AutismKB 2.0

Annotation Detail for MMP8


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MMP8 ( CLG1,HNC,MMP-8,PMNL-CL )
Gene Full Name: matrix metallopeptidase 8 (neutrophil collagenase)
Band: 11q22.2
Quick LinksEntrez ID:4317; OMIM: 120355; Uniprot ID:MMP8_HUMAN; ENSEMBL ID: ENSG00000118113; HGNC ID: 7175
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
54N-linked (GlcNAc...) (Probable).
73N-linked (GlcNAc...) (Probable).
96Cysteine switch (By similarity).
112N-linked (GlcNAc...).
204N-linked (GlcNAc...) (Potential).
246N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
54N-linked (GlcNAc...) (Probable).Swiss-Prot 53.0
73N-linked (GlcNAc...) (Probable).Swiss-Prot 53.0
112N-linked (GlcNAc...).Swiss-Prot 53.0
204N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
246N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
48Phosphotyrosine(Syk)HMM predict
48Phosphotyrosine(SRC)HMM predict
54N-linkedHMM predict
57N-linkedHMM predict
73N-linkedHMM predict
79N-linkedHMM predict
112N-linkedHMM predict
119N-linkedHMM predict
141Phosphoserine(IKK)HMM predict
152Phosphoserine(PKG)HMM predict
246N-linkedHMM predict
247Phosphotyrosine(INSR)HMM predict
271O-linkedHMM predict
275O-linkedHMM predict
275Phosphothreonine(MAPK)HMM predict
453Phosphothreonine(PKA)HMM predict
463AsparagineHMM predict
465ArginineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002424
  • Location:chr11 102088541-102100867
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 102105578 102105639 61 4741
ER E2-MCF7GSE14664 102105842 102105874 32 4991
ER Fulvestrant-MCF7GSE14664 102111462 102111538 76 10633
Oct1 H2O2-HelaGSE14283 102118062 102118100 38 17214
Oct1 HelaGSE14283 102118062 102118100 38 17214
TAFII hESGSE17917 102109130 102109513 383 8454
hScc1 CdLSGSE12603 102109104 102109697 593 8533
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 102086641 102086677 36 1883
Oct1 HelaGSE14283 102086641 102086678 37 1882
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER Fulvestrant-MCF7GSE14664 102096490 102096523 33 0
ER Fulvestrant-MCF7GSE14664 102097256 102097290 34 0
Oct1 H2O2-HelaGSE14283 102097260 102097290 30 0
Oct1 H2O2-HelaGSE14283 102098327 102098363 36 0
Oct1 HelaGSE14283 102089861 102089891 30 0
Oct1 HelaGSE14283 102094512 102094541 29 0
Oct1 HelaGSE14283 102097260 102097290 30 0
Oct1 HelaGSE14283 102098327 102098364 37 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7a hsa-let-7a-1 9 21292542
hsa-let-7a hsa-let-7a-2 11 21292542
hsa-let-7a hsa-let-7a-3 22 21292542
hsa-let-7a* hsa-let-7a-1 9 21292542
hsa-let-7a* hsa-let-7a-3 22 21292542
hsa-let-7b hsa-let-7b 22 21292542
hsa-let-7b* hsa-let-7b 22 21292542
hsa-let-7c hsa-let-7c 21 21292542
hsa-let-7c* hsa-let-7c 21 21292542
hsa-let-7d hsa-let-7d 9 21292542
hsa-let-7d* hsa-let-7d 9 21292542
hsa-let-7e hsa-let-7e 19 21292542
hsa-let-7e* hsa-let-7e 19 21292542
hsa-let-7f hsa-let-7f-1 9 21292542
hsa-let-7f hsa-let-7f-2 X 21292542
hsa-let-7f-1* hsa-let-7f-1 9 21292542
hsa-let-7f-2* hsa-let-7f-2 X 21292542
hsa-let-7g hsa-let-7g 3 21292542
hsa-let-7g* hsa-let-7g 3 21292542
hsa-let-7i hsa-let-7i 12 21292542
hsa-let-7i* hsa-let-7i 12 21292542
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved