AutismKB 2.0

Annotation Detail for ACHE


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Basic Information Top
Gene Symbol:ACHE ( ARACHE,N-ACHE,YT )
Gene Full Name: acetylcholinesterase
Band: 7q22.1
Quick LinksEntrez ID:43; OMIM: 100740; Uniprot ID:ACES_HUMAN; ENSEMBL ID: ENSG00000087085; HGNC ID: 108
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
296N-linked (GlcNAc...) (Potential).
381N-linked (GlcNAc...).
495N-linked (GlcNAc...).
Location(AA) Modifications Resource
164PhosphotyrosinePhospho.ELM 6.0
296N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
381N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
495N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
15Phosphoserine(MAPK)HMM predict
140O-linkedHMM predict
141Phosphoserine(CDC2)HMM predict
141Phosphoserine(IKK)HMM predict
141Phosphoserine(MAPK)HMM predict
141O-linkedHMM predict
143Phosphothreonine(CDK)HMM predict
280Phosphothreonine(PKA)HMM predict
296N-linkedHMM predict
381N-linkedHMM predict
466Phosphoserine(PKA)HMM predict
467Phosphothreonine(PKC)HMM predict
495N-linkedHMM predict
576Phosphothreonine(CK2)HMM predict
611CysteineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000665
  • Location:chr7 100325551-100331476
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 100338278 100338561 283 6943
Gata2 K562GSE18868 100332694 100334038 1344 1890
Oct1 H2O2-HelaGSE14283 100332799 100332832 33 1339
Oct1 HelaGSE14283 100332799 100332832 33 1339
hScc1 BcellGSE12603 100332466 100333191 725 1352
hScc1 CdLSGSE12603 100331816 100333388 1572 1126
hScc1 G2GSE9613 100329406 100333633 4227 43
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 100329523 100333412 3889 0
NFkBII GM12892GSE19485 100330166 100331394 1228 0
Oct1 HelaGSE14283 100329764 100329809 45 0
STAT1 IFNSISSRdata 100329702 100330335 633 0
hScc1 BcellGSE12603 100330040 100330934 894 0
hScc1 CdLSGSE12603 100330180 100330767 587 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018