AutismKB 2.0

Annotation Detail for CIITA


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Basic Information Top
Gene Symbol:CIITA ( C2TA,CIITAIV,MHC2TA,NLRA )
Gene Full Name: class II, major histocompatibility complex, transactivator
Band: 16p13.13
Quick LinksEntrez ID:4261; OMIM: 600005; Uniprot ID:C2TA_HUMAN; ENSEMBL ID: ENSG00000179583; HGNC ID: 7067
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
14Phosphoserine(ATM)HMM predict
20Phosphoserine(IKK)HMM predict
51Phosphotyrosine(Syk)HMM predict
65Phosphotyrosine(INSR)HMM predict
95Phosphotyrosine(INSR)HMM predict
184S-palmitoylHMM predict
264O-linkedHMM predict
270O-linkedHMM predict
280Phosphoserine(CDK)HMM predict
280Phosphoserine(CDC2)HMM predict
286O-linkedHMM predict
288Phosphoserine(CDC2)HMM predict
306Phosphothreonine(PKC)HMM predict
310N-linkedHMM predict
317Phosphoserine(IKK)HMM predict
342Phosphotyrosine(EGFR)HMM predict
374Phosphoserine(CK1)HMM predict
375Phosphoserine(CK1)HMM predict
375Phosphoserine(PKB)HMM predict
377Phosphoserine(CK1)HMM predict
608PhosphoserineHMM predict
610Phosphoserine(IKK)HMM predict
673Phosphoserine(PKG)HMM predict
841Phosphothreonine(MAPK)HMM predict
942Phosphoserine(CK1)HMM predict
944Phosphoserine(CAMK2)HMM predict
1023Phosphoserine(ATM)HMM predict
1026N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000246
  • Location:chr16 10878557-10926339
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 10863743 10864492 749 14440
FOXA1 MCF7GSE15244 10878148 10878844 696 62
Nanog hESGSE18292 10878414 10878576 162 63
Oct1 HelaGSE14283 10873729 10873759 30 4814
Oct1 HelaGSE14283 10876048 10876085 37 2491
P300 T30-glioblastomaGSE21026 10863646 10864554 908 14458
P300 T30-glioblastomaGSE21026 10872140 10873355 1215 5810
RUNX JurkatGSE17954 10860502 10860558 56 18028
STAT1 HeLaGSE12783 10872073 10873511 1438 5766
STAT1 IFNSISSRdata 10872262 10873309 1047 5772
Sox2 hESGSE18292 10878395 10878621 226 50
TAF HelaGSE8489 10863808 10864096 288 14606
hScc1 BcellGSE12603 10870400 10870826 426 7945
hScc1 BcellGSE12603 10873019 10873314 295 5391
p63 keratinocytesGSE17611 10860755 10861703 948 17329
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 10920194 10920522 328 0
CTCF CD4SISSRdata 10920194 10920522 328 0
CTCF HelaGSE12889 10920106 10920492 386 0
CTCF G2GSE9613 10885523 10885729 206 0
CTCF G2GSE9613 10907759 10907978 219 0
CTCF G2GSE9613 10919895 10920513 618 0
Fos K562GSE19551 10884133 10884640 507 0
Myc K562GSE19551 10920136 10920482 346 0
NFkBII GM12878GSE19485 10916655 10918010 1355 0
NRSF JurkatGSE13047 10896032 10897449 1417 0
NRSF JurkatSISSRdata 10896302 10897335 1033 0
NRSF mAbJurkat 10886145 10887610 1465 0
NRSF mAbJurkat 10889943 10890794 851 0
NRSF mAbJurkat 10891264 10891615 351 0
NRSF mAbJurkat 10891948 10893372 1424 0
NRSF mAbJurkat 10896383 10898439 2056 0
NRSF mAbJurkat 10899213 10899495 282 0
NRSF mAbJurkat 10899812 10901128 1316 0
NRSF mAbJurkat 10903229 10904234 1005 0
NRSF-mono JurkatQuESTdata 10896037 10897377 1340 0
NRSF-mono JurkatQuESTdata 10899043 10899331 288 0
NRSF pAbJurkat 10896383 10898439 2056 0
NRSF pAbJurkat 10899213 10899495 282 0
NRSF pAbJurkat 10899812 10900756 944 0
NRSF-poly JurkatQuESTdata 10895914 10897449 1535 0
Oct1 HelaGSE14283 10906972 10907007 35 0
Oct1 HelaGSE14283 10919617 10919652 35 0
RNAII Tamoxifen-MCF7GSE14664 10888659 10888757 98 0
RNAII Tamoxifen-MCF7GSE14664 10888794 10888831 37 0
STAT1 HeLaGSE12782 10879661 10880569 908 0
TFAP2C MCF7GSE21234 10879866 10880484 618 0
hScc1 BcellGSE12603 10878298 10879576 1278 0
hScc1 BcellGSE12603 10903155 10903482 327 0
hScc1 BcellGSE12603 10919792 10920513 721 0
hScc1 CdLSGSE12603 10878048 10879356 1308 0
hScc1 CdLSGSE12603 10919753 10920513 760 0
hScc1 CdLSGSE12603 10921306 10921571 265 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
9617 mRNA MHC2TA chr16 10878539 10933676 155 EST chr16 10878557 10889996Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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