AutismKB 2.0

Annotation Detail for MKI67


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Basic Information Top
Gene Symbol:MKI67 ( KIA )
Gene Full Name: antigen identified by monoclonal antibody Ki-67
Band: 10q26.2
Quick LinksEntrez ID:4288; OMIM: 176741; Uniprot ID:KI67_HUMAN; ENSEMBL ID: ENSG00000148773; HGNC ID: 7107
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
108Phosphoserine.
109Phosphothreonine.
125Phosphoserine.
128Phosphoserine.
131Phosphoserine.
264Phosphoserine.
308Phosphoserine.
328Phosphothreonine.
347Phosphothreonine.
352Phosphoserine.
357Phosphoserine.
374Phosphoserine.
401Phosphothreonine.
411Phosphoserine.
538Phosphoserine.
543Phosphothreonine.
579Phosphoserine.
584Phosphoserine.
630Phosphoserine.
648Phosphoserine.
713Phosphoserine.
761Phosphothreonine.
827Phosphoserine.
859Phosphoserine.
1017Phosphothreonine.
1098Phosphoserine.
1111Phosphothreonine.
1131Phosphoserine.
1139Phosphothreonine.
1176Phosphothreonine.
1193Phosphothreonine.
1207Phosphoserine.
1233Phosphothreonine.
1237Phosphothreonine.
1253Phosphoserine.
1256Phosphoserine.
1261Phosphothreonine.
1298Phosphothreonine.
1302Phosphoserine.
1315Phosphothreonine.
1327Phosphothreonine.
1329Phosphoserine.
1335Phosphothreonine.
1355Phosphothreonine.
1375Phosphoserine.
1376Phosphoserine.
1383Phosphothreonine.
1503Phosphothreonine.
1506Phosphoserine.
1540Phosphothreonine.
1546Phosphoserine.
1552Phosphotyrosine.
1557Phosphothreonine.
1565Phosphothreonine.
1569Phosphothreonine.
1571Phosphoserine.
1618Phosphoserine.
1628Phosphoserine.
1629Phosphoserine.
1636Phosphoserine.
1639N6-acetyllysine.
1679Phosphoserine.
1689Phosphoserine.
1719Phosphothreonine.
1721Phosphoserine.
1726Phosphoserine.
1740Phosphoserine.
1747Phosphothreonine.
1764Phosphothreonine.
1784Phosphothreonine.
1801Phosphothreonine.
1815Phosphoserine.
1841Phosphothreonine.
1861Phosphoserine.
1864Phosphoserine.
1869Phosphothreonine.
1897Phosphothreonine.
1923Phosphothreonine.
1937Phosphoserine.
1983Phosphoserine.
2002Phosphoserine.
2005N6-acetyllysine.
2065Phosphothreonine.
2072Phosphoserine.
2085Phosphothreonine.
2105Phosphoserine.
2113Phosphothreonine.
2135Phosphoserine.
2203Phosphothreonine.
2211Phosphothreonine.
2223Phosphoserine.
2231Phosphothreonine.
2239Phosphoserine.
2264N6-acetyllysine.
2285Phosphothreonine.
2299Phosphoserine.
2305Phosphothreonine.
2325Phosphothreonine.
2328Phosphothreonine.
2332Phosphothreonine.
2344Phosphoserine.
2352Phosphothreonine.
2355Phosphoserine.
2389Phosphothreonine.
2395Phosphoserine.
2406Phosphothreonine.
2420Phosphoserine.
2426Phosphothreonine.
2446Phosphothreonine.
2466Phosphoserine.
2471Phosphoserine.
2505Phosphoserine.
2508Phosphothreonine.
2509Phosphothreonine.
2528Phosphoserine.
2588Phosphoserine.
2638Phosphoserine.
2708Phosphoserine.
2827Phosphoserine.
2828Phosphoserine.
3041Phosphoserine.
3042Phosphoserine.
3082Phosphoserine.
3207Phosphoserine.
3213Phosphothreonine.
3216Phosphoserine.
3223Phosphothreonine.
Location(AA) Modifications Resource
108Phosphoserine.Swiss-Prot 53.0
108PhosphoserinePhospho.ELM 6.0
308Phosphoserine.Swiss-Prot 53.0
308PhosphoserinePhospho.ELM 6.0
328Phosphothreonine.Swiss-Prot 53.0
357Phosphoserine.Swiss-Prot 53.0
357PhosphoserinePhospho.ELM 6.0
374Phosphoserine.Swiss-Prot 53.0
374PhosphoserinePhospho.ELM 6.0
543PhosphothreoninePhospho.ELM 6.0
543Phosphothreonine.Swiss-Prot 53.0
579PhosphoserinePhospho.ELM 6.0
579Phosphoserine.Swiss-Prot 53.0
584Phosphoserine.Swiss-Prot 53.0
584PhosphoserinePhospho.ELM 6.0
648Phosphoserine.Swiss-Prot 53.0
648PhosphoserinePhospho.ELM 6.0
827PhosphoserinePhospho.ELM 6.0
1098PhosphoserinePhospho.ELM 6.0
1098Phosphoserine.Swiss-Prot 53.0
1131PhosphoserinePhospho.ELM 6.0
1131Phosphoserine.Swiss-Prot 53.0
1139PhosphothreoninePhospho.ELM 6.0
1193PhosphothreoninePhospho.ELM 6.0
1193Phosphothreonine.Swiss-Prot 53.0
1253PhosphoserinePhospho.ELM 6.0
1253Phosphoserine.Swiss-Prot 53.0
1256PhosphoserinePhospho.ELM 6.0
1261PhosphothreoninePhospho.ELM 6.0
1327PhosphothreoninePhospho.ELM 6.0
1327Phosphothreonine.Swiss-Prot 53.0
1335Phosphothreonine.Swiss-Prot 53.0
1335PhosphothreoninePhospho.ELM 6.0
1375Phosphoserine.Swiss-Prot 53.0
1375PhosphoserinePhospho.ELM 6.0
1376Phosphoserine.Swiss-Prot 53.0
1376PhosphoserinePhospho.ELM 6.0
1557PhosphothreoninePhospho.ELM 6.0
1557Phosphothreonine.Swiss-Prot 53.0
1569Phosphothreonine.Swiss-Prot 53.0
1740PhosphoserinePhospho.ELM 6.0
1740Phosphoserine.Swiss-Prot 53.0
1747PhosphothreoninePhospho.ELM 6.0
1801Phosphothreonine.Swiss-Prot 53.0
1801PhosphothreoninePhospho.ELM 6.0
1815PhosphoserinePhospho.ELM 6.0
1815Phosphoserine.Swiss-Prot 53.0
1861PhosphoserinePhospho.ELM 6.0
1861Phosphoserine.Swiss-Prot 53.0
1869PhosphothreoninePhospho.ELM 6.0
1923PhosphothreoninePhospho.ELM 6.0
1923Phosphothreonine.Swiss-Prot 53.0
2002Phosphoserine.Swiss-Prot 53.0
2002PhosphoserinePhospho.ELM 6.0
2085Phosphothreonine.Swiss-Prot 53.0
2085PhosphothreoninePhospho.ELM 6.0
2105PhosphoserinePhospho.ELM 6.0
2105Phosphoserine.Swiss-Prot 53.0
2223PhosphoserinePhospho.ELM 6.0
2223Phosphoserine.Swiss-Prot 53.0
2231PhosphothreoninePhospho.ELM 6.0
2406PhosphothreoninePhospho.ELM 6.0
2406Phosphothreonine.Swiss-Prot 53.0
2528Phosphoserine.Swiss-Prot 53.0
2528PhosphoserinePhospho.ELM 6.0
2638PhosphoserinePhospho.ELM 6.0
2708PhosphoserinePhospho.ELM 6.0
2708Phosphoserine.Swiss-Prot 53.0
2827Phosphoserine.Swiss-Prot 53.0
2828PhosphoserinePhospho.ELM 6.0
2828Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
9Phosphothreonine(PKC)HMM predict
62N-linkedHMM predict
67N-linkedHMM predict
72N-linkedHMM predict
99N-linkedHMM predict
104N-linkedHMM predict
125Phosphoserine(PKA)HMM predict
125Phosphoserine(PKG)HMM predict
131Phosphoserine(CK2)HMM predict
143Phosphotyrosine(INSR)HMM predict
152Phosphoserine(PKG)HMM predict
166Phosphoserine(CK2)HMM predict
233N-linkedHMM predict
270Phosphotyrosine(Syk)HMM predict
296Phosphoserine(IKK)HMM predict
308Phosphoserine(MAPK)HMM predict
328Phosphothreonine(CDK)HMM predict
351Phosphotyrosine(Abl)HMM predict
352Phosphoserine(IKK)HMM predict
357Phosphoserine(CDC2)HMM predict
367Phosphotyrosine(Jak)HMM predict
374Phosphoserine(PKG)HMM predict
391Phosphothreonine(MAPK)HMM predict
391Phosphothreonine(CDK)HMM predict
396Phosphoserine(PKG)HMM predict
399N-linkedHMM predict
420Phosphoserine(CK1)HMM predict
462Phosphoserine(CK1)HMM predict
476Phosphoserine(ATM)HMM predict
507Phosphoserine(PKG)HMM predict
507Phosphoserine(CAMK2)HMM predict
525Phosphothreonine(MAPK)HMM predict
534Phosphothreonine(PKC)HMM predict
563Phosphoserine(CK2)HMM predict
565Phosphoserine(CK1)HMM predict
579Phosphoserine(CDC2)HMM predict
579Phosphoserine(MAPK)HMM predict
584Phosphoserine(CDC2)HMM predict
584PhosphoserineHMM predict
598Phosphoserine(PKA)HMM predict
598Phosphoserine(PKC)HMM predict
598Phosphoserine(PKG)HMM predict
605Phosphoserine(CDK)HMM predict
606Phosphoserine(CK1)HMM predict
607O-linkedHMM predict
607Phosphoserine(IKK)HMM predict
609Phosphoserine(CK1)HMM predict
609Phosphoserine(IKK)HMM predict
609PhosphoserineHMM predict
611Phosphothreonine(PKC)HMM predict
634Phosphoserine(ATM)HMM predict
648Phosphoserine(PKA)HMM predict
648Phosphoserine(CK2)HMM predict
672Phosphothreonine(PKC)HMM predict
704Phosphoserine(ATM)HMM predict
753Phosphoserine(CK2)HMM predict
761Phosphothreonine(CDC2)HMM predict
793Phosphoserine(CK2)HMM predict
793Phosphoserine(ATM)HMM predict
844Phosphothreonine(CDC2)HMM predict
844Phosphothreonine(MAPK)HMM predict
849Phosphotyrosine(Syk)HMM predict
859Phosphoserine(CK2)HMM predict
866O-linkedHMM predict
866O-linkedHMM predict
866Phosphoserine(CK1)HMM predict
870O-linkedHMM predict
873N-linkedHMM predict
893Phosphoserine(CK1)HMM predict
997Phosphoserine(PKC)HMM predict
1017Phosphothreonine(MAPK)HMM predict
1019Phosphothreonine(MAPK)HMM predict
1048O-linkedHMM predict
1083Phosphothreonine(PKC)HMM predict
1091Phosphothreonine(CDC2)HMM predict
1091Phosphothreonine(MAPK)HMM predict
1091Phosphothreonine(CDK)HMM predict
1098Phosphoserine(CK1)HMM predict
1111Phosphothreonine(MAPK)HMM predict
1139Phosphothreonine(MAPK)HMM predict
1167Phosphothreonine(PKA)HMM predict
1176Phosphothreonine(MAPK)HMM predict
1213Phosphothreonine(MAPK)HMM predict
1233Phosphothreonine(MAPK)HMM predict
1246Phosphothreonine(PKC)HMM predict
1256Phosphoserine(ATM)HMM predict
1261Phosphothreonine(MAPK)HMM predict
1261Phosphothreonine(CDK)HMM predict
1298Phosphothreonine(MAPK)HMM predict
1325N-linkedHMM predict
1335Phosphothreonine(MAPK)HMM predict
1335PhosphothreonineHMM predict
1355Phosphothreonine(MAPK)HMM predict
1383O-linkedHMM predict
1383Phosphothreonine(MAPK)HMM predict
1385Phosphothreonine(MAPK)HMM predict
1393Phosphothreonine(MAPK)HMM predict
1414O-linkedHMM predict
1485Phosphothreonine(CDK)HMM predict
1496Phosphoserine(IKK)HMM predict
1503Phosphothreonine(MAPK)HMM predict
1503Phosphothreonine(CDK)HMM predict
1506O-linkedHMM predict
1531Phosphothreonine(PKA)HMM predict
1533Phosphoserine(PKC)HMM predict
1540Phosphothreonine(MAPK)HMM predict
1552Phosphotyrosine(INSR)HMM predict
1567N-linkedHMM predict
1577Phosphothreonine(PKC)HMM predict
1577Phosphothreonine(MAPK)HMM predict
1618Phosphoserine(ATM)HMM predict
1656O-linkedHMM predict
1656O-linkedHMM predict
1689Phosphoserine(CK1)HMM predict
1719Phosphothreonine(MAPK)HMM predict
1721Phosphoserine(MAPK)HMM predict
1740Phosphoserine(ATM)HMM predict
1747Phosphothreonine(MAPK)HMM predict
1747Phosphothreonine(CDK)HMM predict
1750O-linkedHMM predict
1775Phosphothreonine(PKA)HMM predict
1784Phosphothreonine(MAPK)HMM predict
1821Phosphothreonine(PKC)HMM predict
1846N-linkedHMM predict
1854Phosphothreonine(PKC)HMM predict
1864Phosphoserine(ATM)HMM predict
1869O-linkedHMM predict
1869Phosphothreonine(CDC2)HMM predict
1869Phosphothreonine(MAPK)HMM predict
1871Phosphothreonine(MAPK)HMM predict
1880Phosphoserine(PKG)HMM predict
1897Phosphothreonine(PKA)HMM predict
1937Phosphoserine(CDK)HMM predict
1943Phosphothreonine(PKC)HMM predict
1943Phosphothreonine(MAPK)HMM predict
1943PhosphothreonineHMM predict
1963Phosphothreonine(MAPK)HMM predict
1983Phosphoserine(CDC2)HMM predict
1991O-linkedHMM predict
1991Phosphothreonine(MAPK)HMM predict
1991Phosphothreonine(CDK)HMM predict
2022O-linkedHMM predict
2065Phosphothreonine(CDC2)HMM predict
2065Phosphothreonine(MAPK)HMM predict
2065Phosphothreonine(CDK)HMM predict
2072Phosphoserine(CK1)HMM predict
2085Phosphothreonine(MAPK)HMM predict
2113O-linkedHMM predict
2113Phosphothreonine(MAPK)HMM predict
2117Phosphothreonine(PKC)HMM predict
2183Phosphothreonine(CDC2)HMM predict
2183Phosphothreonine(MAPK)HMM predict
2212Phosphothreonine(CDK)HMM predict
2259Phosphothreonine(PKA)HMM predict
2261Phosphoserine(PKC)HMM predict
2268Phosphothreonine(MAPK)HMM predict
2305Phosphothreonine(CDC2)HMM predict
2305Phosphothreonine(MAPK)HMM predict
2305Phosphothreonine(CDK)HMM predict
2352O-linkedHMM predict
2352Phosphothreonine(MAPK)HMM predict
2352Phosphothreonine(CDK)HMM predict
2356Phosphothreonine(PKC)HMM predict
2380Phosphothreonine(PKA)HMM predict
2382Phosphoserine(PKC)HMM predict
2389Phosphothreonine(MAPK)HMM predict
2426Phosphothreonine(CDC2)HMM predict
2426Phosphothreonine(MAPK)HMM predict
2446Phosphothreonine(MAPK)HMM predict
2466Phosphoserine(CDC2)HMM predict
2471Phosphoserine(IKK)HMM predict
2474Phosphothreonine(PKC)HMM predict
2505O-linkedHMM predict
2540Phosphothreonine(PKC)HMM predict
2548Phosphothreonine(PKC)HMM predict
2588Phosphoserine(CDK)HMM predict
2594O-linkedHMM predict
2594O-linkedHMM predict
2599Phosphoserine(PKC)HMM predict
2600Phosphothreonine(PKC)HMM predict
2626O-linkedHMM predict
2626O-linkedHMM predict
2689Phosphoserine(CK1)HMM predict
2689Phosphoserine(CK2)HMM predict
2720Phosphothreonine(PKC)HMM predict
2773Phosphothreonine(MAPK)HMM predict
2781Phosphothreonine(PKC)HMM predict
2783Phosphoserine(PKC)HMM predict
2828Phosphoserine(CDC2)HMM predict
2837Phosphoserine(PKC)HMM predict
2837Phosphoserine(CDC2)HMM predict
2838Phosphoserine(PKC)HMM predict
2865O-linkedHMM predict
2865O-linkedHMM predict
2882Phosphothreonine(PKC)HMM predict
2925Phosphoserine(ATM)HMM predict
2927Phosphothreonine(MAPK)HMM predict
2941O-linkedHMM predict
2949O-linkedHMM predict
2949O-linkedHMM predict
2949Phosphothreonine(MAPK)HMM predict
2987Phosphoserine(IKK)HMM predict
2988N-linkedHMM predict
2989O-linkedHMM predict
2990Phosphoserine(PKA)HMM predict
3005Phosphoserine(IKK)HMM predict
3051Phosphoserine(PKG)HMM predict
3082Phosphoserine(IKK)HMM predict
3097N-linkedHMM predict
3142MethyllysineHMM predict
3162N-linkedHMM predict
3165Phosphoserine(CK1)HMM predict
3165Phosphoserine(ATM)HMM predict
3213Phosphothreonine(PKC)HMM predict
3213Phosphothreonine(CDK)HMM predict
3223Phosphothreonine(PKA)HMM predict
3247Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002417
  • Location:chr10 129784913-129814644
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
E2F4 G0GSE7516 129814369 129815009 640 45
Fos K562GSE19551 129814447 129814888 441 23
Oct4 hESGSE17917 129814527 129814921 394 80
p130 QuiescentGSE19898 129814615 129814858 243 92
p130 SenescentGSE19898 129814469 129815077 608 129
p130 shRbQuiescentGSE19898 129814563 129815157 594 216
p130 shRbSenescentGSE19898 129814532 129815034 502 139
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Rb GrowingGSE19898 129780095 129780298 203 4717
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me2 HCT116GSE10453 129813197 129813625 428 0
H3ac HepG2E 129812381 129814080 1699 0
LIN9 G0GSE7516 129813197 129815009 1812 0
LIN9 SGSE7516 129813545 129815009 1464 0
NRSF JurkatGSE13047 129801039 129801715 676 0
NRSF mAbJurkat 129800766 129802686 1920 0
NRSF-mono JurkatQuESTdata 129801173 129801670 497 0
hScc1 BcellGSE12603 129814080 129814723 643 0
p130 G0GSE7516 129813545 129815009 1464 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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