AutismKB 2.0

Annotation Detail for CNOT3


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Basic Information Top
Gene Symbol:CNOT3 ( KIAA0691,LENG2,NOT3,NOT3H )
Gene Full Name: CCR4-NOT transcription complex, subunit 3
Band: 19q13.42
Quick LinksEntrez ID:4849; OMIM: 604910; Uniprot ID:CNOT3_HUMAN; ENSEMBL ID: ENSG00000088038; HGNC ID: 7879
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
292Phosphothreonine.
299Phosphoserine.
Location(AA) Modifications Resource
299Phosphoserine.Swiss-Prot 53.0
299PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
144Phosphoserine(CK2)HMM predict
148Phosphoserine(CK1)HMM predict
153Phosphothreonine(PKC)HMM predict
209Phosphotyrosine(Syk)HMM predict
214Phosphoserine(ATM)HMM predict
226SulfotyrosineHMM predict
242O-linkedHMM predict
255N-linkedHMM predict
258O-linkedHMM predict
259O-linkedHMM predict
260O-linkedHMM predict
260Phosphothreonine(MAPK)HMM predict
260Phosphothreonine(CDK)HMM predict
262O-linkedHMM predict
263Phosphoserine(IKK)HMM predict
263O-linkedHMM predict
264O-linkedHMM predict
265O-linkedHMM predict
266O-linkedHMM predict
267O-linkedHMM predict
268O-linkedHMM predict
268Phosphoserine(CDK)HMM predict
268Phosphoserine(CDC2)HMM predict
273Phosphoserine(CDC2)HMM predict
276N-linkedHMM predict
281N-linkedHMM predict
291Phosphoserine(PKB)HMM predict
294Phosphoserine(IKK)HMM predict
297Phosphoserine(ATM)HMM predict
299Phosphoserine(CDC2)HMM predict
299Phosphoserine(IKK)HMM predict
303N-linkedHMM predict
316Phosphoserine(MAPK)HMM predict
316Phosphoserine(CDC2)HMM predict
322O-linkedHMM predict
322O-linkedHMM predict
325O-linkedHMM predict
332O-linkedHMM predict
332O-linkedHMM predict
336O-linkedHMM predict
337O-linkedHMM predict
351O-linkedHMM predict
358Phosphoserine(CDC2)HMM predict
358PhosphoserineHMM predict
365O-linkedHMM predict
371Phosphotyrosine(Abl)HMM predict
381O-linkedHMM predict
384O-linkedHMM predict
385O-linkedHMM predict
386Phosphothreonine(PKC)HMM predict
392Phosphoserine(IKK)HMM predict
392O-linkedHMM predict
396O-linkedHMM predict
414Phosphoserine(CK1)HMM predict
436Phosphoserine(CDC2)HMM predict
443Phosphoserine(CK1)HMM predict
449N-linkedHMM predict
459O-linkedHMM predict
468Phosphothreonine(PKC)HMM predict
469O-linkedHMM predict
489N-linkedHMM predict
490N-linkedHMM predict
506O-linkedHMM predict
507Phosphoserine(MAPK)HMM predict
507Phosphoserine(CDC2)HMM predict
509O-linkedHMM predict
509Phosphothreonine(CDK)HMM predict
541Phosphoserine(CDC2)HMM predict
554Phosphoserine(CK2)HMM predict
575O-linkedHMM predict
576O-linkedHMM predict
576O-linkedHMM predict
581O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014516
  • Location:chr19 59333260-59351238
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me2 HCT116GSE10453 59331692 59332557 865 1136
H3ac HepG2E 59331654 59332458 804 1205
LIN9 G0GSE7516 59332525 59333416 891 290
P300 T0-glioblastomaGSE21026 59332160 59333500 1340 431
P300 T30-glioblastomaGSE21026 59332022 59333588 1566 456
PHF8 293TGSE20725 59331962 59333044 1082 758
Rb GrowingGSE19898 59332771 59333165 394 293
Rb QuiescentGSE19898 59332584 59333104 520 417
Rb SenescentGSE19898 59332695 59333552 857 137
Rb shRbQuiescentGSE19898 59332127 59332302 175 1046
Rb shRbSenescenceGSE19898 59332814 59333118 304 295
TFAP2C MCF7GSE21234 59332338 59333380 1042 402
p130 QuiescentGSE19898 59332776 59333387 611 179
p130 SenescentGSE19898 59332217 59333429 1212 438
p130 shRbQuiescentGSE19898 59332464 59333439 975 309
p130 shRbSenescentGSE19898 59332025 59332415 390 1041
p130 shRbSenescentGSE19898 59332501 59333379 878 321
p130 G0GSE7516 59332525 59333393 868 302
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 59333279 59333728 449 0
PHF8 HeLaGSE20725 59332870 59334013 1143 0
hScc1 BcellGSE12603 59333243 59334115 872 0
hScc1 BcellGSE12603 59343645 59344110 465 0
hScc1 BcellGSE12603 59348513 59348834 321 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
13613 mRNA CNOT3 chr19 59333260 59351239 47 mRNA LENG1 chr19 59351192 59355258Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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