AutismKB 2.0

Annotation Detail for NKX3-1


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Basic Information Top
Gene Symbol:NKX3-1 ( BAPX2,NKX3,NKX3.1,NKX3A )
Gene Full Name: NK3 homeobox 1
Band: 8p21.2
Quick LinksEntrez ID:4824; OMIM: 602041; Uniprot ID:NKX31_HUMAN; ENSEMBL ID: ENSG00000167034; HGNC ID: 7838
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
21Phosphothreonine(CDC2)HMM predict
21Phosphothreonine(MAPK)HMM predict
21Phosphothreonine(CDK)HMM predict
21PhosphothreonineHMM predict
23O-linkedHMM predict
48Phosphoserine(CAMK2)HMM predict
48Phosphoserine(ATM)HMM predict
68MethylarginineHMM predict
108N-linkedHMM predict
119Phosphothreonine(CDC2)HMM predict
144Phosphoserine(PKG)HMM predict
148Phosphotyrosine(Syk)HMM predict
179Phosphothreonine(PKC)HMM predict
196Phosphoserine(PKA)HMM predict
231ProlineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006167
  • Location:chr8 23592172-23596394
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 23606142 23606385 243 9869
CTCF CD4SISSRdata 23606142 23606385 243 9869
CTCF HelaGSE12889 23606173 23606355 182 9870
CTCF JurkatGSE12889 23606188 23606550 362 9975
CTCF G2GSE9613 23605754 23606891 1137 9928
CTCF G2GSE9613 23616030 23616586 556 19914
H3K4me3 colorectalcancer 23596397 23597143 746 376
Oct1 HelaGSE14283 23600473 23600534 61 4109
USF1 HepG2E 23596718 23597273 555 601
hScc1 BcellGSE12603 23605754 23606618 864 9792
hScc1 BcellGSE12603 23616175 23616586 411 19986
hScc1 CdLSGSE12603 23605534 23606618 1084 9682
hScc1 G2GSE9613 23605754 23606544 790 9755
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 23581706 23583071 1365 9784
CTCF G2GSE9613 23577352 23577722 370 14636
ER E2-MCF7GSE14664 23590064 23590099 35 2091
Myc K562GSE19551 23582099 23582470 371 9888
Oct1 H2O2-HelaGSE14283 23590064 23590096 32 2093
Oct1 HelaGSE14283 23590064 23590098 34 2092
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 23595949 23596679 730 0
H3K4me3 colorectalcancer 23595118 23595885 767 0
H3ac HepG2E 23595118 23595528 410 0
NRSF pAbJurkat 23596069 23596644 575 0
hScc1 CdLSGSE12603 23595949 23596535 586 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018