AutismKB 2.0

Annotation Detail for MYBL2


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Basic Information Top
Gene Symbol:MYBL2 ( B-MYB,BMYB,MGC15600 )
Gene Full Name: v-myb myeloblastosis viral oncogene homolog (avian)-like 2
Band: 20q13.12
Quick LinksEntrez ID:4605; OMIM: 601415; Uniprot ID:MYBB_HUMAN; ENSEMBL ID: ENSG00000101057; HGNC ID: 7548
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
241Phosphoserine.
266Phosphothreonine.
393Phosphoserine.
405Phosphothreonine.
417Nuclear localization signal.
440Phosphothreonine; by CDK2.
444Phosphothreonine; by CDK2.
487Phosphothreonine; by CDK2.
494Phosphothreonine; by CDK2.
520Phosphothreonine; by CDK2.
577Phosphoserine; by CDK2.
584Bipartite nuclear localization signal.
Location(AA) Modifications Resource
266Phosphothreonine.Swiss-Prot 53.0
266PhosphothreoninePhospho.ELM 6.0
393PhosphoserinePhospho.ELM 6.0
393Phosphoserine.Swiss-Prot 53.0
440Phosphothreonine (by CDK2).Swiss-Prot 53.0
444Phosphothreonine (CDK2)Phospho.ELM 6.0
444Phosphothreonine (by CDK2).Swiss-Prot 53.0
487Phosphothreonine (by CDK2).Swiss-Prot 53.0
487Phosphothreonine (CDK2)Phospho.ELM 6.0
494Phosphothreonine (by CDK2).Swiss-Prot 53.0
494Phosphothreonine (CDK2)Phospho.ELM 6.0
520Phosphothreonine (by CDK2).Swiss-Prot 53.0
577Phosphoserine (CDK2)Phospho.ELM 6.0
577Phosphoserine (by CDK2).Swiss-Prot 53.0
Location(AA) Modification Resource
15SulfotyrosineHMM predict
15Phosphotyrosine(Syk)HMM predict
63N-linkedHMM predict
177N-linkedHMM predict
241Phosphoserine(CK2)HMM predict
241Phosphoserine(CK1)HMM predict
250Phosphothreonine(PKC)HMM predict
266Phosphothreonine(CDK)HMM predict
266Phosphothreonine(MAPK)HMM predict
282Phosphoserine(IKK)HMM predict
339Phosphoserine(IKK)HMM predict
341N-linkedHMM predict
342N-linkedHMM predict
393Phosphoserine(CDC2)HMM predict
401O-linkedHMM predict
405Phosphothreonine(MAPK)HMM predict
421Phosphoserine(CDC2)HMM predict
426N-linkedHMM predict
431Phosphoserine(IKK)HMM predict
440Phosphothreonine(MAPK)HMM predict
440Phosphothreonine(CDK)HMM predict
444Phosphothreonine(CDK)HMM predict
448O-linkedHMM predict
448Phosphothreonine(PKC)HMM predict
452Phosphoserine(ATM)HMM predict
472Phosphoserine(IKK)HMM predict
472Phosphoserine(CK1)HMM predict
472O-linkedHMM predict
474O-linkedHMM predict
475O-linkedHMM predict
476O-linkedHMM predict
480O-linkedHMM predict
487Phosphothreonine(MAPK)HMM predict
487Phosphothreonine(CDK)HMM predict
494Phosphothreonine(CDK)HMM predict
494Phosphothreonine(MAPK)HMM predict
505Phosphothreonine(MAPK)HMM predict
505Phosphothreonine(CDC2)HMM predict
518Phosphothreonine(MAPK)HMM predict
520Phosphothreonine(CDK)HMM predict
538Phosphothreonine(MAPK)HMM predict
577Phosphoserine(CDC2)HMM predict
577Phosphoserine(CDK)HMM predict
605O-linkedHMM predict
607Phosphoserine(IKK)HMM predict
610O-linkedHMM predict
611O-linkedHMM predict
614O-linkedHMM predict
615N-linkedHMM predict
618Phosphoserine(CK1)HMM predict
618O-linkedHMM predict
629Phosphoserine(CK1)HMM predict
655Phosphothreonine(CDC2)HMM predict
665Phosphothreonine(PKC)HMM predict
688LeucineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002466
  • Location:chr20 41729122-41778535
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 41719070 41720242 1172 9467
H3ac HepG2E 41719250 41719516 266 9740
H3ac HepG2E 41719952 41720456 504 8919
NFkBII GM12892GSE19485 41718902 41720295 1393 9524
NFkBII GM18526GSE19485 41718776 41720344 1568 9563
Oct4 hESGSE17917 41719394 41719789 395 9531
P300 T30-glioblastomaGSE21026 41719068 41720603 1535 9287
PHF8 293TGSE20725 41718987 41720208 1221 9525
PHF8 HeLaGSE20725 41718927 41720204 1277 9557
Rb SenescentGSE19898 41728923 41729233 310 45
TAFII hESGSE17917 41719481 41719783 302 9491
hScc1 BcellGSE12603 41719250 41719799 549 9598
p130 SenescentGSE19898 41719428 41720201 773 9308
p130 SenescentGSE19898 41728911 41729253 342 41
p130 shRbQuiescentGSE19898 41719143 41720190 1047 9456
p130 shRbSenescentGSE19898 41719458 41720273 815 9257
p130 shRbSenescentGSE19898 41720332 41720475 143 8719
p130 shRbSenescentGSE19898 41728879 41729233 354 67
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Gata2 K562GSE18868 41752973 41753366 393 0
Myc K562GSE19551 41739126 41739481 355 0
PHF8 HeLaGSE20725 41728535 41729798 1263 0
Rb QuiescentGSE19898 41729071 41729261 190 0
Rb SenescentGSE19898 41729423 41729861 438 0
Stat6 IL-4-hr4GSE17850 41748272 41748841 569 0
hScc1 BcellGSE12603 41728703 41729613 910 0
hScc1 BcellGSE12603 41743186 41743767 581 0
hScc1 BcellGSE12603 41754274 41754529 255 0
p130 QuiescentGSE19898 41729029 41729249 220 0
p130 QuiescentGSE19898 41729329 41729468 139 0
p130 SenescentGSE19898 41729385 41729634 249 0
p130 shRbQuiescentGSE19898 41728974 41729374 400 0
p130 shRbSenescentGSE19898 41729419 41729782 363 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-149 hsa-mir-149 2 20623644
hsa-miR-149* hsa-mir-149 2 20623644
hsa-miR-29a hsa-mir-29a 7 21187425
hsa-miR-29a* hsa-mir-29a 7 21187425
hsa-miR-29b hsa-mir-29b-1 7 21187425
hsa-miR-29b hsa-mir-29b-2 1 21187425
hsa-miR-29b-1* hsa-mir-29b-1 7 21187425
hsa-miR-29b-2* hsa-mir-29b-2 1 21187425
hsa-miR-29c hsa-mir-29c 1 21187425
hsa-miR-29c* hsa-mir-29c 1 21187425
hsa-miR-30a hsa-mir-30a 6 21187425
hsa-miR-30a* hsa-mir-30a 6 21187425
hsa-miR-30b hsa-mir-30b 8 21187425
hsa-miR-30b* hsa-mir-30b 8 21187425
hsa-miR-30c hsa-mir-30c-2 6 21187425
hsa-miR-30c hsa-mir-30c-1 1 21187425
hsa-miR-30c-1* hsa-mir-30c-1 1 21187425
hsa-miR-30c-2* hsa-mir-30c-2 6 21187425
hsa-miR-30d hsa-mir-30d 8 21187425
hsa-miR-30d* hsa-mir-30d 8 21187425
hsa-miR-30e hsa-mir-30e 1 21187425
hsa-miR-30e* hsa-mir-30e 1 21187425
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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