AutismKB 2.0

Annotation Detail for PPP1R12B


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Basic Information Top
Gene Symbol:PPP1R12B ( FLJ40942,MGC131980,MGC87886,MYPT2 )
Gene Full Name: protein phosphatase 1, regulatory (inhibitor) subunit 12B
Band: 1q32.1
Quick LinksEntrez ID:4660; OMIM: 603768; Uniprot ID:MYPT2_HUMAN; ENSEMBL ID: ENSG00000077157; HGNC ID: 7619
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
839Phosphoserine (By similarity).
947Phosphoserine.
Location(AA) Modifications Resource
839Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
51Phosphoserine(CDC2)HMM predict
136Phosphotyrosine(Syk)HMM predict
325Phosphoserine(CK1)HMM predict
357Phosphoserine(CK2)HMM predict
361Phosphoserine(CK2)HMM predict
362Phosphoserine(CK2)HMM predict
362Phosphoserine(CK1)HMM predict
372Phosphoserine(CK2)HMM predict
372Phosphoserine(IKK)HMM predict
372Phosphoserine(CK1)HMM predict
376Phosphothreonine(CK2)HMM predict
389N-linkedHMM predict
391Phosphoserine(IKK)HMM predict
392N-linkedHMM predict
395Phosphoserine(CK1)HMM predict
398Phosphoserine(PKG)HMM predict
398Phosphoserine(IKK)HMM predict
398Phosphoserine(CK1)HMM predict
410O-linkedHMM predict
469Phosphotyrosine(EGFR)HMM predict
471Phosphoserine(CDC2)HMM predict
474Phosphoserine(ATM)HMM predict
474Phosphoserine(CDC2)HMM predict
490N-linkedHMM predict
503N-linkedHMM predict
506Phosphoserine(CK2)HMM predict
549Phosphotyrosine(EGFR)HMM predict
561Phosphoserine(ATM)HMM predict
565Phosphothreonine(CK2)HMM predict
573N-linkedHMM predict
590O-linkedHMM predict
596O-linkedHMM predict
598O-linkedHMM predict
618Phosphoserine(PKG)HMM predict
621Phosphothreonine(CDK)HMM predict
642Phosphothreonine(PKC)HMM predict
642O-linkedHMM predict
646PhosphothreonineHMM predict
646Phosphothreonine(PKA)HMM predict
687Phosphoserine(ATM)HMM predict
694O-linkedHMM predict
732Phosphothreonine(CDK)HMM predict
732Phosphothreonine(MAPK)HMM predict
732Phosphothreonine(CDC2)HMM predict
735Phosphoserine(CDK)HMM predict
735Phosphoserine(CDC2)HMM predict
735O-linkedHMM predict
735Phosphoserine(IKK)HMM predict
737O-linkedHMM predict
738Phosphothreonine(PKC)HMM predict
738O-linkedHMM predict
738O-linkedHMM predict
739O-linkedHMM predict
739O-linkedHMM predict
760Phosphoserine(IKK)HMM predict
762Phosphoserine(CK1)HMM predict
762Phosphoserine(CK2)HMM predict
762Phosphoserine(IKK)HMM predict
763O-linkedHMM predict
763Phosphoserine(CK1)HMM predict
765O-linkedHMM predict
767O-linkedHMM predict
768N-linkedHMM predict
794Phosphoserine(PKA)HMM predict
806MethylarginineHMM predict
808Phosphothreonine(PKA)HMM predict
835Phosphoserine(CK1)HMM predict
842Phosphoserine(IKK)HMM predict
843N-linkedHMM predict
845O-linkedHMM predict
847O-linkedHMM predict
869Phosphothreonine(PKC)HMM predict
882Phosphotyrosine(Syk)HMM predict
882Phosphotyrosine(INSR)HMM predict
882SulfotyrosineHMM predict
930Phosphoserine(IKK)HMM predict
930Phosphoserine(CK1)HMM predict
947Phosphoserine(PKG)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_032104
  • Location:chr1 200698493-200816902
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 200740964 200741938 974 0
CTCF CD4GSE12889 200699942 200700193 251 0
CTCF CD4GSE12889 200807544 200807892 348 0
CTCF CD4SISSRdata 200699942 200700193 251 0
CTCF CD4SISSRdata 200807544 200807892 348 0
CTCF JurkatGSE12889 200807509 200807800 291 0
CTCF G2GSE9613 200700015 200700296 281 0
CTCF G2GSE9613 200737054 200737510 456 0
CTCF G2GSE9613 200807522 200807857 335 0
ER MCF7GSE19013 200767739 200768437 698 0
Fos K562GSE19551 200719050 200719477 427 0
Fos K562GSE19551 200767824 200768309 485 0
Gata2 K562GSE18868 200789275 200789880 605 0
H3ac HepG2E 200707582 200707823 241 0
KLF4 hESGSE17917 200799478 200799875 397 0
Oct4 ESGSE20650 200803386 200803840 454 0
Oct4 hESGSE17917 200803307 200803804 497 0
Oct4 hESGSE21916 200803351 200803830 479 0
P300 T30-glioblastomaGSE21026 200740672 200741965 1293 0
RARA MCF7GSE15244 200724121 200724445 324 0
RARA MCF7GSE15244 200811820 200812902 1082 0
SRF HelaGSE8489 200740653 200742558 1905 0
TAF k562GSE8489 200707582 200707905 323 0
TFAP2C MCF7GSE21234 200792300 200792742 442 0
hScc1 BcellGSE12603 200700015 200700260 245 0
hScc1 BcellGSE12603 200736988 200737573 585 0
hScc1 BcellGSE12603 200807522 200807968 446 0
hScc1 CdLSGSE12603 200699822 200700760 938 0
hScc1 CdLSGSE12603 200736920 200737838 918 0
hScc1 CdLSGSE12603 200807522 200808174 652 0
p63 keratinocytesGSE17611 200779337 200779887 550 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
2168 mRNA PPP1R12B chr1 199049492 199289354 720 EST chr1 199172130 199172850 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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