AutismKB 2.0

Annotation Detail for NPAS2


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Basic Information Top
Gene Symbol:NPAS2 ( FLJ23138,MGC71151,MOP4,PASD4,bHLHe9 )
Gene Full Name: neuronal PAS domain protein 2
Band: 2q11.2
Quick LinksEntrez ID:4862; OMIM: 603347; Uniprot ID:NPAS2_HUMAN; ENSEMBL ID: ENSG00000170485; HGNC ID: 7895
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
13PhosphoserineHMM predict
105Phosphoserine(PKA)HMM predict
154Phosphoserine(CDK)HMM predict
154Phosphoserine(CDC2)HMM predict
185Phosphotyrosine(SRC)HMM predict
187Phosphotyrosine(Jak)HMM predict
202Phosphoserine(CDC2)HMM predict
256Phosphoserine(CK1)HMM predict
287SulfotyrosineHMM predict
403N-linkedHMM predict
407Phosphoserine(MAPK)HMM predict
407Phosphoserine(IKK)HMM predict
407Phosphoserine(CDC2)HMM predict
412Phosphoserine(CK1)HMM predict
414Phosphoserine(CK1)HMM predict
421O-linkedHMM predict
424O-linkedHMM predict
427O-linkedHMM predict
429Phosphothreonine(MAPK)HMM predict
469Phosphoserine(CDK)HMM predict
471O-linkedHMM predict
472Phosphoserine(IKK)HMM predict
540Phosphoserine(IKK)HMM predict
554Phosphoserine(IKK)HMM predict
556Phosphoserine(CK1)HMM predict
590O-linkedHMM predict
595Phosphothreonine(PKC)HMM predict
629Phosphoserine(IKK)HMM predict
632Phosphoserine(CDC2)HMM predict
638O-linkedHMM predict
644O-linkedHMM predict
646N-linkedHMM predict
648O-linkedHMM predict
649O-linkedHMM predict
654Phosphoserine(ATM)HMM predict
654Phosphoserine(IKK)HMM predict
658Phosphoserine(IKK)HMM predict
663Phosphoserine(CDC2)HMM predict
677Phosphoserine(ATM)HMM predict
708Phosphoserine(ATM)HMM predict
721N-linkedHMM predict
723O-linkedHMM predict
724O-linkedHMM predict
744Phosphoserine(ATM)HMM predict
744Phosphoserine(IKK)HMM predict
747O-linkedHMM predict
747Phosphoserine(IKK)HMM predict
770Phosphoserine(MAPK)HMM predict
778Phosphoserine(IKK)HMM predict
785Phosphoserine(ATM)HMM predict
811Phosphoserine(CK2)HMM predict
811Phosphoserine(PKA)HMM predict
811Phosphoserine(PKG)HMM predict
812Phosphoserine(PKB)HMM predict
812Phosphoserine(CK1)HMM predict
812Phosphoserine(PKG)HMM predict
814Phosphoserine(CK2)HMM predict
814Phosphoserine(CK1)HMM predict
817Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002518
  • Location:chr2 100803044-100979718
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF HelaGSE12889 100801559 100801743 184 1394
CTCF G2GSE9613 100783560 100783892 332 19319
CTCF G2GSE9613 100785166 100785316 150 17804
CTCF G2GSE9613 100801276 100801960 684 1427
SRF HelaGSE8489 100799089 100801507 2418 2747
hScc1 BcellGSE12603 100801596 100801909 313 1292
hScc1 BcellGSE12603 100802156 100802396 240 769
hScc1 G2GSE9613 100801276 100804745 3469 34
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 100885430 100886330 900 0
CTCF CD4GSE12889 100967844 100968043 199 0
CTCF CD4SISSRdata 100967844 100968043 199 0
CTCF G2GSE9613 100802257 100804010 1753 0
CTCF G2GSE9613 100804325 100804580 255 0
CTCF G2GSE9613 100853810 100854180 370 0
CTCF G2GSE9613 100861009 100861239 230 0
CTCF G2GSE9613 100862595 100862845 250 0
CTCF G2GSE9613 100870122 100870348 226 0
CTCF G2GSE9613 100888577 100888950 373 0
CTCF G2GSE9613 100923684 100923869 185 0
CTCF G2GSE9613 100943421 100943713 292 0
CTCF G2GSE9613 100952830 100953180 350 0
CTCF G2GSE9613 100959466 100959689 223 0
CTCF G2GSE9613 100963681 100964308 627 0
CTCF G2GSE9613 100964798 100965535 737 0
CTCF G2GSE9613 100967606 100968250 644 0
CTCF G2GSE9613 100971165 100971889 724 0
CTCF G2GSE9613 100973700 100974265 565 0
ER Fulvestrant-MCF7GSE14664 100956403 100956440 37 0
ER MCF7GSE19013 100870572 100871287 715 0
FOXA1 MCF7GSE15244 100885641 100887182 1541 0
Fos K562GSE19551 100885696 100886217 521 0
H3ac HepG2E 100858589 100860000 1411 0
Myc K562GSE19551 100967815 100968070 255 0
Nanog hESGSE18292 100853713 100853915 202 0
Oct1 H2O2-HelaGSE14283 100814253 100814288 35 0
Oct1 H2O2-HelaGSE14283 100900486 100900523 37 0
Oct1 H2O2-HelaGSE14283 100910079 100910106 27 0
Oct1 H2O2-HelaGSE14283 100927771 100927808 37 0
Oct1 HelaGSE14283 100900486 100900523 37 0
Oct1 HelaGSE14283 100927771 100927806 35 0
P300 T0-glioblastomaGSE21026 100885680 100886371 691 0
P300 T30-glioblastomaGSE21026 100885327 100887090 1763 0
RARA MCF7GSE15244 100837086 100837652 566 0
RARA MCF7GSE15244 100865577 100867437 1860 0
RARA MCF7GSE15244 100885641 100887182 1541 0
Sox2 hESGSE18292 100853730 100853918 188 0
TFAP2C MCF7GSE21234 100885638 100886288 650 0
TFAP2C MCF7GSE21234 100886591 100887323 732 0
USF1 HepG2E 100858411 100860038 1627 0
USF2 HepG2E 100858589 100859464 875 0
hScc1 BcellGSE12603 100888614 100888830 216 0
hScc1 BcellGSE12603 100943349 100943568 219 0
hScc1 BcellGSE12603 100967533 100968250 717 0
hScc1 CdLSGSE12603 100967419 100968250 831 0
hScc1 G2GSE9613 100923684 100923831 147 0
hScc1 G2GSE9613 100967451 100968250 799 0
p130 SenescentGSE19898 100904986 100905134 148 0
p130 SenescentGSE19898 100926421 100926630 209 0
p130 shRbQuiescentGSE19898 100840560 100841251 691 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-519e hsa-mir-519e 19 21140207
hsa-miR-519e* hsa-mir-519e 19 21140207
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
14725 mRNA NPAS2 chr2 100895130 101071805 610 mRNA NPAS2 chr2 101068655 101077224Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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