AutismKB 2.0

Annotation Detail for NR3C2


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Basic Information Top
Gene Symbol:NR3C2 ( FLJ41052,MCR,MGC133092,MLR,MR,NR3C2VIT )
Gene Full Name: nuclear receptor subfamily 3, group C, member 2
Band: 4q31
Quick LinksEntrez ID:4306; OMIM: 600983; Uniprot ID:MCR_HUMAN; ENSEMBL ID: ENSG00000151623; HGNC ID: 7979
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
42Phosphotyrosine(INSR)HMM predict
42Phosphotyrosine(EGFR)HMM predict
42Phosphotyrosine(Syk)HMM predict
42Phosphotyrosine(SRC)HMM predict
47N-linkedHMM predict
57N-linkedHMM predict
58N-linkedHMM predict
117SulfotyrosineHMM predict
119SulfotyrosineHMM predict
129Phosphoserine(CDC2)HMM predict
153Phosphothreonine(PKC)HMM predict
155Phosphoserine(IKK)HMM predict
159Phosphothreonine(CDK)HMM predict
159Phosphothreonine(MAPK)HMM predict
170Phosphoserine(CK1)HMM predict
193Phosphoserine(IKK)HMM predict
193Phosphoserine(CK2)HMM predict
199N-linkedHMM predict
202O-linkedHMM predict
206Phosphoserine(CDC2)HMM predict
215O-linkedHMM predict
216O-linkedHMM predict
219Phosphoserine(PKA)HMM predict
222O-linkedHMM predict
233O-linkedHMM predict
238Phosphoserine(MAPK)HMM predict
246O-linkedHMM predict
250PhosphoserineHMM predict
250Phosphoserine(IKK)HMM predict
259Phosphoserine(CDC2)HMM predict
263Phosphoserine(CDC2)HMM predict
271Phosphoserine(PKG)HMM predict
273O-linkedHMM predict
274Phosphoserine(ATM)HMM predict
277Phosphoserine(IKK)HMM predict
287Phosphoserine(CDC2)HMM predict
290N-linkedHMM predict
298Phosphoserine(IKK)HMM predict
299Phosphoserine(CDC2)HMM predict
304N-linkedHMM predict
305N-linkedHMM predict
309O-linkedHMM predict
318N-linkedHMM predict
324PhosphoserineHMM predict
324Phosphoserine(CDK)HMM predict
324Phosphoserine(MAPK)HMM predict
324Phosphoserine(CDC2)HMM predict
329Phosphothreonine(PKC)HMM predict
332Phosphoserine(PKA)HMM predict
332O-linkedHMM predict
332Phosphoserine(IKK)HMM predict
344O-linkedHMM predict
346O-linkedHMM predict
348O-linkedHMM predict
349O-linkedHMM predict
354Phosphothreonine(PKC)HMM predict
361Phosphoserine(CDC2)HMM predict
361Phosphoserine(CDK)HMM predict
424Phosphoserine(ATM)HMM predict
435Phosphoserine(IKK)HMM predict
435Phosphoserine(PKA)HMM predict
444N-linkedHMM predict
448N-linkedHMM predict
457SulfotyrosineHMM predict
466Phosphotyrosine(Syk)HMM predict
466Phosphotyrosine(INSR)HMM predict
502Phosphotyrosine(Jak)HMM predict
503Phosphotyrosine(EGFR)HMM predict
583N-linkedHMM predict
588Phosphothreonine(PKC)HMM predict
593O-linkedHMM predict
637Phosphotyrosine(INSR)HMM predict
710Phosphotyrosine(INSR)HMM predict
731O-linkedHMM predict
735Phosphothreonine(MAPK)HMM predict
869Phosphotyrosine(INSR)HMM predict
912N-linkedHMM predict
913N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000901
  • Location:chr4 149219369-149582972
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 149584732 149586547 1815 2667
Fos K562GSE19551 149582870 149583505 635 215
Oct1 HelaGSE14283 149586171 149586205 34 3216
P300 T30-glioblastomaGSE21026 149583037 149583658 621 375
USF1 HepG2E 149582932 149583620 688 304
hScc1 BcellGSE12603 149584200 149586019 1819 2137
hScc1 G2GSE9613 149584732 149585985 1253 2386
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 149220611 149220851 240 0
CTCF G2GSE9613 149230946 149231123 177 0
CTCF G2GSE9613 149231653 149232072 419 0
CTCF G2GSE9613 149249059 149249256 197 0
CTCF G2GSE9613 149257948 149258095 147 0
CTCF G2GSE9613 149342274 149342481 207 0
CTCF G2GSE9613 149379526 149379778 252 0
CTCF G2GSE9613 149414364 149414544 180 0
CTCF G2GSE9613 149482403 149482982 579 0
CTCF G2GSE9613 149526291 149526525 234 0
CTCF G2GSE9613 149569276 149569606 330 0
CTCF G2GSE9613 149582530 149583099 569 0
ER Fulvestrant-MCF7GSE14664 149391899 149391934 35 0
ER Fulvestrant-MCF7GSE14664 149567909 149567944 35 0
H3K4me3 colorectalcancer 149581012 149582616 1604 0
NRSF JurkatGSE13047 149347540 149348205 665 0
NRSF JurkatSISSRdata 149347613 149348067 454 0
NRSF mAbJurkat 149344916 149347441 2525 0
NRSF-mono JurkatQuESTdata 149347539 149348058 519 0
NRSF-poly JurkatQuESTdata 149347677 149348333 656 0
Nanog ESGSE20650 149464012 149464314 302 0
Nanog hESGSE18292 149344161 149344538 377 0
Oct1 H2O2-HelaGSE14283 149375832 149375859 27 0
Oct1 H2O2-HelaGSE14283 149392665 149392695 30 0
Oct1 H2O2-HelaGSE14283 149415648 149415687 39 0
Oct1 HelaGSE14283 149282377 149282404 27 0
Oct1 HelaGSE14283 149286134 149286208 74 0
Oct1 HelaGSE14283 149288351 149288383 32 0
Oct1 HelaGSE14283 149348789 149348866 77 0
Oct1 HelaGSE14283 149375831 149375860 29 0
Oct1 HelaGSE14283 149392665 149392694 29 0
Oct1 HelaGSE14283 149436259 149436327 68 0
Oct1 HelaGSE14283 149456835 149456863 28 0
Oct1 HelaGSE14283 149477396 149477468 72 0
Oct1 HelaGSE14283 149554435 149554486 51 0
P300 T0-glioblastomaGSE21026 149516416 149517180 764 0
TFAP2C MCF7GSE21234 149582570 149583338 768 0
USF1 HepG2E 149581845 149582654 809 0
hScc1 BcellGSE12603 149231765 149232141 376 0
hScc1 BcellGSE12603 149582569 149583099 530 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-124 hsa-mir-124-1 8 19944075
hsa-miR-124 hsa-mir-124-2 8 19944075
hsa-miR-124 hsa-mir-124-3 20 19944075
hsa-miR-124* hsa-mir-124-1 8 19944075
hsa-miR-130a hsa-mir-130a 11 19944075
hsa-miR-130a* hsa-mir-130a 11 19944075
hsa-miR-135a hsa-mir-135a-1 3 19944075
hsa-miR-135a hsa-mir-135a-2 12 19944075
hsa-miR-135a* hsa-mir-135a-1 3 19944075
hsa-miR-19b hsa-mir-19b-1 13 19944075
hsa-miR-19b hsa-mir-19b-2 X 19944075
hsa-miR-30e hsa-mir-30e 1 19944075
hsa-miR-30e* hsa-mir-30e 1 19944075
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
20311 EST chr4 149425226 149487625 62399 mRNA NR3C2 chr4 149357524 149721128 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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