AutismKB 2.0

Annotation Detail for MPO


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Basic Information Top
Gene Symbol:MPO ( - )
Gene Full Name: myeloperoxidase
Band: 17q22
Quick LinksEntrez ID:4353; OMIM: 606989; Uniprot ID:PERM_HUMAN; ENSEMBL ID: ENSG00000005381; HGNC ID: 7218
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
139N-linked (GlcNAc...).
316Cysteine sulfenic acid (-SOH).
323N-linked (GlcNAc...).
355N-linked (GlcNAc...).
391N-linked (GlcNAc...).
483N-linked (GlcNAc...).
729N-linked (GlcNAc...).
Location(AA) Modifications Resource
139N-linked (GlcNAc...).Swiss-Prot 53.0
316Cysteine sulfenic acid (-SOH).Swiss-Prot 53.0
323N-linked (GlcNAc...).Swiss-Prot 53.0
355N-linked (GlcNAc...).Swiss-Prot 53.0
391N-linked (GlcNAc...).Swiss-Prot 53.0
483N-linked (GlcNAc...)./FTId=CAR
Location(AA) Modification Resource
42Phosphothreonine(MAPK)HMM predict
46O-linkedHMM predict
60Phosphoserine(IKK)HMM predict
83Phosphoserine(PKG)HMM predict
83Phosphoserine(PKA)HMM predict
83Phosphoserine(PKC)HMM predict
90Phosphoserine(PKB)HMM predict
92Phosphoserine(IKK)HMM predict
109O-linkedHMM predict
139N-linkedHMM predict
153Phosphoserine(CK1)HMM predict
160Phosphotyrosine(Syk)HMM predict
187Phosphothreonine(PKC)HMM predict
243Phosphothreonine(MAPK)HMM predict
323N-linkedHMM predict
328N-linkedHMM predict
407Phosphoserine(CK2)HMM predict
443Phosphotyrosine(EGFR)HMM predict
478Phosphothreonine(PKC)HMM predict
483N-linkedHMM predict
516Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000250
  • Location:chr17 53702215-53713294
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER Fulvestrant-MCF7GSE14664 53717637 53717694 57 4371
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 53709556 53709722 166 0
CTCF CD4SISSRdata 53709556 53709722 166 0
CTCF G2GSE9613 53708938 53709144 206 0
CTCF G2GSE9613 53709980 53710491 511 0
ER MCF7GSE19013 53708698 53709151 453 0
hScc1 BcellGSE12603 53710591 53710981 390 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018