AutismKB 2.0

Annotation Detail for NEDD8


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Basic Information Top
Gene Symbol:NEDD8 ( FLJ43224,MGC104393,MGC125896,MGC125897,Nedd-8 )
Gene Full Name: neural precursor cell expressed, developmentally down-regulated 8
Band: 14q12
Quick LinksEntrez ID:4738; OMIM: 603171; Uniprot ID:NEDD8_HUMAN; ENSEMBL ID: ENSG00000129559; HGNC ID: 7732
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
48N6-acetyllysine.
Location(AA) Modifications Resource
76Glycyl lysine isopeptide (Gly-Lys)(interchain with K-? in acceptorproteins).Swiss-Prot 53.0
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006156
  • Location:chr14 23755911-23771411
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
RARG MCF7GSE15244 23755489 23756232 743 51
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 23771183 23771497 314 0
H3K4me3 colorectalcancer 23770463 23771224 761 0
Oct1 HelaGSE14283 23766837 23766903 66 0
RARG MCF7GSE15244 23770658 23771040 382 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018