AutismKB 2.0

Annotation Detail for MYO1E


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Basic Information Top
Gene Symbol:MYO1E ( HuncM-IC,MGC104638,MYO1C )
Gene Full Name: myosin IE
Band: 15q22.2
Quick LinksEntrez ID:4643; OMIM: 601479; Uniprot ID:MYO1E_HUMAN; ENSEMBL ID: ENSG00000157483; HGNC ID: 7599
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
980Phosphoserine.
Location(AA) Modifications Resource
736PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
43Phosphotyrosine(Syk)HMM predict
82Phosphotyrosine(Syk)HMM predict
119Phosphothreonine(PKC)HMM predict
165N-linkedHMM predict
166N-linkedHMM predict
179Phosphoserine(CDC2)HMM predict
226Phosphoserine(IKK)HMM predict
236SulfotyrosineHMM predict
428Phosphotyrosine(INSR)HMM predict
559Phosphothreonine(PKA)HMM predict
590N-linkedHMM predict
736Phosphoserine(PKG)HMM predict
745SulfotyrosineHMM predict
745Phosphotyrosine(INSR)HMM predict
823Phosphoserine(CK1)HMM predict
825Phosphoserine(IKK)HMM predict
841Phosphotyrosine(EGFR)HMM predict
932Phosphothreonine(PKC)HMM predict
935N-linkedHMM predict
936Phosphothreonine(PKA)HMM predict
939N-linkedHMM predict
940O-linkedHMM predict
942Phosphotyrosine(Jak)HMM predict
943O-linkedHMM predict
981Phosphoserine(ATM)HMM predict
990Phosphotyrosine(INSR)HMM predict
1003Phosphoserine(PKG)HMM predict
1003Phosphoserine(IKK)HMM predict
1005Phosphoserine(CK1)HMM predict
1006Phosphoserine(ATM)HMM predict
1010Phosphoserine(PKG)HMM predict
1012Phosphothreonine(MAPK)HMM predict
1033Phosphothreonine(PKC)HMM predict
1033Phosphothreonine(PKA)HMM predict
1034Phosphothreonine(PKC)HMM predict
1035O-linkedHMM predict
1093ArginineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004998
  • Location:chr15 57215855-57452362
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 57451984 57453267 1283 263
P300 T30-glioblastomaGSE21026 57468071 57468553 482 15950
Sox2 hESGSE18292 57452558 57452776 218 305
TAF HelaGSE8489 57452305 57453121 816 351
hScc1 BcellGSE12603 57456342 57456646 304 4132
p130 SenescentGSE19898 57452379 57452827 448 241
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 57217614 57217977 363 0
CTCF CD4GSE12889 57254358 57254617 259 0
CTCF CD4GSE12889 57326931 57327197 266 0
CTCF CD4SISSRdata 57217614 57217977 363 0
CTCF CD4SISSRdata 57254358 57254617 259 0
CTCF CD4SISSRdata 57326931 57327197 266 0
CTCF JurkatGSE12889 57217738 57217988 250 0
CTCF G2GSE9613 57217712 57218206 494 0
CTCF G2GSE9613 57240556 57240933 377 0
FoxA1 MCF7MACSdata 57363619 57363795 176 0
H3K4me3 colorectalcancer 57450178 57450960 782 0
Myc K562GSE19551 57217573 57218205 632 0
NFkBII GM12878GSE19485 57391311 57394367 3056 0
Nanog hESGSE18292 57433396 57433993 597 0
Oct1 H2O2-HelaGSE14283 57247298 57247326 28 0
Oct1 H2O2-HelaGSE14283 57311703 57311742 39 0
Oct1 HelaGSE14283 57289450 57289479 29 0
Oct1 HelaGSE14283 57358811 57358869 58 0
Oct4 hESGSE17917 57240805 57241023 218 0
Pol2 GM12878GSE19551 57451846 57452691 845 0
Rb GrowingGSE19898 57412973 57413232 259 0
Rb SenescentGSE19898 57271418 57271753 335 0
STAT1 HeLaGSE12783 57219843 57221159 1316 0
STAT1 HeLaGSE12783 57428619 57430759 2140 0
Stat6 IL-4-hr1GSE17850 57354926 57355488 562 0
TAF HelaGSE8489 57450780 57451149 369 0
TAFII hESGSE17917 57452028 57452689 661 0
TFAP2C MCF7GSE21234 57356085 57356718 633 0
TFAP2C MCF7GSE21234 57363260 57363953 693 0
TFAP2C MCF7GSE21234 57449912 57450223 311 0
hScc1 BcellGSE12603 57217675 57218060 385 0
hScc1 BcellGSE12603 57222043 57222256 213 0
hScc1 BcellGSE12603 57224085 57224294 209 0
hScc1 BcellGSE12603 57329262 57329398 136 0
hScc1 BcellGSE12603 57379713 57380104 391 0
hScc1 BcellGSE12603 57450526 57452701 2175 0
p130 QuiescentGSE19898 57271491 57271661 170 0
p63 keratinocytesGSE17611 57244759 57245916 1157 0
p63 keratinocytesGSE17611 57418551 57419498 947 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
975 Unknown pSILAC miR-155 MYO1E down 75-50% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000157483 n_a n_a n_a "epithelium, lymphocyte, muscle cell" "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
8882 mRNA LDHAL6B chr15 57286333 57287999 1666 mRNA MYO1E chr15 57215855 57452363 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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