Annotation Detail for MOV10

View Evidences	View Variants	View Annotations

Basic Information Top

Gene Symbol:	MOV10 ( DKFZp667O1423,FLJ32791,KIAA1631,fSAP113,gb110 )
Gene Full Name:	Mov10, Moloney leukemia virus 10, homolog (mouse)
Band:	1p13.2
Quick Links	Entrez ID:4343; OMIM: 610742; Uniprot ID:MOV10_HUMAN; ENSEMBL ID: ENSG00000155363; HGNC ID: 7200
Relate to Another Database:	SFARIGene; denovo-db

General

Expression

Regulation

Pathways, Diseases and Drugs

PTM

TF binding site

miRNA targets

Cis-NATs

Post Translation Modification

Top

PTM Sites from Uniprot:6 results
Experimental PTM Sites from dbPTM:2 results
Predicted PTM Sites by profile HMM from dbPTM:27 results

Location(AA)	Modification
148	N6-acetyllysine.
160	Phosphothreonine.
254	Phosphothreonine.
648	DEAG box.
969	Phosphoserine (By similarity).
977	Phosphoserine.

Location(AA)	Modifications	Resource
969	Phosphoserine (By similarity).	Swiss-Prot 53.0
977	Phosphoserine.	Swiss-Prot 53.0

Location(AA)	Modification	Resource
19	Phosphoserine(CDK)	HMM predict
49	Phosphothreonine(CDC2)	HMM predict
162	Phosphoserine(IKK)	HMM predict
164	O-linked	HMM predict
254	Phosphothreonine(CDC2)	HMM predict
390	Phosphoserine(CK1)	HMM predict
403	Phosphoserine(CK1)	HMM predict
446	N-linked	HMM predict
450	N-linked	HMM predict
499	Phosphoserine(CK2)	HMM predict
514	O-linked	HMM predict
605	Phosphotyrosine(INSR)	HMM predict
690	Phosphoserine(CDC2)	HMM predict
708	Phosphothreonine(PKC)	HMM predict
720	Phosphotyrosine(Syk)	HMM predict
747	Sulfotyrosine	HMM predict
802	Phosphothreonine(PKC)	HMM predict
806	Phosphotyrosine(Jak)	HMM predict
823	Phosphoserine(MAPK)	HMM predict
831	Phosphoserine(CDC2)	HMM predict
886	Phosphoserine(IKK)	HMM predict
969	Phosphoserine(CDC2)	HMM predict
971	O-linked	HMM predict
972	O-linked	HMM predict
973	Phosphoserine(CK1)	HMM predict
973	Phosphoserine(ATM)	HMM predict
980	Phosphotyrosine(Syk)	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_020963
Location:chr1 113018989-113044879
strand:+

Upstream the gene:5 results
Downstream the gene:0 results
Inside the gene:17 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ER	E2-MCF7	GSE14664	113018712	113018748	36	260
ER	Fulvestrant-MCF7	GSE14664	113018709	113018746	37	262
H3ac	HepG2	E	113018781	113019020	239	89
Oct1	Hela	GSE14283	113018709	113018744	35	263
RARA	MCF7	GSE15244	113016804	113018696	1892	1240

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	G2	GSE9613	113019020	113019542	522
H3K4me3	colorectal	cancer	113020385	113020557	172
H3ac	HepG2	E	113020314	113020557	243
Oct1	H2O2-Hela	GSE14283	113035480	113035508	28
Oct1	H2O2-Hela	GSE14283	113038093	113038124	31
Oct1	Hela	GSE14283	113044429	113044476	47
RARA	MCF7	GSE15244	113042701	113043038	337
TAF	k562	GSE8489	113020314	113020557	243
TFAP2C	MCF7	GSE21234	113031405	113031867	462
TFAP2C	MCF7	GSE21234	113042909	113043499	590
USF1	HepG2	E	113042524	113043038	514
USF1	HepG2	E	113043561	113043967	406
USF2	HepG2	E	113042463	113043038	575
hScc1	Bcell	GSE12603	113019093	113019613	520
hScc1	CdLS	GSE12603	113019220	113019638	418
hScc1	G2	GSE9613	113018983	113019574	591
p63	keratinocytes	GSE17611	113031074	113032168	1094

Validated miRNA targets

Top

miR Walk:78 results
Tarbase V5.0:1 results

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7a	hsa-let-7a-1	9	19898466
hsa-let-7a	hsa-let-7a-2	11	19898466
hsa-let-7a	hsa-let-7a-3	22	19898466
hsa-let-7a	hsa-let-7a-1	9	17167072
hsa-let-7a	hsa-let-7a-2	11	17167072
hsa-let-7a	hsa-let-7a-3	22	17167072
hsa-let-7a*	hsa-let-7a-1	9	19898466
hsa-let-7a*	hsa-let-7a-3	22	19898466
hsa-let-7a*	hsa-let-7a-1	9	17167072
hsa-let-7a*	hsa-let-7a-3	22	17167072
hsa-let-7b	hsa-let-7b	22	19898466
hsa-let-7b	hsa-let-7b	22	17167072
hsa-let-7b	hsa-let-7b	22	18668040
hsa-let-7b*	hsa-let-7b	22	19898466
hsa-let-7b*	hsa-let-7b	22	17167072
hsa-let-7b*	hsa-let-7b	22	18668040
hsa-let-7c	hsa-let-7c	21	19898466
hsa-let-7c	hsa-let-7c	21	17167072
hsa-let-7c*	hsa-let-7c	21	19898466
hsa-let-7c*	hsa-let-7c	21	17167072
hsa-let-7d	hsa-let-7d	9	19898466
hsa-let-7d	hsa-let-7d	9	17167072
hsa-let-7d*	hsa-let-7d	9	19898466
hsa-let-7d*	hsa-let-7d	9	17167072
hsa-let-7e	hsa-let-7e	19	19898466
hsa-let-7e	hsa-let-7e	19	17167072
hsa-let-7e*	hsa-let-7e	19	19898466
hsa-let-7e*	hsa-let-7e	19	17167072
hsa-let-7f	hsa-let-7f-1	9	19898466
hsa-let-7f	hsa-let-7f-2	X	19898466
hsa-let-7f	hsa-let-7f-1	9	17167072
hsa-let-7f	hsa-let-7f-2	X	17167072
hsa-let-7f-1*	hsa-let-7f-1	9	19898466
hsa-let-7f-1*	hsa-let-7f-1	9	17167072
hsa-let-7f-2*	hsa-let-7f-2	X	19898466
hsa-let-7f-2*	hsa-let-7f-2	X	17167072
hsa-let-7g	hsa-let-7g	3	19898466
hsa-let-7g	hsa-let-7g	3	17167072
hsa-let-7g*	hsa-let-7g	3	19898466
hsa-let-7g*	hsa-let-7g	3	17167072
hsa-let-7i	hsa-let-7i	12	19898466
hsa-let-7i	hsa-let-7i	12	17167072
hsa-let-7i*	hsa-let-7i	12	19898466
hsa-let-7i*	hsa-let-7i	12	17167072
hsa-miR-1	hsa-mir-1-2	18	18668040
hsa-miR-1	hsa-mir-1-1	20	18668040
hsa-miR-124	hsa-mir-124-1	8	19898466
hsa-miR-124	hsa-mir-124-2	8	19898466
hsa-miR-124	hsa-mir-124-3	20	19898466
hsa-miR-124	hsa-mir-124-1	8	17167072
hsa-miR-124	hsa-mir-124-2	8	17167072
hsa-miR-124	hsa-mir-124-3	20	17167072
hsa-miR-125a-3p	hsa-mir-125a	19	17167072
hsa-miR-125a-5p	hsa-mir-125a	19	17167072
hsa-miR-125b	hsa-mir-125b-1	11	17167072
hsa-miR-125b	hsa-mir-125b-2	21	17167072
hsa-miR-125b-1*	hsa-mir-125b-1	11	17167072
hsa-miR-125b-2*	hsa-mir-125b-2	21	17167072
hsa-miR-128	hsa-mir-128-1	2	17167072
hsa-miR-128	hsa-mir-128-2	3	17167072
hsa-miR-138	hsa-mir-138-2	16	20064393
hsa-miR-138	hsa-mir-138-1	3	20064393
hsa-miR-155	hsa-mir-155	21	18668040
hsa-miR-155*	hsa-mir-155	21	18668040
hsa-miR-16	hsa-mir-16-1	13	18668040
hsa-miR-16	hsa-mir-16-2	3	18668040
hsa-miR-30a	hsa-mir-30a	6	18668040
hsa-miR-30a*	hsa-mir-30a	6	18668040
hsa-miR-30b	hsa-mir-30b	8	18668040
hsa-miR-30b*	hsa-mir-30b	8	18668040
hsa-miR-30c	hsa-mir-30c-2	6	18668040
hsa-miR-30c	hsa-mir-30c-1	1	18668040
hsa-miR-30c-1*	hsa-mir-30c-1	1	18668040
hsa-miR-30c-2*	hsa-mir-30c-2	6	18668040
hsa-miR-30d	hsa-mir-30d	8	18668040
hsa-miR-30d*	hsa-mir-30d	8	18668040
hsa-miR-30e	hsa-mir-30e	1	18668040
hsa-miR-30e*	hsa-mir-30e	1	18668040

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
1170	Unknown	pSILAC	miR-1	MOV10	down 50-25%	18668040
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000155363		n_a	n_a	n_a	"squamous cell, lymphocyte, muscle cell"	"malignant tumour, carcinoma, leukaemia, sarcoma, benign tumour"

Cis-Nats regulation

Top

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
1305	mRNA	MOV10	chr1	112929508	112955399	147	EST		chr1	112948351	112949430	Sense/Antisense (SA) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

AutismKB 2.0

Annotation Detail for MOV10

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics