AutismKB 2.0

Annotation Detail for NEK3


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Basic Information Top
Gene Symbol:NEK3 ( HSPK36,MGC29949 )
Gene Full Name: NIMA (never in mitosis gene a)-related kinase 3
Band: 13q14.3
Quick LinksEntrez ID:4752; OMIM: 604044; Uniprot ID:NEK3_HUMAN; ENSEMBL ID: ENSG00000136098; HGNC ID: 7746
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
161Phosphothreonine; by autocatalysis (By
354Phosphoserine.
394Phosphoserine.
402Phosphothreonine.
479Phosphothreonine.
Location(AA) Modifications Resource
161Phosphothreonine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
479Phosphothreonine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
40Phosphoserine(IKK)HMM predict
76Phosphotyrosine(INSR)HMM predict
162Phosphotyrosine(Jak)HMM predict
181N-linkedHMM predict
220Phosphoserine(MAPK)HMM predict
220Phosphoserine(CDC2)HMM predict
241N-linkedHMM predict
249O-linkedHMM predict
288Phosphothreonine(MAPK)HMM predict
288PhosphothreonineHMM predict
288Phosphothreonine(CDC2)HMM predict
293Phosphothreonine(PKA)HMM predict
294N-linkedHMM predict
345N-linkedHMM predict
354Phosphoserine(PKG)HMM predict
401N-linkedHMM predict
447Phosphoserine(CK2)HMM predict
496MethyllysineHMM predict
498AlanineHMM predict
504CysteineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002498
  • Location:chr13 51604780-51631932
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 51638318 51638383 65 6418
Oct1 HelaGSE14283 51638416 51638443 27 6497
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 51631382 51631838 456 0
PHF8 HeLaGSE20725 51631266 51632009 743 0
hScc1 BcellGSE12603 51631382 51631693 311 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
7226 mRNA chr13 51601027 51604860 81 mRNA NEK3 chr13 51604779 51631933Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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