Annotation Detail for MTRR
Basic Information Top
| Gene Symbol: | MTRR ( MGC129643,MSR,cblE ) |
|---|---|
| Gene Full Name: | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase |
| Band: | 5p15.31 |
| Quick Links | Entrez ID:4552; OMIM: 602568; Uniprot ID:MTRR_HUMAN; ENSEMBL ID: ENSG00000124275; HGNC ID: 7473 |
| Relate to Another Database: | SFARIGene; denovo-db |
| No data |
| No data |
| Location(AA) | Modification | Resource |
|---|---|---|
| 85 | O-linked | HMM predict |
| 89 | O-linked | HMM predict |
| 105 | N-linked | HMM predict |
| 198 | Phosphoserine(MAPK) | HMM predict |
| 242 | N-linked | HMM predict |
| 245 | N-linked | HMM predict |
| 276 | Phosphotyrosine(Jak) | HMM predict |
| 295 | O-linked | HMM predict |
| 349 | Phosphoserine(CK1) | HMM predict |
| 349 | Phosphoserine(IKK) | HMM predict |
| 420 | Phosphoserine(CK2) | HMM predict |
| 466 | Phosphoserine(MAPK) | HMM predict |
| 481 | Phosphoserine(IKK) | HMM predict |
| 550 | Phosphoserine(CDC2) | HMM predict |
| 550 | O-linked | HMM predict |
| 675 | Phosphotyrosine(INSR) | HMM predict |
- RefSeq ID: NM_002454
- Location:chr5 7922274-7954232
- strand:+
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| Oct1 | Hela | GSE14283 | 7957674 | 7957763 | 89 | 3486 |
| Oct1 | Hela | GSE14283 | 7968319 | 7968355 | 36 | 14105 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | CD4 | GSE12889 | 7940259 | 7940568 | 309 | 0 |
| CTCF | CD4 | SISSRdata | 7940259 | 7940568 | 309 | 0 |
| CTCF | G2 | GSE9613 | 7921774 | 7922885 | 1111 | 0 |
| CTCF | G2 | GSE9613 | 7940033 | 7940602 | 569 | 0 |
| CTCF | G2 | GSE9613 | 7949963 | 7950496 | 533 | 0 |
| FOXA1 | MCF7 | GSE15244 | 7931044 | 7932085 | 1041 | 0 |
| H3K4me3 | colorectal | cancer | 7922992 | 7923505 | 513 | 0 |
| H3ac | HepG2 | E | 7922808 | 7924119 | 1311 | 0 |
| PHF8 | HeLa | GSE20725 | 7921174 | 7923436 | 2262 | 0 |
| TFAP2C | MCF7 | GSE21234 | 7931368 | 7932106 | 738 | 0 |
| hScc1 | CdLS | GSE12603 | 7940000 | 7940705 | 705 | 0 |
| Micro RNA Name | Stem Loop Name | The chromosome that miRNA located | Publication |
|---|---|---|---|
| hsa-let-7b | hsa-let-7b | 22 | 18668040 |
| hsa-let-7b* | hsa-let-7b | 22 | 18668040 |
| hsa-miR-1 | hsa-mir-1-2 | 18 | 18668040 |
| hsa-miR-1 | hsa-mir-1-1 | 20 | 18668040 |
| hsa-miR-155 | hsa-mir-155 | 21 | 18668040 |
| hsa-miR-155* | hsa-mir-155 | 21 | 18668040 |
| hsa-miR-16 | hsa-mir-16-1 | 13 | 18668040 |
| hsa-miR-16 | hsa-mir-16-2 | 3 | 18668040 |
| hsa-miR-30a | hsa-mir-30a | 6 | 18668040 |
| hsa-miR-30a* | hsa-mir-30a | 6 | 18668040 |
| hsa-miR-30b | hsa-mir-30b | 8 | 18668040 |
| hsa-miR-30b* | hsa-mir-30b | 8 | 18668040 |
| hsa-miR-30c | hsa-mir-30c-2 | 6 | 18668040 |
| hsa-miR-30c | hsa-mir-30c-1 | 1 | 18668040 |
| hsa-miR-30c-1* | hsa-mir-30c-1 | 1 | 18668040 |
| hsa-miR-30c-2* | hsa-mir-30c-2 | 6 | 18668040 |
| hsa-miR-30d | hsa-mir-30d | 8 | 18668040 |
| hsa-miR-30d* | hsa-mir-30d | 8 | 18668040 |
| hsa-miR-30e | hsa-mir-30e | 1 | 18668040 |
| hsa-miR-30e* | hsa-mir-30e | 1 | 18668040 |
| ID in Tarbase | Data Type | Support Type | miRNA | Gene | Direct Support | Publication |
|---|---|---|---|---|---|---|
| 874 | Unknown | pSILAC | let-7b | MTRR | down 50-25% | 18668040 |
| Ensembl | Protein Type | Differentially expressed in | Pathology or Event | Mis Regulation | Gene Expression | Tumour Involvement |
| ENSG00000124275 | n_a | n_a | n_a | "epithelium, lymphocyte, muscle cell" | "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma" |
Cis-Nats regulation