AutismKB 2.0

Annotation Detail for MTNR1B


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Basic Information Top
Gene Symbol:MTNR1B ( FGQTL2,MEL-1B-R,MT2 )
Gene Full Name: melatonin receptor 1B
Band: 11q14.3
Quick LinksEntrez ID:4544; OMIM: 600804; Uniprot ID:MTR1B_HUMAN; ENSEMBL ID: ENSG00000134640; HGNC ID: 7464
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
4N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
4N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
9N-linkedHMM predict
31O-linkedHMM predict
130N-linkedHMM predict
197O-linkedHMM predict
201O-linkedHMM predict
249Phosphoserine(IKK)HMM predict
347Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005959
  • Location:chr11 92342436-92355595
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NFkBII GM12878GSE19485 92327870 92329473 1603 13765
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 92372894 92374520 1626 18112
Fos K562GSE19551 92373197 92373680 483 17843
Myc K562GSE19551 92373307 92373672 365 17894
P300 T30-glioblastomaGSE21026 92372998 92374101 1103 17954
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER Fulvestrant-MCF7GSE14664 92344080 92344114 34 0
NRSF JurkatGSE13047 92342559 92342974 415 0
NRSF-mono JurkatQuESTdata 92342501 92342864 363 0
Rb shRbSenescenceGSE19898 92345304 92345496 192 0
Validated miRNA targets Top
Cis-Nats regulation Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018