AutismKB 2.0

Annotation Detail for NFIB


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Basic Information Top
Gene Symbol:NFIB ( HMGIC/NFIB,NFI-RED,NFIB2,NFIB3 )
Gene Full Name: nuclear factor I/B
Band: 9p23-p22.3
Quick LinksEntrez ID:4781; OMIM: 600728; Uniprot ID:NFIB_HUMAN; ENSEMBL ID: ENSG00000147862; HGNC ID: 7785
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
63Phosphoserine (By similarity).
264Phosphoserine.
265Phosphoserine.
292Phosphoserine (By similarity).
295Phosphoserine (By similarity).
328Phosphoserine.
332Phosphoserine.
Location(AA) Modifications Resource
264Phosphoserine (By similarity).Swiss-Prot 53.0
292Phosphoserine (By similarity).Swiss-Prot 53.0
295Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
41Phosphotyrosine(Jak)HMM predict
50Phosphoserine(CK2)HMM predict
50Phosphoserine(CK1)HMM predict
183SulfotyrosineHMM predict
194Phosphoserine(CDC2)HMM predict
194Phosphoserine(IKK)HMM predict
194Phosphoserine(ATM)HMM predict
246Phosphoserine(ATM)HMM predict
249Phosphotyrosine(Syk)HMM predict
264PhosphoserineHMM predict
265Phosphoserine(IKK)HMM predict
265Phosphoserine(MAPK)HMM predict
265Phosphoserine(CDC2)HMM predict
265Phosphoserine(ATM)HMM predict
269O-linkedHMM predict
286Phosphothreonine(PKC)HMM predict
292O-linkedHMM predict
292Phosphoserine(CDC2)HMM predict
292Phosphoserine(CDK)HMM predict
295Phosphoserine(MAPK)HMM predict
295Phosphoserine(IKK)HMM predict
295Phosphoserine(CDC2)HMM predict
312Phosphoserine(ATM)HMM predict
315Phosphothreonine(PKC)HMM predict
328Phosphoserine(CDC2)HMM predict
333Phosphoserine(IKK)HMM predict
356O-linkedHMM predict
356O-linkedHMM predict
357O-linkedHMM predict
359Phosphothreonine(CDK)HMM predict
359Phosphothreonine(CDC2)HMM predict
364O-linkedHMM predict
364Phosphoserine(MAPK)HMM predict
379O-linkedHMM predict
402Phosphotyrosine(INSR)HMM predict
410O-linkedHMM predict
410Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005596
  • Location:chr9 14071847-14303944
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FoxA1 MCF7MACSdata 14310605 14310843 238 6780
P300 T30-glioblastomaGSE21026 14309979 14311132 1153 6611
PolII HeLaGSE12783 14311482 14313973 2491 8783
Rb QuiescentGSE19898 14312789 14313009 220 8955
Rb SenescentGSE19898 14312524 14312764 240 8700
Rb shRbQuiescentGSE19898 14310744 14310963 219 6909
Rb shRbSenescenceGSE19898 14310585 14310924 339 6810
TAF k562GSE8489 14309835 14310650 815 6298
TAF k562GSE8489 14311666 14312242 576 8010
TAF k562GSE8489 14313016 14313623 607 9375
TFAP2C MCF7GSE21234 14321078 14321873 795 17531
hScc1 BcellGSE12603 14312206 14312888 682 8603
p130 QuiescentGSE19898 14310625 14310953 328 6845
p130 QuiescentGSE19898 14312874 14313156 282 9071
p130 shRbQuiescentGSE19898 14310518 14310977 459 6803
p130 shRbSenescentGSE19898 14310645 14310997 352 6877
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 14070284 14070493 209 1459
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
AR prostate-cancerGSE14092 14096566 14097240 674 0
ER E2-MCF7GSE14664 14158087 14158131 44 0
ER E2-MCF7GSE14664 14266937 14266972 35 0
ER E2-MCF7GSE14664 14299057 14299089 32 0
ER Fulvestrant-MCF7GSE14664 14244372 14244405 33 0
ER MCF7GSE19013 14169386 14169913 527 0
ER MCF7GSE19013 14241052 14241895 843 0
ER MCF7GSE19013 14251939 14252419 480 0
FOXA1 MCF7GSE15244 14087823 14088771 948 0
FOXA1 MCF7GSE15244 14169409 14169899 490 0
FOXA1 MCF7GSE15244 14228444 14228839 395 0
FOXA1 MCF7GSE15244 14241137 14241788 651 0
FoxA1 MCF7MACSdata 14088135 14088348 213 0
FoxA1 MCF7MACSdata 14241416 14241579 163 0
H3K4me3 colorectalcancer 14302098 14302953 855 0
H3K4me3 colorectalcancer 14303309 14303677 368 0
Oct1 HelaGSE14283 14230430 14230462 32 0
Oct1 HelaGSE14283 14232742 14232770 28 0
Oct1 HelaGSE14283 14244586 14244634 48 0
P300 T30-glioblastomaGSE21026 14086146 14087013 867 0
P300 T30-glioblastomaGSE21026 14211305 14212344 1039 0
PAX3-FKHR Rh4GSE19063 14078514 14080715 2201 0
RARA MCF7GSE15244 14211626 14212494 868 0
RARA MCF7GSE15244 14227722 14228976 1254 0
RARA MCF7GSE15244 14241036 14242011 975 0
RNAII Tamoxifen-MCF7GSE14664 14244569 14244632 63 0
TAF k562GSE8489 14264614 14264968 354 0
TFAP2C MCF7GSE21234 14201467 14201796 329 0
TFAP2C MCF7GSE21234 14228039 14228515 476 0
TFAP2C MCF7GSE21234 14241085 14241800 715 0
TFAP2C MCF7GSE21234 14251937 14252452 515 0
p63 keratinocytesGSE17611 14126777 14127638 861 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-125b hsa-mir-125b-1 11 21375733
hsa-miR-125b hsa-mir-125b-2 21 21375733
hsa-miR-182 hsa-mir-182 7 21375733
hsa-miR-182* hsa-mir-182 7 21375733
hsa-miR-183 hsa-mir-183 7 21375733
hsa-miR-183* hsa-mir-183 7 21375733
hsa-miR-195 hsa-mir-195 17 21375733
hsa-miR-195* hsa-mir-195 17 21375733
hsa-miR-21 hsa-mir-21 17 21375733
hsa-miR-21 hsa-mir-21 17 20417062
hsa-miR-21 hsa-mir-21 17 18384814
hsa-miR-21* hsa-mir-21 17 21375733
hsa-miR-21* hsa-mir-21 17 20417062
hsa-miR-21* hsa-mir-21 17 18384814
hsa-miR-221 hsa-mir-221 X 20417062
hsa-miR-221* hsa-mir-221 X 20417062
hsa-miR-222 hsa-mir-222 X 20417062
hsa-miR-222* hsa-mir-222 X 20417062
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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