Annotation Detail for NEK2
Basic Information Top
| Gene Symbol: | NEK2 ( HsPK21,NEK2A,NLK1 ) |
|---|---|
| Gene Full Name: | NIMA (never in mitosis gene a)-related kinase 2 |
| Band: | 1q32.3 |
| Quick Links | Entrez ID:4751; OMIM: 604043; Uniprot ID:NEK2_HUMAN; ENSEMBL ID: ENSG00000117650; HGNC ID: 7745 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 170 | Phosphothreonine; by autocatalysis | |
| 171 | Phosphoserine; by autocatalysis | |
| 175 | Phosphothreonine; by autocatalysis. | |
| 179 | Phosphothreonine; by autocatalysis. | |
| 184 | Phosphoserine. | |
| 241 | Phosphoserine; by autocatalysis. | |
| 296 | Phosphoserine. | |
| 299 | Phosphoserine. | |
| 300 | Phosphoserine. | |
| 356 | Phosphoserine. | |
| 387 | Phosphoserine. | |
| 390 | Phosphoserine. | |
| 397 | Phosphoserine. | |
| 402 | Phosphoserine. | |
| 428 | Phosphoserine. | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 175 | Phosphothreonine (by autocatalysis) (Bysimilarity). | Swiss-Prot 53.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 8 | Phosphotyrosine(Syk) | HMM predict |
| 41 | Phosphotyrosine(INSR) | HMM predict |
| 79 | N-linked | HMM predict |
| 83 | Phosphotyrosine(INSR) | HMM predict |
| 83 | Sulfotyrosine | HMM predict |
| 175 | O-linked | HMM predict |
| 175 | Phosphothreonine | HMM predict |
| 182 | Phosphotyrosine(SRC) | HMM predict |
| 182 | Phosphotyrosine(INSR) | HMM predict |
| 257 | Phosphotyrosine(INSR) | HMM predict |
| 296 | Phosphoserine(ATM) | HMM predict |
| 300 | Phosphoserine(IKK) | HMM predict |
| 300 | Phosphoserine(CDK) | HMM predict |
| 400 | Phosphoserine(CK1) | HMM predict |
| 402 | Phosphoserine(ATM) | HMM predict |
| 402 | Phosphoserine(CK1) | HMM predict |
| 402 | Phosphoserine(IKK) | HMM predict |
| 405 | Phosphothreonine(PKC) | HMM predict |
| 406 | Phosphoserine | HMM predict |
- RefSeq ID: NM_002497
- Location:chr1 209902744-209915589
- strand:-
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | CD4 | GSE12889 | 209920665 | 209921012 | 347 | 5249 |
| CTCF | CD4 | SISSRdata | 209920665 | 209921012 | 347 | 5249 |
| CTCF | G2 | GSE9613 | 209915240 | 209916012 | 772 | 37 |
| CTCF | G2 | GSE9613 | 209920563 | 209920906 | 343 | 5145 |
| CTCF | G2 | GSE9613 | 209934554 | 209935030 | 476 | 19203 |
| Fos | K562 | GSE19551 | 209915129 | 209916336 | 1207 | 143 |
| PHF8 | 293T | GSE20725 | 209915057 | 209916365 | 1308 | 122 |
| PHF8 | HeLa | GSE20725 | 209915096 | 209916112 | 1016 | 15 |
| RARG | MCF7 | GSE15244 | 209915481 | 209916012 | 531 | 157 |
| Rb | Senescent | GSE19898 | 209915457 | 209916045 | 588 | 162 |
| hScc1 | Bcell | GSE12603 | 209917724 | 209917936 | 212 | 2241 |
| hScc1 | Bcell | GSE12603 | 209920563 | 209921012 | 449 | 5198 |
| hScc1 | Bcell | GSE12603 | 209934591 | 209935601 | 1010 | 19507 |
| hScc1 | CdLS | GSE12603 | 209920563 | 209921040 | 477 | 5212 |
| hScc1 | G2 | GSE9613 | 209920563 | 209921040 | 477 | 5212 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | CD4 | GSE12889 | 209895230 | 209895480 | 250 | 7390 |
| CTCF | CD4 | SISSRdata | 209895230 | 209895480 | 250 | 7390 |
| CTCF | Jurkat | GSE12889 | 209895244 | 209895426 | 182 | 7410 |
| CTCF | G2 | GSE9613 | 209883319 | 209883537 | 218 | 19317 |
| CTCF | G2 | GSE9613 | 209894990 | 209895664 | 674 | 7418 |
| hScc1 | Bcell | GSE12603 | 209883355 | 209883752 | 397 | 19191 |
| hScc1 | Bcell | GSE12603 | 209894948 | 209895787 | 839 | 7377 |
| hScc1 | CdLS | GSE12603 | 209894623 | 209895823 | 1200 | 7522 |
| hScc1 | G2 | GSE9613 | 209894948 | 209895664 | 716 | 7439 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| E2F4 | G0 | GSE7516 | 209914847 | 209916012 | 1165 | 0 |
| E2F4 | S | GSE7516 | 209915022 | 209916012 | 990 | 0 |
| LIN54 | G0 | GSE7516 | 209915133 | 209916012 | 879 | 0 |
| LIN9 | G0 | GSE7516 | 209914095 | 209916012 | 1917 | 0 |
| LIN9 | S | GSE7516 | 209914604 | 209916012 | 1408 | 0 |
| p130 | Quiescent | GSE19898 | 209915113 | 209915882 | 769 | 0 |
| p130 | Senescent | GSE19898 | 209915025 | 209915951 | 926 | 0 |
| p130 | shRbQuiescent | GSE19898 | 209914956 | 209916142 | 1186 | 0 |
| p130 | shRbSenescent | GSE19898 | 209915019 | 209916065 | 1046 | 0 |
| p130 | G0 | GSE7516 | 209914405 | 209916012 | 1607 | 0 |
| p130 | S | GSE7516 | 209914640 | 209916012 | 1372 | 0 |
Validated miRNA targets