AutismKB 2.0

Annotation Detail for MMP9


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Basic Information Top
Gene Symbol:MMP9 ( CLG4B,GELB,MANDP2,MMP-9 )
Gene Full Name: matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
Band: 20q13.12
Quick LinksEntrez ID:4318; OMIM: 120361; Uniprot ID:MMP9_HUMAN; ENSEMBL ID: ENSG00000100985; HGNC ID: 7176
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
38N-linked (GlcNAc...) (Potential).
104Cysteine switch (By similarity).
120N-linked (GlcNAc...) (Potential).
127N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
38N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
120N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
127N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
16S-palmitoylHMM predict
17S-palmitoylHMM predict
38N-linkedHMM predict
120N-linkedHMM predict
152Phosphothreonine(MAPK)HMM predict
242Phosphoserine(IKK)HMM predict
300Phosphoserine(IKK)HMM predict
359Phosphoserine(IKK)HMM predict
456O-linkedHMM predict
456O-linkedHMM predict
457O-linkedHMM predict
466O-linkedHMM predict
466O-linkedHMM predict
478O-linkedHMM predict
490O-linkedHMM predict
498O-linkedHMM predict
502O-linkedHMM predict
503O-linkedHMM predict
505O-linkedHMM predict
505O-linkedHMM predict
506O-linkedHMM predict
648Phosphoserine(PKB)HMM predict
672Phosphotyrosine(Jak)HMM predict
686Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004994
  • Location:chr20 44070953-44078605
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 44057104 44057908 804 13448
FOXA1 eGFPGSE10845 44057104 44057908 804 13448
NFkBII GM10847GSE19485 44069701 44071105 1404 551
NFkBII GM12878GSE19485 44069636 44071364 1728 454
NFkBII GM12892GSE19485 44069941 44071316 1375 325
NFkBII GM15510GSE19485 44069785 44070979 1194 572
NFkBII GM18505GSE19485 44069697 44070915 1218 648
P300 T30-glioblastomaGSE21026 44055465 44056195 730 15124
RARA MCF7GSE15244 44057104 44057908 804 13448
TFAP2C MCF7GSE21234 44055282 44056198 916 15214
TFAP2C MCF7GSE21234 44056824 44058125 1301 13479
TFAP2C MCF7GSE21234 44066633 44067227 594 4024
hScc1 BcellGSE12603 44070267 44070443 176 599
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 44084769 44084963 194 6261
PHF8 293TGSE20725 44083510 44084187 677 5243
TFAP2C MCF7GSE21234 44083983 44084716 733 5744
USF1 HepG2E 44082725 44083722 997 4618
hScc1 BcellGSE12603 44083581 44084042 461 5206
hScc1 CdLSGSE12603 44083800 44085461 1661 6025
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 44073652 44074432 780 0
CTCF G2GSE9613 44075596 44076603 1007 0
Rb GrowingGSE19898 44077946 44078232 286 0
hScc1 BcellGSE12603 44075158 44076765 1607 0
hScc1 CdLSGSE12603 44075534 44076603 1069 0
hScc1 G2GSE9613 44075681 44076765 1084 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1 hsa-mir-1-2 18 20422465
hsa-miR-1 hsa-mir-1-1 20 20422465
hsa-miR-132 hsa-mir-132 17 21057503
hsa-miR-132* hsa-mir-132 17 21057503
hsa-miR-143 hsa-mir-143 5 20089806
hsa-miR-143* hsa-mir-143 5 20089806
hsa-miR-145 hsa-mir-145 5 20089806
hsa-miR-145* hsa-mir-145 5 20089806
hsa-miR-17 hsa-mir-17 13 19155294
hsa-miR-17* hsa-mir-17 13 19155294
hsa-miR-181a hsa-mir-181a-2 9 20023698
hsa-miR-181a hsa-mir-181a-1 1 20023698
hsa-miR-181a* hsa-mir-181a-1 1 20023698
hsa-miR-181a-2* hsa-mir-181a-2 9 20023698
hsa-miR-181b hsa-mir-181b-1 1 20023698
hsa-miR-181b hsa-mir-181b-2 9 20023698
hsa-miR-181c hsa-mir-181c 19 20422465
hsa-miR-181c hsa-mir-181c 19 20023698
hsa-miR-181c* hsa-mir-181c 19 20422465
hsa-miR-181c* hsa-mir-181c 19 20023698
hsa-miR-181d hsa-mir-181d 19 20023698
hsa-miR-188-3p hsa-mir-188 X 19669742
hsa-miR-188-5p hsa-mir-188 X 19669742
hsa-miR-206 hsa-mir-206 6 21302623
hsa-miR-21 hsa-mir-21 17 20833132
hsa-miR-21 hsa-mir-21 17 20816946
hsa-miR-21 hsa-mir-21 17 20460539
hsa-miR-21* hsa-mir-21 17 20833132
hsa-miR-21* hsa-mir-21 17 20816946
hsa-miR-21* hsa-mir-21 17 20460539
hsa-miR-212 hsa-mir-212 17 21057503
hsa-miR-218 hsa-mir-218-1 4 20933503
hsa-miR-218 hsa-mir-218-2 5 20933503
hsa-miR-218-1* hsa-mir-218-1 4 20933503
hsa-miR-224 hsa-mir-224 X 19793168
hsa-miR-26a hsa-mir-26a-1 3 20422465
hsa-miR-26a hsa-mir-26a-2 12 20422465
hsa-miR-29b hsa-mir-29b-1 7 21266537
hsa-miR-29b hsa-mir-29b-2 1 21266537
hsa-miR-30d hsa-mir-30d 8 20422465
hsa-miR-30d* hsa-mir-30d 8 20422465
hsa-miR-376b hsa-mir-376b 0 20422465
hsa-miR-451 hsa-mir-451 17 20816946
hsa-miR-92a hsa-mir-92a-1 13 19155294
hsa-miR-92a hsa-mir-92a-2 X 19155294
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
16446 mRNA MMP9 chr20 44070953 44078606 428 mRNA chr20 44075547 44084119Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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