AutismKB 2.0

Annotation Detail for NACA


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Basic Information Top
Gene Symbol:NACA ( MGC117224,NACA1 )
Gene Full Name: nascent polypeptide-associated complex alpha subunit
Band: 12q23-q24.1
Quick LinksEntrez ID:4666; OMIM: 601234; Uniprot ID:NACA_HUMAN; ENSEMBL ID: ENSG00000196531; HGNC ID: 7629
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
43Phosphoserine; by ILK1 (By similarity).
92Phosphothreonine.
108N6-acetyllysine.
142N6-acetyllysine.
159Phosphothreonine; by GSK3-beta (By
161Phosphothreonine.
166Phosphoserine.
186Phosphoserine.
191Phosphoserine.
Location(AA) Modifications Resource
43Phosphoserine (by ILK1) (By similarity).Swiss-Prot 53.0
43Phosphoserine (ILK)Phospho.ELM 6.0
159Phosphothreonine (by GSK3-beta) (Bysimilarity).Swiss-Prot 53.0
159Phosphothreonine (GSK-3beta)Phospho.ELM 6.0
161Phosphothreonine (By similarity).Swiss-Prot 53.0
166Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
12O-linkedHMM predict
25Phosphoserine(IKK)HMM predict
29Phosphoserine(CK2)HMM predict
31Phosphoserine(CK1)HMM predict
34Phosphoserine(CK1)HMM predict
70Phosphoserine(PKG)HMM predict
89Phosphothreonine(PKA)HMM predict
95Phosphothreonine(PKC)HMM predict
112Phosphotyrosine(Syk)HMM predict
114Phosphoserine(CDC2)HMM predict
132Phosphoserine(ATM)HMM predict
159Phosphothreonine(MAPK)HMM predict
166Phosphoserine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005594
  • Location:chr12 55392486-55405317
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 55405157 55405564 407 43
P300 T30-glioblastomaGSE21026 55404727 55406126 1399 109
PHF8 293TGSE20725 55404900 55405910 1010 88
Rb GrowingGSE19898 55405377 55405642 265 192
hScc1 CdLSGSE12603 55404978 55405676 698 10
p130 QuiescentGSE19898 55405534 55405839 305 369
p130 SenescentGSE19898 55404881 55406043 1162 145
p130 shRbQuiescentGSE19898 55404832 55406063 1231 130
p130 shRbSenescentGSE19898 55405202 55405553 351 60
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog hESGSE18292 55380982 55381143 161 11424
Oct4 hESGSE21916 55380853 55381262 409 11429
hScc1 G2GSE9613 55392319 55392522 203 66
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER Fulvestrant-MCF7GSE14664 55404866 55404954 88 0
ETS1 JurkatGSE17954 55404746 55405875 1129 0
FOXA1 DLD1GSE12801 55401985 55402429 444 0
FOXA1 MCF7GSE15244 55395922 55397192 1270 0
FOXA1 MCF7GSE15244 55400575 55401415 840 0
FOXA1 MCF7GSE15244 55404663 55405529 866 0
GATA3 MCF7GSE15244 55401484 55402094 610 0
H3K4me2 HCT116GSE10453 55403609 55404246 637 0
H3K4me3 colorectalcancer 55402880 55403099 219 0
H3K4me3 colorectalcancer 55403573 55405529 1956 0
H3ac HepG2E 55398901 55402429 3528 0
H3ac HepG2E 55402771 55403208 437 0
H3ac HepG2E 55403462 55405901 2439 0
RARA MCF7GSE15244 55401723 55402429 706 0
RARG MCF7GSE15244 55400499 55401278 779 0
RARG MCF7GSE15244 55403936 55405444 1508 0
TAF HelaGSE8489 55403798 55405879 2081 0
TAF k562GSE8489 55402771 55405879 3108 0
TFAP2C MCF7GSE21234 55401322 55401734 412 0
c MYCMCF7 55404711 55405603 892 0
hScc1 BcellGSE12603 55404860 55405564 704 0
p130 QuiescentGSE19898 55404943 55405495 552 0
p130 shRbSenescentGSE19898 55404941 55405117 176 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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