Annotation Detail for MPG

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Basic Information Top

Gene Symbol:	MPG ( AAG,ADPG,APNG,CRA36.1,MDG,Mid1,PIG11,PIG16,anpg )
Gene Full Name:	N-methylpurine-DNA glycosylase
Band:	16p13.3
Quick Links	Entrez ID:4350; OMIM: 156565; Uniprot ID:3MG_HUMAN; ENSEMBL ID: ENSG00000103152; HGNC ID: 7211
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:2 results
Experimental PTM Sites from dbPTM:2 results
Predicted PTM Sites by profile HMM from dbPTM:14 results

Location(AA)	Modification
78	Phosphoserine.
252	Phosphoserine.

Location(AA)	Modification	Resource
47	Phosphoserine(IKK)	HMM predict
67	Phosphothreonine(MAPK)	HMM predict
113	N-linked	HMM predict
127	Phosphotyrosine(Syk)	HMM predict
143	Phosphothreonine(MAPK)	HMM predict
143	Phosphothreonine(PKC)	HMM predict
143	Phosphothreonine(CDC2)	HMM predict
157	Phosphotyrosine(Jak)	HMM predict
169	N-linked	HMM predict
172	Phosphoserine(ATM)	HMM predict
192	Phosphothreonine(PKC)	HMM predict
199	Phosphothreonine(PKC)	HMM predict
280	Phenylalanine	HMM predict
291	Valine	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_001015052
Location:chr16 68168-75840
strand:+

Upstream the gene:0 results
Downstream the gene:0 results
Inside the gene:5 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CBP	Jurkat	GSE17954	73880	75755	1875	0
CBP	T30-glioblastoma	GSE21026	74477	75296	819	0
NFkBII	GM10847	GSE19485	67623	68911	1288	0
Rb	shRbSenescence	GSE19898	74489	74700	211	0
hScc1	Bcell	GSE12603	68102	69864	1762	0

Validated miRNA targets

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
9415	mRNA	MPG	chr16	68259	75845	27	mRNA	C16orf35	chr16	74272	128859	Sense/Antisense (SA) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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