AutismKB 2.0

Annotation Detail for MYH11


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Basic Information Top
Gene Symbol:MYH11 ( AAT4,DKFZp686D10126,DKFZp686D19237,FAA4,FLJ35232,MGC126726,MGC32963,SMHC,SMMHC )
Gene Full Name: myosin, heavy chain 11, smooth muscle
Band: 16p13.11
Quick LinksEntrez ID:4629; OMIM: 160745; Uniprot ID:MYH11_HUMAN; ENSEMBL ID: ENSG00000133392; HGNC ID: 7569
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
129N6,N6,N6-trimethyllysine (Potential).
1539Phosphothreonine.
1546Phosphothreonine.
1954Phosphoserine.
Location(AA) Modifications Resource
129N6,N6,N6-trimethyllysine (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
8Phosphoserine(CK2)HMM predict
8Phosphoserine(CK2)HMM predict
23Phosphoserine(CDC2)HMM predict
70Phosphothreonine(PKC)HMM predict
208Phosphothreonine(PKA)HMM predict
238N-linkedHMM predict
306N-linkedHMM predict
312N-linkedHMM predict
371Phosphoserine(IKK)HMM predict
388N-linkedHMM predict
413Phosphothreonine(CK2)HMM predict
477N-linkedHMM predict
480N-linkedHMM predict
488N-linkedHMM predict
499Phosphotyrosine(Syk)HMM predict
587N-linkedHMM predict
602N-linkedHMM predict
608N-linkedHMM predict
641O-linkedHMM predict
670N-linkedHMM predict
674N-linkedHMM predict
883Phosphoserine(IKK)HMM predict
883Phosphoserine(ATM)HMM predict
903Phosphotyrosine(INSR)HMM predict
1009Phosphoserine(CK1)HMM predict
1024N-linkedHMM predict
1030N-linkedHMM predict
1189Phosphoserine(CK1)HMM predict
1228Phosphothreonine(PKC)HMM predict
1312Phosphoserine(CK1)HMM predict
1315Phosphoserine(ATM)HMM predict
1315Phosphoserine(CK1)HMM predict
1347Phosphoserine(CK1)HMM predict
1403N-linkedHMM predict
1408Phosphotyrosine(Syk)HMM predict
1601SulfotyrosineHMM predict
1763Phosphothreonine(PKA)HMM predict
1775Phosphothreonine(PKC)HMM predict
1893Phosphoserine(ATM)HMM predict
1913Phosphoserine(IKK)HMM predict
1932N-linkedHMM predict
1954Phosphoserine(CK2)HMM predict
1966N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002474
  • Location:chr16 15704494-15858387
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 15858281 15858750 469 128
H3K27me3 colorectalcancer 15858888 15859286 398 700
Oct1 HelaGSE14283 15859083 15859118 35 713
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 15813230 15813943 713 0
CTCF CD4GSE12889 15758019 15758213 194 0
CTCF CD4GSE12889 15767238 15767626 388 0
CTCF CD4GSE12889 15823313 15823460 147 0
CTCF CD4SISSRdata 15758019 15758213 194 0
CTCF CD4SISSRdata 15767238 15767626 388 0
CTCF CD4SISSRdata 15823313 15823460 147 0
CTCF HelaGSE12889 15823296 15823488 192 0
CTCF G2GSE9613 15728042 15728526 484 0
CTCF G2GSE9613 15757481 15758118 637 0
CTCF G2GSE9613 15778852 15779506 654 0
CTCF G2GSE9613 15785370 15785686 316 0
CTCF G2GSE9613 15804919 15805253 334 0
CTCF G2GSE9613 15810275 15810563 288 0
CTCF G2GSE9613 15811800 15812035 235 0
CTCF G2GSE9613 15850104 15850404 300 0
ER E2-MCF7GSE14664 15805750 15805793 43 0
ER Fulvestrant-MCF7GSE14664 15756369 15756418 49 0
Fos K562GSE19551 15776485 15776933 448 0
FoxA1 MCF7MACSdata 15746579 15746808 229 0
H3K27me3 colorectalcancer 15857022 15858352 1330 0
Myc K562GSE19551 15779218 15779648 430 0
NRSF JurkatSISSRdata 15767326 15767516 190 0
NRSF mAbJurkat 15766186 15766442 256 0
NRSF mAbJurkat 15766872 15767222 350 0
NRSF mAbJurkat 15810385 15810563 178 0
NRSF pAbJurkat 15810275 15810563 288 0
Nanog hESGSE18292 15737974 15738324 350 0
Oct1 HelaGSE14283 15746567 15746631 64 0
Oct1 HelaGSE14283 15805757 15805788 31 0
Oct1 HelaGSE14283 15814091 15814123 32 0
Oct1 HelaGSE14283 15824225 15824258 33 0
Oct1 HelaGSE14283 15834333 15834367 34 0
P300 T30-glioblastomaGSE21026 15813171 15813901 730 0
Rb GrowingGSE19898 15813602 15813798 196 0
TAF HelaGSE8489 15800602 15801226 624 0
TFAP2C MCF7GSE21234 15746361 15746795 434 0
USF1 HepG2E 15783723 15786201 2478 0
hScc1 BcellGSE12603 15757481 15758118 637 0
hScc1 BcellGSE12603 15766872 15767222 350 0
hScc1 BcellGSE12603 15779021 15779543 522 0
hScc1 CdLSGSE12603 15757829 15758118 289 0
hScc1 CdLSGSE12603 15779292 15779649 357 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-143 hsa-mir-143 5 20089806
hsa-miR-143* hsa-mir-143 5 20089806
hsa-miR-145 hsa-mir-145 5 20089806
hsa-miR-145* hsa-mir-145 5 20089806
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
9663 mRNA NDE1 chr16 15651604 15726490 477 mRNA MYH11 chr16 15704494 15858369Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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