Annotation Detail for MTNR1A

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Basic Information Top

Gene Symbol:	MTNR1A ( MEL-1A-R,MT1 )
Gene Full Name:	melatonin receptor 1A
Band:	4q35.2
Quick Links	Entrez ID:4543; OMIM: 600665; Uniprot ID:MTR1A_HUMAN; ENSEMBL ID: ENSG00000168412; HGNC ID: 7463
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:2 results
Experimental PTM Sites from dbPTM:2 results
Predicted PTM Sites by profile HMM from dbPTM:6 results

Location(AA)	Modification
4	N-linked (GlcNAc...) (Potential).
10	N-linked (GlcNAc...) (Potential).

Location(AA)	Modification	Resource
10	N-linked	HMM predict
12	Phosphoserine(ATM)	HMM predict
117	N-linked	HMM predict
144	Phosphoserine(PKA)	HMM predict
267	Phosphoserine(MAPK)	HMM predict
336	Phosphoserine(CDC2)	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_005958
Location:chr4 187691802-187713530
strand:-

Upstream the gene:2 results
Downstream the gene:0 results
Inside the gene:8 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
hScc1	Bcell	GSE12603	187713361	187713833	472	67
hScc1	G2	GSE9613	187713249	187713833	584	11

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	187692152	187693061	909	0
CTCF	G2	GSE9613	187694536	187694719	183	0
CTCF	G2	GSE9613	187697382	187697568	186	0
CTCF	G2	GSE9613	187704646	187705470	824	0
CTCF	G2	GSE9613	187712661	187713833	1172	0
TAFII	hES	GSE17917	187694568	187694777	209	0
hScc1	Bcell	GSE12603	187704891	187705336	445	0
hScc1	G2	GSE9613	187694536	187694719	183	0

Validated miRNA targets

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
20546	EST		chr4	187797467	187842076	12119	mRNA	MTNR1A	chr4	187829957	187851686	Non-exonic Bidirectional (NOB) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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