AutismKB 2.0

Annotation Detail for MSH3


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Basic Information Top
Gene Symbol:MSH3 ( DUP,MGC163306,MGC163308,MRP1 )
Gene Full Name: mutS homolog 3 (E. coli)
Band: 5q14.1
Quick LinksEntrez ID:4437; OMIM: 600887; Uniprot ID:MSH3_HUMAN; ENSEMBL ID: ENSG00000113318; HGNC ID: 7326
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
201Phosphoserine.
1068Phosphotyrosine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
15O-linkedHMM predict
37O-linkedHMM predict
38Phosphoserine(CK1)HMM predict
39Phosphoserine(CK1)HMM predict
41O-linkedHMM predict
131Phosphoserine(CAMK2)HMM predict
149O-linkedHMM predict
186Phosphoserine(CK1)HMM predict
201Phosphoserine(ATM)HMM predict
205Phosphoserine(IKK)HMM predict
207N-linkedHMM predict
212N-linkedHMM predict
227Phosphoserine(PKA)HMM predict
229Phosphotyrosine(INSR)HMM predict
230Phosphothreonine(CDK)HMM predict
310O-linkedHMM predict
321N-linkedHMM predict
338Phosphothreonine(PKA)HMM predict
412Phosphoserine(IKK)HMM predict
416Phosphothreonine(PKC)HMM predict
433Phosphoserine(CK2)HMM predict
444Phosphothreonine(PKA)HMM predict
445Phosphoserine(PKA)HMM predict
445Phosphoserine(CK1)HMM predict
445Phosphoserine(PKG)HMM predict
462SulfotyrosineHMM predict
538N-linkedHMM predict
544N-linkedHMM predict
550N-linkedHMM predict
603Phosphoserine(CK1)HMM predict
606Phosphoserine(CK1)HMM predict
680Phosphoserine(MAPK)HMM predict
685Phosphotyrosine(Jak)HMM predict
739N-linkedHMM predict
830Phosphothreonine(PKC)HMM predict
877Phosphotyrosine(INSR)HMM predict
880N-linkedHMM predict
881N-linkedHMM predict
885Phosphoserine(CK2)HMM predict
946Phosphotyrosine(Syk)HMM predict
967Phosphothreonine(PKA)HMM predict
982Phosphoserine(PKB)HMM predict
1039Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002439
  • Location:chr5 79986049-80208388
  • strand:+
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 80216637 80217053 416 8457
TFAP2C MCF7GSE21234 80209426 80210032 606 1341
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 80003856 80004090 234 0
CTCF CD4GSE12889 80018424 80018692 268 0
CTCF CD4SISSRdata 80003856 80004090 234 0
CTCF CD4SISSRdata 80018424 80018692 268 0
CTCF HelaGSE12889 80043629 80043808 179 0
CTCF G2GSE9613 80003609 80004077 468 0
CTCF G2GSE9613 80043529 80043777 248 0
GABP k562GSE8489 80044425 80044598 173 0
NRSF JurkatGSE13047 80185085 80185424 339 0
NRSF mAbJurkat 80187031 80187375 344 0
NRSF-mono JurkatQuESTdata 80185024 80185355 331 0
Nanog ESGSE20650 80152262 80152611 349 0
Nanog hESGSE18292 80018271 80018640 369 0
Nanog hESGSE18292 80079656 80080038 382 0
Oct1 H2O2-HelaGSE14283 79998056 79998091 35 0
Oct1 H2O2-HelaGSE14283 80047451 80047481 30 0
Oct1 HelaGSE14283 80003812 80003858 46 0
Oct1 HelaGSE14283 80118415 80118451 36 0
Sox2 hESGSE18292 80018448 80018625 177 0
Sox2 hESGSE18292 80079386 80080041 655 0
TFAP2C MCF7GSE21234 79999597 80000258 661 0
TFAP2C MCF7GSE21234 80068329 80068671 342 0
hScc1 BcellGSE12603 80003609 80004077 468 0
hScc1 BcellGSE12603 80043529 80043913 384 0
hScc1 CdLSGSE12603 80003609 80004138 529 0
hScc1 CdLSGSE12603 80043529 80043838 309 0
p130 shRbSenescentGSE19898 80203302 80203585 283 0
p63 keratinocytesGSE17611 80154151 80154784 633 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-134 hsa-mir-134 14 20371173
hsa-miR-379 hsa-mir-379 14 20371173
hsa-miR-379* hsa-mir-379 14 20371173
hsa-miR-495 hsa-mir-495 14 20371173
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
21174 mRNA MSH3 chr5 79986294 80208389 217 mRNA DHFR chr5 79957803 79986572Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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