AutismKB 2.0

Annotation Detail for MMP11


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Basic Information Top
Gene Symbol:MMP11 ( SL-3,ST3,STMY3 )
Gene Full Name: matrix metallopeptidase 11 (stromelysin 3)
Band: 22q11.23
Quick LinksEntrez ID:4320; OMIM: 185261; Uniprot ID:MMP11_HUMAN; ENSEMBL ID: ENSG00000099953; HGNC ID: 7157
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
85Cysteine switch (By similarity).
Location(AA) Modifications Resource
Location(AA) Modification Resource
58O-linkedHMM predict
58Phosphoserine(CDC2)HMM predict
58Phosphoserine(CDK)HMM predict
73Phosphoserine(CDC2)HMM predict
74Phosphoserine(CDK)HMM predict
74O-linkedHMM predict
246Phosphoserine(IKK)HMM predict
263Phosphothreonine(PKC)HMM predict
341Phosphoserine(CDC2)HMM predict
420Phosphoserine(CDC2)HMM predict
427Phosphothreonine(PKA)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005940
  • Location:chr22 22445035-22456501
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 22443236 22443368 132 1734
CTCF CD4SISSRdata 22443236 22443368 132 1734
hScc1 BcellGSE12603 22443258 22443430 172 1692
hScc1 CdLSGSE12603 22443258 22443430 172 1692
hScc1 CdLSGSE12603 22444769 22445299 530 2
p130 SenescentGSE19898 22444635 22445003 368 217
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF HelaGSE12889 22448268 22448472 204 0
H3ac HepG2E 22445417 22446201 784 0
KLF4 hESGSE17917 22444876 22445207 331 0
TFAP2C MCF7GSE21234 22453361 22454166 805 0
hScc1 BcellGSE12603 22444831 22445417 586 0
hScc1 BcellGSE12603 22451009 22451610 601 0
hScc1 BcellGSE12603 22452369 22453490 1121 0
hScc1 BcellGSE12603 22455520 22455867 347 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018