AutismKB 2.0

Annotation Detail for MYBPC3


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Basic Information Top
Gene Symbol:MYBPC3 ( CMH4,DKFZp779E1762,FHC,MYBP-C )
Gene Full Name: myosin binding protein C, cardiac
Band: 11p11.2
Quick LinksEntrez ID:4607; OMIM: 600958; Uniprot ID:MYPC3_HUMAN; ENSEMBL ID: ENSG00000134571; HGNC ID: 7551
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
1N-acetylmethionine (By similarity).
275Phosphoserine; by PKA and PKC (By
284Phosphoserine; by PKA and PKC (By
304Phosphoserine; by PKA and PKC (By
Location(AA) Modifications Resource
275Phosphoserine (by PKA and PKC) (Bysimilarity).Swiss-Prot 53.0
284Phosphoserine (by PKA and PKC) (Bysimilarity).Swiss-Prot 53.0
304Phosphoserine (by PKA and PKC) (Bysimilarity).Swiss-Prot 53.0
Location(AA) Modification Resource
33Phosphothreonine(PKC)HMM predict
133Phosphoserine(MAPK)HMM predict
133Phosphoserine(CDK)HMM predict
133O-linkedHMM predict
133Phosphoserine(CDC2)HMM predict
201Phosphoserine(CK1)HMM predict
253N-linkedHMM predict
275Phosphoserine(PKA)HMM predict
275Phosphoserine(PKG)HMM predict
275Phosphoserine(PKC)HMM predict
284Phosphoserine(PKG)HMM predict
307Phosphothreonine(CDC2)HMM predict
333Phosphotyrosine(Syk)HMM predict
433Phosphotyrosine(EGFR)HMM predict
613SulfotyrosineHMM predict
728Phosphothreonine(PKC)HMM predict
748Phosphotyrosine(SRC)HMM predict
762N-linkedHMM predict
796Phosphotyrosine(INSR)HMM predict
796Phosphotyrosine(Abl)HMM predict
841Phosphotyrosine(Abl)HMM predict
857Phosphoserine(MAPK)HMM predict
857Phosphoserine(IKK)HMM predict
860Phosphoserine(IKK)HMM predict
903Phosphotyrosine(INSR)HMM predict
956O-linkedHMM predict
957O-linkedHMM predict
1023Phosphoserine(CDC2)HMM predict
1042Phosphotyrosine(SRC)HMM predict
1045Phosphothreonine(PKC)HMM predict
1152Phosphothreonine(PKC)HMM predict
1181Phosphoserine(IKK)HMM predict
1206Phosphoserine(CDC2)HMM predict
1250Phosphotyrosine(INSR)HMM predict
1265S-farnesylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000256
  • Location:chr11 47309526-47330797
  • strand:-
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF JurkatGSE12889 47327132 47327267 135 0
NRSF pAbJurkat 47319417 47319771 354 0
NRSF pAbJurkat 47329087 47329904 817 0
TAF HelaGSE8489 47313987 47314307 320 0
TFAP2C MCF7GSE21234 47309632 47310497 865 0
hScc1 BcellGSE12603 47309955 47310344 389 0
hScc1 BcellGSE12603 47327753 47328228 475 0
hScc1 G2GSE9613 47327863 47328228 365 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018