131210751 515 0
hScc1 BcellGSE12603 131210133 131210414 281 0
hScc1 BcellGSE12603 131276707 131276862 155 0
hScc1 BcellGSE12603 131339099 131339368 269 0
hScc1 BcellGSE12603 131394089 131394424 335 0
hScc1 BcellGSE12603 131398300 131398608 308 0
hScc1 BcellGSE12603 131407100 131407596 496 0
hScc1 BcellGSE12603 131416866 131417072 206 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
3843 mRNA MGMT chr10 131155455 131455358 2699 mRNA chr10 131196816 131199515 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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