AutismKB 2.0

Annotation Detail for MSH3


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Basic Information Top
Gene Symbol:MSH3 ( DUP,MGC163306,MGC163308,MRP1 )
Gene Full Name: mutS homolog 3 (E. coli)
Band: 5q14.1
Quick LinksEntrez ID:4437; OMIM: 600887; Uniprot ID:MSH3_HUMAN; ENSEMBL ID: ENSG00000113318; HGNC ID: 7326
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
201Phosphoserine.
1068Phosphotyrosine.
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002439
  • Location:chr5 79986049-80208388
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 80216637 80217053 416 8457
TFAP2C MCF7GSE21234 80209426 80210032 606 1341
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-134 hsa-mir-134 14 20371173
hsa-miR-379 hsa-mir-379 14 20371173
hsa-miR-379* hsa-mir-379 14 20371173
hsa-miR-495 hsa-mir-495 14 20371173
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
21174 mRNA MSH3 chr5 79986294 80208389 217 mRNA DHFR chr5 79957803 79986572Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018