Annotation Detail for MRE11A

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Basic Information Top

Gene Symbol:	MRE11A ( ATLD,HNGS1,MRE11,MRE11B )
Gene Full Name:	MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
Band:	11q21
Quick Links	Entrez ID:4361; OMIM: 600814; Uniprot ID:MRE11_HUMAN; ENSEMBL ID: ENSG00000020922; HGNC ID:
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
LIN9	S	GSE7516	93866305	93867106	801	18
Rb	Growing	GSE19898	93866367	93867104	737	48
Rb	Quiescent	GSE19898	93866355	93867028	673	4
p130	Quiescent	GSE19898	93866315	93867151	836	46
p130	Senescent	GSE19898	93866030	93867439	1409	47
p130	shRbQuiescent	GSE19898	93866055	93867428	1373	54

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
E2F4	G0	GSE7516	93866215	93867070	855
ER	E2-MCF7	GSE14664	93808169	93808204	35
ER	Fulvestrant-MCF7	GSE14664	93808159	93808200	41
FOXA1	DLD1	GSE12801	93805661	93806279	618
FOXA1	MCF7	GSE15244	93866305	93866900	595
FoxA1	MCF7	MACSdata	93822218	93822439	221
H3K4me3	colorectal	cancer	93865477	93866747	1270
LIN54	G0	GSE7516	93866246	93867036	790
LIN9	G0	GSE7516	93866024	93867036	1012
Nanog	hES	GSE18292	93846067	93846625	558
Oct1	H2O2-Hela	GSE14283	93820224	93820253	29
Oct1	H2O2-Hela	GSE14283	93858595	93858631	36
Oct1	Hela	GSE14283	93797063	93797090	27
Oct1	Hela	GSE14283	93808167	93808241	74
Oct1	Hela	GSE14283	93820223	93820253	30
Oct1	Hela	GSE14283	93831675	93831704	29
Oct1	Hela	GSE14283	93851863	93851893	30
Oct1	Hela	GSE14283	93858594	93858631	37
Oct1	Hela	GSE14283	93858743	93858776	33
Rb	Quiescent	GSE19898	93866092	93866340	248
Rb	Senescent	GSE19898	93866245	93867088	843
Rb	shRbSenescence	GSE19898	93866427	93866763	336
hScc1	Bcell	GSE12603	93866246	93867036	790
p130	shRbSenescent	GSE19898	93866073	93867243	1170
p130	G0	GSE7516	93866179	93867070	891
p130	S	GSE7516	93866063	93867007	944
p63	keratinocytes	GSE17611	93821953	93822872	919

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-miR-125a-3p	hsa-mir-125a	19	19950226
hsa-miR-125a-3p	hsa-mir-125a	19	19950226
hsa-miR-125a-5p	hsa-mir-125a	19	19950226
hsa-miR-125a-5p	hsa-mir-125a	19	19950226
hsa-miR-140-3p	hsa-mir-140	16	19950226
hsa-miR-140-3p	hsa-mir-140	16	19950226
hsa-miR-140-5p	hsa-mir-140	16	19950226
hsa-miR-140-5p	hsa-mir-140	16	19950226
hsa-miR-149	hsa-mir-149	2	19950226
hsa-miR-149	hsa-mir-149	2	19950226
hsa-miR-149*	hsa-mir-149	2	19950226
hsa-miR-149*	hsa-mir-149	2	19950226
hsa-miR-27a	hsa-mir-27a	19	19950226
hsa-miR-27a	hsa-mir-27a	19	19950226
hsa-miR-27a*	hsa-mir-27a	19	19950226
hsa-miR-27a*	hsa-mir-27a	19	19950226
hsa-miR-423-3p	hsa-mir-423	17	19950226
hsa-miR-423-3p	hsa-mir-423	17	19950226
hsa-miR-423-5p	hsa-mir-423	17	19950226
hsa-miR-423-5p	hsa-mir-423	17	19950226
hsa-miR-92a	hsa-mir-92a-1	13	19950226
hsa-miR-92a	hsa-mir-92a-1	13	19950226
hsa-miR-92a-1*	hsa-mir-92a-1	13	19950226
hsa-miR-92a-1*	hsa-mir-92a-1	13	19950226

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
5048	EST	FGIF	chr11	93866442	93869698	191	mRNA	MRE11A	chr11	93790120	93866688	Sense/Antisense (SA) pairs

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018