AutismKB 2.0

Annotation Detail for NOS1


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Basic Information Top
Gene Symbol:NOS1 ( IHPS1,N-NOS,NC-NOS,NOS,bNOS,nNOS )
Gene Full Name: nitric oxide synthase 1 (neuronal)
Band: 12q24.22
Quick LinksEntrez ID:4842; OMIM: 163731; Uniprot ID:NOS1_HUMAN; ENSEMBL ID: ENSG00000089250; HGNC ID: 7872
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
37Phosphoserine(PKG)HMM predict
110O-linkedHMM predict
163Phosphotyrosine(Syk)HMM predict
163SulfotyrosineHMM predict
171Phosphoserine(CK1)HMM predict
192Phosphothreonine(PKC)HMM predict
192Phosphothreonine(PKA)HMM predict
214Phosphoserine(CK1)HMM predict
224O-linkedHMM predict
288Phosphoserine(CDK)HMM predict
288O-linkedHMM predict
292Phosphoserine(CDC2)HMM predict
296N-linkedHMM predict
298Phosphoserine(CDC2)HMM predict
334Phosphotyrosine(Jak)HMM predict
334Phosphotyrosine(INSR)HMM predict
344Phosphoserine(ATM)HMM predict
379Phosphoserine(PKA)HMM predict
416N-linkedHMM predict
671Phosphotyrosine(Jak)HMM predict
689O-linkedHMM predict
718Phosphothreonine(PKC)HMM predict
725N-linkedHMM predict
727Phosphothreonine(CDK)HMM predict
727Phosphothreonine(MAPK)HMM predict
727Phosphothreonine(CDC2)HMM predict
729Phosphothreonine(PKC)HMM predict
846Phosphotyrosine(Jak)HMM predict
852Phosphoserine(PKA)HMM predict
854Phosphoserine(CK2)HMM predict
857Phosphoserine(CK1)HMM predict
859Phosphoserine(ATM)HMM predict
863Phosphoserine(IKK)HMM predict
959N-linkedHMM predict
960N-linkedHMM predict
965N-linkedHMM predict
1025N-linkedHMM predict
1083N-linkedHMM predict
1102Phosphotyrosine(Syk)HMM predict
1110Phosphothreonine(MAPK)HMM predict
1110Phosphothreonine(CDK)HMM predict
1148N-linkedHMM predict
1181Phosphoserine(IKK)HMM predict
1352Phosphotyrosine(INSR)HMM predict
1378Phosphoserine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000620
  • Location:chr12 116135361-116283964
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 116289281 116289464 183 5408
CTCF CD4SISSRdata 116289281 116289464 183 5408
CTCF HelaGSE12889 116289296 116289471 175 5419
CTCF JurkatGSE12889 116289144 116289577 433 5396
CTCF G2GSE9613 116284087 116284423 336 291
CTCF G2GSE9613 116287099 116287512 413 3341
CTCF G2GSE9613 116288477 116288621 144 4585
CTCF G2GSE9613 116289010 116290440 1430 5761
Fos K562GSE19551 116299969 116300299 330 16170
H3K27me3 colorectalcancer 116283877 116285866 1989 907
H3K27me3 colorectalcancer 116288263 116289010 747 4672
NRSF pAbJurkat 116284204 116285342 1138 809
STAT1 IFNSISSRdata 116289046 116289645 599 5381
hScc1 BcellGSE12603 116288980 116289722 742 5387
hScc1 CdLSGSE12603 116288980 116289948 968 5500
hScc1 G2GSE9613 116288980 116290359 1379 5705
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 116134797 116135061 264 433
CTCF CD4SISSRdata 116134797 116135061 264 433
CTCF JurkatGSE12889 116134751 116135017 266 478
CTCF G2GSE9613 116134303 116135234 931 593
hScc1 BcellGSE12603 116134674 116135163 489 443
hScc1 CdLSGSE12603 116134674 116135234 560 408
hScc1 G2GSE9613 116134674 116135269 595 390
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 116158677 116158945 268 0
CTCF CD4SISSRdata 116158677 116158945 268 0
CTCF G2GSE9613 116136955 116137218 263 0
CTCF G2GSE9613 116142174 116142490 316 0
CTCF G2GSE9613 116148758 116148944 186 0
CTCF G2GSE9613 116153806 116154419 613 0
CTCF G2GSE9613 116156679 116157058 379 0
CTCF G2GSE9613 116158380 116159311 931 0
CTCF G2GSE9613 116160187 116160396 209 0
CTCF G2GSE9613 116187589 116187763 174 0
CTCF G2GSE9613 116194652 116195099 447 0
CTCF G2GSE9613 116202842 116203091 249 0
CTCF G2GSE9613 116216206 116216438 232 0
CTCF G2GSE9613 116219883 116220108 225 0
CTCF G2GSE9613 116247059 116247534 475 0
CTCF G2GSE9613 116248827 116248960 133 0
CTCF G2GSE9613 116252976 116253998 1022 0
CTCF G2GSE9613 116282585 116283690 1105 0
FOXA1 DLD1GSE12801 116264828 116265201 373 0
FOXA1 MCF7GSE15244 116231570 116231882 312 0
H3ac HepG2E 116141811 116142073 262 0
IGF1R DFBGSE23792 116157996 116158382 386 0
NFkBII GM12878GSE19485 116136506 116137579 1073 0
NFkBII GM12892GSE19485 116136593 116137754 1161 0
NRSF pAbJurkat 116226382 116226569 187 0
NRSF pAbJurkat 116246928 116247534 606 0
RARA MCF7GSE15244 116182352 116182565 213 0
RARG MCF7GSE15244 116182352 116182565 213 0
RARG MCF7GSE15244 116269758 116270440 682 0
TAF HelaGSE8489 116275699 116275983 284 0
hScc1 BcellGSE12603 116158559 116159173 614 0
hScc1 CdLSGSE12603 116158596 116159140 544 0
hScc1 G2GSE9613 116158634 116159311 677 0
hScc1 G2GSE9613 116219883 116220108 225 0
p63 keratinocytesGSE17611 116250498 116251343 845 0
p63 keratinocytesGSE17611 116266651 116267598 947 0
p63 keratinocytesGSE17611 116272095 116272971 876 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1 hsa-mir-1-2 18 20727829
hsa-miR-1 hsa-mir-1-1 20 20727829
hsa-miR-206 hsa-mir-206 6 20727829
hsa-miR-29a hsa-mir-29a 7 20727829
hsa-miR-29a* hsa-mir-29a 7 20727829
hsa-miR-29b hsa-mir-29b-1 7 20727829
hsa-miR-29b hsa-mir-29b-2 1 20727829
hsa-miR-29b-1* hsa-mir-29b-1 7 20727829
hsa-miR-29b-2* hsa-mir-29b-2 1 20727829
hsa-miR-29c hsa-mir-29c 1 20727829
hsa-miR-29c* hsa-mir-29c 1 20727829
hsa-miR-30a hsa-mir-30a 6 21134262
hsa-miR-30a* hsa-mir-30a 6 21134262
hsa-miR-30b hsa-mir-30b 8 21134262
hsa-miR-30b* hsa-mir-30b 8 21134262
hsa-miR-30c hsa-mir-30c-2 6 21134262
hsa-miR-30c hsa-mir-30c-1 1 21134262
hsa-miR-30c-1* hsa-mir-30c-1 1 21134262
hsa-miR-30c-2* hsa-mir-30c-2 6 21134262
hsa-miR-30d hsa-mir-30d 8 21134262
hsa-miR-30d* hsa-mir-30d 8 21134262
hsa-miR-30e hsa-mir-30e 1 21134262
hsa-miR-30e* hsa-mir-30e 1 21134262
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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