AutismKB 2.0

Annotation Detail for MGP


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Basic Information Top
Gene Symbol:MGP ( MGLAP,NTI )
Gene Full Name: matrix Gla protein
Band: 12p12.3
Quick LinksEntrez ID:4256; OMIM: 154870; Uniprot ID:MGP_HUMAN; ENSEMBL ID: ENSG00000111341; HGNC ID: 7060
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
214-carboxyglutamate (By similarity).
22Phosphoserine.
25Phosphoserine.
28Phosphoserine.
564-carboxyglutamate (By similarity).
604-carboxyglutamate (By similarity).
674-carboxyglutamate (By similarity).
714-carboxyglutamate (By similarity).
Location(AA) Modifications Resource
214-carboxyglutamate (By similarity).Swiss-Prot 53.0
22PhosphoserinePhospho.ELM 6.0
22Phosphoserine.Swiss-Prot 53.0
25Phosphoserine.Swiss-Prot 53.0
25PhosphoserinePhospho.ELM 6.0
28Phosphoserine.Swiss-Prot 53.0
28PhosphoserinePhospho.ELM 6.0
564-carboxyglutamate (By similarity).Swiss-Prot 53.0
604-carboxyglutamate (By similarity).Swiss-Prot 53.0
674-carboxyglutamate (By similarity).Swiss-Prot 53.0
714-carboxyglutamate (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
22PhosphoserineHMM predict
25PhosphoserineHMM predict
28PhosphoserineHMM predict
45Phosphoserine(CDC2)HMM predict
45Phosphoserine(CDK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000900
  • Location:chr12 14926093-14930094
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 14937461 14937668 207 7470
FOXA1 MCF7GSE15244 14929757 14930954 1197 261
GATA3 MCF7GSE15244 14929790 14930918 1128 260
RARA MCF7GSE15244 14930012 14930990 978 407
RARG MCF7GSE15244 14930012 14931121 1109 472
TFAP2C MCF7GSE21234 14930008 14931003 995 411
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 14912698 14913890 1192 12800
p130 SenescentGSE19898 14915760 14916025 265 10201
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 14928897 14929079 182 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018