AutismKB 2.0

Annotation Detail for MME


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Basic Information Top
Gene Symbol:MME ( CALLA,CD10,DKFZp686O16152,MGC126681,MGC126707,NEP )
Gene Full Name: membrane metallo-endopeptidase
Band: 3q25.2
Quick LinksEntrez ID:4311; OMIM: 120520; Uniprot ID:NEP_HUMAN; ENSEMBL ID: ENSG00000196549; HGNC ID: 7154
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
23Stop-transfer sequence (Potential).
145N-linked (GlcNAc...).
285N-linked (GlcNAc...).
325N-linked (GlcNAc...).
628N-linked (GlcNAc...).
Location(AA) Modifications Resource
145N-linked (GlcNAc...).Swiss-Prot 53.0
285N-linked (GlcNAc...).Swiss-Prot 53.0
325N-linked (GlcNAc...).Swiss-Prot 53.0
628N-linked (GlcNAc...).Swiss-Prot 53.0
Location(AA) Modification Resource
6Phosphoserine(ATM)HMM predict
15Phosphothreonine(MAPK)HMM predict
145N-linkedHMM predict
232Phosphotyrosine(Syk)HMM predict
285N-linkedHMM predict
313Phosphoserine(CK1)HMM predict
325N-linkedHMM predict
328N-linkedHMM predict
382Phosphoserine(CK1)HMM predict
502SulfotyrosineHMM predict
507Phosphotyrosine(INSR)HMM predict
548Phosphoserine(CDK)HMM predict
570Phosphoserine(IKK)HMM predict
575Phosphotyrosine(INSR)HMM predict
702Phosphotyrosine(INSR)HMM predict
739Phosphoserine(PKG)HMM predict
740Phosphotyrosine(INSR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000902
  • Location:chr3 156280129-156384211
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K27me3 colorectalcancer 156278878 156280047 1169 667
H3K4me3 colorectalcancer 156279564 156279961 397 367
Myc K562GSE19551 156266148 156266347 199 13882
Myc K562GSE19551 156271594 156271982 388 8342
Oct4 hESGSE17917 156279977 156280168 191 57
SRF GMOGSE8489 156265644 156265916 272 14350
No data
No data
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-155 hsa-mir-155 21 20947507
hsa-miR-155* hsa-mir-155 21 20947507
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
18881 mRNA MME chr3 156280160 156384194 198 EST chr3 156359238 156383760Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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